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73 Cards in this Set
- Front
- Back
the time is approximately day 18. ____ and ____formation are now complete. The next stage is formation of the ______.
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gastrulation and notochord formation
next stage is formation of nervous system |
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Neurulation
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process of neural tube formation, which differentiates out fo the ectoderm overlying the notochord
the receptive area is an oval patch stretching from oral palte to primitive node, this area thickens into a neural plate |
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neurula
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receptive area.
ectoderm migrates into area above the notochord as it grow from the primitive pit |
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the neural plate has a layer of what at the cell's apical surface?
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actin filaments...these start to contract to initiate neural folding
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What activates the folding cycle?
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SHH expressed by notochord..
later, the basal neural tube will also express SHH |
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Neural fold
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edges of peural plate that fold over to create a groove
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neural groove
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groove created by folding of edges of neural plate
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neural crest cells
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cells that migrate as mesenchyme from the neural fold
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simultaneously with neural tube formation is the early ___
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somites
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neural tube
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neural folds come together to fuse....now the neural groove becomes neural tube
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neural canal
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space inside the neural tube
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some neural crest aggregate ____, but many of the cells migrate through the body
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posteriorly
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day 20, the folds begin to form at the center of the embry. the anterior and posterior prarts still have_____
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neural plate
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day 22, the center folds have already fused and the fusion of the_____ continue ___and____
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neural folds continue anteriorly and posteriorly
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day 23, only __-small connections between amnion and neural tube
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2
rostral neuropore and caudal neuropore btw. proximal part of the neural tube starts to differentiate into the brain and brainstem |
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secondary neurulation:
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beyond the caudal neuropore, the neural tube (lower sacral)forms by development of medullary core, which secondarily cannulates and joins up with the rest of the neural tube
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What is the mechanism of the delay of neural tube closure
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the tube eventually closes, but the delay causes a failure of the overlying mesoderm to form bone, except in rare instances
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rostral neuropore
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normally closes day 25
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dealy in what results in exencephaly
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rostal neuropore closure
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caudal neuropore
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normally closes day 27.
delay results in spina bifida |
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In body folding, the region of brain grows disproportionately ___, grwoing up and into ____.
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fast
amniotic cavity |
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In body folding, the heart and spetumtransversum grow which way?
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underneath
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How is the umbilicus produced?
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restriction around the umbilical vesicle and connecting stalk
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body folding results in what folds?
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head fold
tail fold lateral body folds |
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when does the umbilical vesicle detach?
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6 wks
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what are three parts of the brain and brainstem?
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prosencephalon
mesencephalon rhombencephalon |
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germinal layers will dominate the next few cards
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have fun
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skin
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ectoderm
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epidermal glands
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ectoderm
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hair, nails
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ectoderm
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eye: lens, corneal epithelium
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ectoderm
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inner ear labyrinth
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ectoderm
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anterior pituitary
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ectoderm
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tooth enamel
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ectoderm
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neural tissue
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=neuroectoderm is a large, specialized derivative of ectoderm
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brain, brainstem and spinal cord
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neuroectoderm
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eye: retina, pigment epithelium, potic nerve part of iris
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neuroectoderm
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pas nervosa of pituitary gland
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neuroectoderm
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epithelium of alimentary canal
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endoderm
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parenchyma of pancreas and liver
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endoderm
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thyroid, parathyroid
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endoderm
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thymus
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endoderm
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lung and trachea
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endoderm
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middle ear epithelium
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endoderm
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urinary bladder and urethral epithelia
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endoderm
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vaginal epithelium
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endoderm
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endoderm forms epithelial surfaces, but the supporting elements of any given organ are derived from its ____
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mesoderm
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what are the regions of the mesoderm(6)?
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somite
intermediate mesoderm lateral plate mesoderm intraembryonic celom notochord septum transversum |
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somite differentiation begins from ____
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undifferentiated mesoderm
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early somite contains a _____
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somatocoele
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somite differentiation results in 2 layers, which are?
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dermomyotome
sclerotome |
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dermomyotome differentiates into what?
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dermatome and myotome
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vertebral bones and intervertebral disks from
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sclerotome
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dermis of skin, ventral skeletal muscle, doral skeletal muscle
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dermomyotome
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kidney, ureter and ductus deferens, gonads come from:
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intermediate mesoderm
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lateral plate mesoderm consists of what three mesoderms?
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somatic mesoderm (somatopleure)
intraembryonic celom splanchnic mesoderm (splanchonopleure) |
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bones, cartilage, fascia and other CT around periphery of body
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somatic mesoderm
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visceral smooth muscle, fascia and CT of viscera, associated vasculature
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splanchnic mesoderm
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what migrates with heart during embryo folding?
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septum transversum
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what separates thorax from abdomen early in development?
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septum transversum
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septum transversum participates in what developmen?
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venous cardiac
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the final derivative of the septum transversum is a part of what?
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central tendon of diaphragm
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neural crest
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arises from neural folds
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melanocytes of skin
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from neural crest
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all parts of peripherial nervous system, including ganglion cells, support cells, etc
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from neural crest
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in and near head can form bone, cartilage, and other CT of the pharyngeal arches
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from neural crest
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adrenal medulla
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from neural crest (NOT adrenal cortex)
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bulbar ridges (spiral spetum) of the heart
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from neural crest
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meninges
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from neural crest
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somitomeres
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like somites but without sclerotome
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bone and cartilage of head
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neural crest mesoderm
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connective tissues of branchial arches
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neural crest
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head muscles
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somitomeres
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