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73 Cards in this Set

  • Front
  • Back
the time is approximately day 18. ____ and ____formation are now complete. The next stage is formation of the ______.
gastrulation and notochord formation

next stage is formation of nervous system
Neurulation
process of neural tube formation, which differentiates out fo the ectoderm overlying the notochord

the receptive area is an oval patch stretching from oral palte to primitive node, this area thickens into a neural plate
neurula
receptive area.
ectoderm migrates into area above the notochord as it grow from the primitive pit
the neural plate has a layer of what at the cell's apical surface?
actin filaments...these start to contract to initiate neural folding
What activates the folding cycle?
SHH expressed by notochord..
later, the basal neural tube will also express SHH
Neural fold
edges of peural plate that fold over to create a groove
neural groove
groove created by folding of edges of neural plate
neural crest cells
cells that migrate as mesenchyme from the neural fold
simultaneously with neural tube formation is the early ___
somites
neural tube
neural folds come together to fuse....now the neural groove becomes neural tube
neural canal
space inside the neural tube
some neural crest aggregate ____, but many of the cells migrate through the body
posteriorly
day 20, the folds begin to form at the center of the embry. the anterior and posterior prarts still have_____
neural plate
day 22, the center folds have already fused and the fusion of the_____ continue ___and____
neural folds continue anteriorly and posteriorly
day 23, only __-small connections between amnion and neural tube
2
rostral neuropore and caudal neuropore

btw. proximal part of the neural tube starts to differentiate into the brain and brainstem
secondary neurulation:
beyond the caudal neuropore, the neural tube (lower sacral)forms by development of medullary core, which secondarily cannulates and joins up with the rest of the neural tube
What is the mechanism of the delay of neural tube closure
the tube eventually closes, but the delay causes a failure of the overlying mesoderm to form bone, except in rare instances
rostral neuropore
normally closes day 25
dealy in what results in exencephaly
rostal neuropore closure
caudal neuropore
normally closes day 27.

delay results in spina bifida
In body folding, the region of brain grows disproportionately ___, grwoing up and into ____.
fast
amniotic cavity
In body folding, the heart and spetumtransversum grow which way?
underneath
How is the umbilicus produced?
restriction around the umbilical vesicle and connecting stalk
body folding results in what folds?
head fold
tail fold
lateral body folds
when does the umbilical vesicle detach?
6 wks
what are three parts of the brain and brainstem?
prosencephalon
mesencephalon
rhombencephalon
germinal layers will dominate the next few cards
have fun
skin
ectoderm
epidermal glands
ectoderm
hair, nails
ectoderm
eye: lens, corneal epithelium
ectoderm
inner ear labyrinth
ectoderm
anterior pituitary
ectoderm
tooth enamel
ectoderm
neural tissue
=neuroectoderm is a large, specialized derivative of ectoderm
brain, brainstem and spinal cord
neuroectoderm
eye: retina, pigment epithelium, potic nerve part of iris
neuroectoderm
pas nervosa of pituitary gland
neuroectoderm
epithelium of alimentary canal
endoderm
parenchyma of pancreas and liver
endoderm
thyroid, parathyroid
endoderm
thymus
endoderm
lung and trachea
endoderm
middle ear epithelium
endoderm
urinary bladder and urethral epithelia
endoderm
vaginal epithelium
endoderm
endoderm forms epithelial surfaces, but the supporting elements of any given organ are derived from its ____
mesoderm
what are the regions of the mesoderm(6)?
somite
intermediate mesoderm
lateral plate mesoderm
intraembryonic celom
notochord
septum transversum
somite differentiation begins from ____
undifferentiated mesoderm
early somite contains a _____
somatocoele
somite differentiation results in 2 layers, which are?
dermomyotome
sclerotome
dermomyotome differentiates into what?
dermatome and myotome
vertebral bones and intervertebral disks from
sclerotome
dermis of skin, ventral skeletal muscle, doral skeletal muscle
dermomyotome
kidney, ureter and ductus deferens, gonads come from:
intermediate mesoderm
lateral plate mesoderm consists of what three mesoderms?
somatic mesoderm (somatopleure)
intraembryonic celom
splanchnic mesoderm (splanchonopleure)
bones, cartilage, fascia and other CT around periphery of body
somatic mesoderm
visceral smooth muscle, fascia and CT of viscera, associated vasculature
splanchnic mesoderm
what migrates with heart during embryo folding?
septum transversum
what separates thorax from abdomen early in development?
septum transversum
septum transversum participates in what developmen?
venous cardiac
the final derivative of the septum transversum is a part of what?
central tendon of diaphragm
neural crest
arises from neural folds
melanocytes of skin
from neural crest
all parts of peripherial nervous system, including ganglion cells, support cells, etc
from neural crest
in and near head can form bone, cartilage, and other CT of the pharyngeal arches
from neural crest
adrenal medulla
from neural crest (NOT adrenal cortex)
bulbar ridges (spiral spetum) of the heart
from neural crest
meninges
from neural crest
somitomeres
like somites but without sclerotome
bone and cartilage of head
neural crest mesoderm
connective tissues of branchial arches
neural crest
head muscles
somitomeres