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211 Cards in this Set
- Front
- Back
This is made up of 10 billion to over 100 billion neurons that connect with 1,000 to 100,000 other neurons.
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The Nervous System
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The _______ and ________ work together as a "highly-integrated behavior controlling" mechanism that controls most of what we do.
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Nervous, Endocrine
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What are the two branches of the Nervous System?
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Central & Peripheral
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What are the two branches of the CNS?
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Brain & Spinal Cord
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What are the three branches of the PNS?
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Cranial & Spinal Nerves
Visceral Afferent (organs) Autonomic Nervous System (efferent & afferent) |
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What are the two branches of the ANS?
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Sympathetic & Parasympathetic
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What is the most basic functional unit of the nervous system?
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The Neuron
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What is made up of a cell body and it's processes?
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The Neuron
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What are the two processes of a neuron?
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Dendrites (sensory/afferent)
Axons (motor/efferent) |
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These bring info to the cell body
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Dendrites
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These send info out of the cell body
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Axons
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These offer support to the neurons and their processes, electrically insulate neurons from one another, and help maintain balance in the fluid environment of the neuron.
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Glial Cells
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These are more numerous than neurons by a factor of about 10 and account for about half the bulk of the central nervous system.
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Glial Cells
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This is an insulating layer of glial cells around nerve processes which aid in conduction velocity of nerve impulses
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Myelin
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These form myelin in the central nervous system.
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Oligodendrocytes
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These form myelin in the peripheral nervous system.
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Schwann Cells
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How much space does each neurolglial cell occupy?
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About a millimeter of length of a process.
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What are the junctions that are between cells that leave the neuron exposed to extracellular fluid and are important in the conduction velocity of nerve impulses?
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Nodes of Ranvier
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When does myelin form?
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After nerve processes have achieved an advanced stage of development.
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Why is it easier for young children to learn new things than adults?
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Because myelination of some nerve fivers does not occur until late childhood.
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What is made up of collections of cell bodies?
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Gray Matter
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What are collections of cell bodies inside the CNS called?
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Nuclei
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What are collections of cell bodies outside the CNS called?
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Ganglion
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What is made up of collections of axons?
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White Matter
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What are collections of axons inside the CNS called?
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Bundle, Column, Fasciculus, Funiculus Lemniscus, Tracts
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What are collections of axons outside the CNS called?
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Nerves
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These are a bundle of axons and/or dendrites from several neurons.
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Nerves
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These nerves are strictly afferent.
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Sensory Nerves
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These nerves are strictly efferent.
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Motor Nerves
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These nerves are composed of both afferent and efferent nerve processes.
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Mixed Nerves
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This the functional connections between neurons.
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Neural Synapse
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Where do axons end?
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Boutons Terminaux (terminal buttons)
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As there is no cytoplasmic continuity of neurons at the synapse, what is the .01 microns worth of space between 2 neurons called?
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Synaptic Cleft
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The initial neural impulse from a synapse is an ________ _______ _______.
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electrical chemical wave (which is transmitted in ONLY one direction).
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Boutons contain:
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synaptic vessicles
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What are chemicals within synaptic vesicles?
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Neurotransmitters
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These are released through the cell membrane into the synaptic cleft.
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Neurotransmitters
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This becomes ineffective after about a millisecond.
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Neurotransmitters
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This is a temporary depolarization of postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell. (Meant to get things going/moving)
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Excitatory Postsynaptic Potential
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This usually results from the flow of negative ions into the cell or positive ions out of the cell. (Potassium aids in slowing down)
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Inhibitory Postsynaptic Potential
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This contains a high concentration of synaptic vesicles containing a chemical transmitter that depolarizes the cell membrane below the synaptic cleft.
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Bouton
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A method of achieving or inhibiting action potential in the postsynaptic neuron, when one presynaptic neuron does not generate enough neurotransmitter.
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Summation
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Two or more successive impulses (from a single neuron) arrive at the postsynaptic neuron, exciting the neuron.
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Temporal Summation
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Simultaneous impulses from one or more axons to a dendrite or cell body, exciting the neuron.
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Spatial Summation
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What is the resting membrane potential inside the cell?
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-70 mV
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Outside the cell is ___x more ______ than inside the cell.
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10, positive
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What develops when a polarity reversal inside verses outside the cell takes place - caused by an exchange of ions across the cell membrane?
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Action Potential
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This is brought about by the flow of sodium from outside to inside the cell due to a stimulus opening ion channels.
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Action Potential
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What is the threshold for action potential?
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-50/-55 mV
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Why do we say that Action Potential is an all or nothing mechanism?
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Because the nerve will not fire/be excited unless it hits the threshold.
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At the peak of AP, the ______ of the cell becomes _______ with respect to the _______.
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Inside, positive, outside
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This is a cell's brief (0.8 msec) period of unresponsiveness.
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Refractory Period
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This is the period of time that the cell cannot be excited no matter how strong the stimulus is. It occurs during the 1msec of polarity change.
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Absolute Refractory Period
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This is the period of time when the cell can be excited because polarization has reached -50mV and a stronger stimulus is provided.
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Relative Refractory Period
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What is the enlargement of the spinal cord that is highly specialized for high-level functioning that is characteristic to humans?
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The brain
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What are the three sections of the brain?
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Hindbrain, Midbrain, Forebrain
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This is another term for the hindbrain.
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Rhombencephalon
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This contains the 4th ventricle which is the enlarged portion of the central canal of the spinal cord.
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Hindbrain
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What are the two sections of the hindbrain (rhombencephalon)?
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Myelencephalon & Metencephalon
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Where is the Medulla Oblongata?
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In the myelencephalon
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Where does the spinal cord merge into the brain?
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The Medulla Oblongata
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What two parts make up the Metencephalon?
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The Cerebellum and the Pons
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This is the posterior portion of the Metencephalon.
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Cerebellum
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What is the anterior portion of the metencephalon and a continuation of the medulla oblongata?
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Pons
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What is another term for the midbrain?
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Mesencephalon
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What connects the forebrain and the hindbrain?
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Midbrain (mesencephalon)
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Where is the cerebral aqueduct housed?
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Midbrain (Mesencephalon)
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What connects ventricles with the 4th ventricle?
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Cerebral Aqueduct
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What is another term for the forebrain?
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Prosencephalon
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What are the two divisions of the forebrain?
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Diencephalon & Telencephalon
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Where is the diencephalon located?
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Lateral to the 3rd ventricle.
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What are the two divisions of the diencephalon?
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Thalamus and Hypothalamus
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What is the principle relay and integration center for sensory information delivered to the telencephalon?
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Thalamus
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What influences and controls visceral activities, water balance, temperature, sleep, and metabolic functions?
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Hypothalamus
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What is the largest portion of the brain?
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Telencephalon
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What is the most anterior region of the brain - also known as the cerebrum?
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Telencephalon
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What are the 2 divisions of the cerebrum?
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Right and Left hemispheres
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This is a ridge or a bump on the cerebral cortex.
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Gyri
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Crack, depression, or fissure on the surface of the brain.
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Sulci
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What separates the two hemispheres of the brain?
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The Longitudinal Fissure
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Which sulcus separates the parietal and temporal lobes?
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Lateral Sulcus
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Which sulcus separates the frontal and parietal lobes?
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Central Sulcus
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What are the lobes named for?
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The cranial bones which overlie them (frontal, parietal, temporal, occipital)
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What is the deep lobe under the lateral fissure that functions with organs?
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Insular lobe
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Which lobe is anterior to the central sulcus?
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Frontal Lobe
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What is the area associated with the common motor pathways to skeletal muscles?
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Precentral Gyrus/Primary Motor Strip
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Where is the Broca's speech area?
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The left inferior frontal gyrus
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Which hemisphere is more heavily convoluted?
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The left inferior frontal gyrus
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What does damage to Broca's area cause?
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Apraxia
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Which area of the brain is important to speech production and language processing and composition?
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The left inferior frontal gyrus
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Which lobe is located posterior to the central fissure and superior to the lateral fissure?
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The Parietal Lobe
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The parietal lobe contains:
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Postcentral gyrus/Primary sensory strip and Inferior parietal gyri
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Where is the primary somatic sensory area?
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Postcentral gyrus
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Two divisions of Inferior Parietal Gyri
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Angular Gyrus & Supramarginal Gyri
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Functions for comprehension of the written word.
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Angular Gyrus
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Loss of ability to read
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Alexia
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Loss of ability to write
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Agraphia
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Which lobe is small and pyramidal in shape?
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Occipital Lobe
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Which lobe contains the primary visual area and visual association areas?
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Occipital Lobe
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What are the three divisions of the temporal lobe and how are they divided?
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Superior, middle, and inferior temporal gyri divided by 2 sulci that course parallel with the lateral sulcus.
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Where is the cortical center for hearing located?
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On the superior surface of the temporal lobe.
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What is the area of the brain that is associated with understanding and comprehension of language and where is it located?
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The Wernicke's area - located on the superior temporal gyri.
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What is the result of damage in the Wernicke's area?
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Wernicke's aphasia.
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What are the three types of fibers of the subcortical white matter of the cerebrum?
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Projection Fibers, Association Fibers, Commissural Fibers
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What type of white matter fiber conveys impulses from remote regions to and from the cerebral cortex?
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Projection Fibers
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There are both afferent and efferent fibers sending signals to and from the cerebral cortex that enter the white matter in fan shaped bundles that converge near the brain stem. What are the fan shaped bundles and what are they when they converge?
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Corona radiata, internal capsule
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The ______ _______ is flanked medially and laterally by gray matter called ______ _______ .
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internal capsule, basal ganglia
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What type of white matter fibers interconnect various cortical regions in the same hemisphere?
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Association fibers
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The _______ fibers (association fibers) connect in adjacent convolutions.
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Short
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The ______ (fibers) interconnect cortical regions within the same hemisphere.
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Long
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What are the three types of long association fibers?
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Uncinate Fasciculus, Arcuate Fasciculus, Cingulum
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Which long association fiber connects the frontal gyri to the anterior part of the temporal lobe?
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Uncinate Fasciculus
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Which long association fiber connects the Broca's and Wernicke's areas?
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Arcuate Fasciculus
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Which long association fiber connects the frontal and parietal lobes to parts of the temporal lobe?
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Cingulum
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What white matter fibers interconnect the corresponding cortical regions of the 2 hemispheres?
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Commissural Fibers
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What are the two types of Commissural fibers?
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Corpus Callosum & Anterior Commissure
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What are the masses of gray matter within the cerebrum?
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Basal Ganglia
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What are the two parts of basal ganglia?
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Caudate Nucleus and Lenticular Nucleus
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What are the two divisions of the Lenticular Nucleus?
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Putamen and Globus Pallidus
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What receives input from nearly all parts of the cerebral cortex - especially from the motor area?
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Basal Ganglia
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______ ______ receives radiation fibers from the _______ in addition to important afferent fibers from _______ _________ cells in the ________ _______ of the _____________.
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Basal Ganglia, thalamus, dopamine-synthesyzing, substantia nigra, mesencephalon
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This is important in regulating complex motor functions such as posture, locomotion, balance, etc.
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Basal Ganglia
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What is inhibitory in nature, instrumental in decreasing muscle tone, and aids in coordinating the motor behavior of muscle groups?
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Basal Ganglia
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What is part of the hind brain and receives input about length and tension of almost every skeletal muscle?
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Cerebellum
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The cerebellum compensates for cortically induced movements so they are more _______ ________.
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smoothly coordinated.
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The _________ is highly integrated and capable of tracking muscle and limb movements.
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Cerebellum
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There are about _____ times more _____ fibers entering than ______ fibers leaving the cerebellum.
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40, afferent, efferent
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The ________ is connected to the brain stem, but is NOT considered part of it.
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Cerebellum
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This is the term used to designate the Diencephalon, Mesencephalon, Pons, and Medulla Oblongatta.
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The Brain Stem
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What contains the nuclei for most of the cranial nerves as well as centers associated with regulation of visceral, endocrine, behavioral, and metabolic functions?
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The Brain Stem
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The ______ ______ contains a number of __________ and _________ nerve tracts and nuclei that comprise major integrating centers for both _______ and ______ functions.
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Brain stem, ascending, descending, sensory, motor
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What are the 5 functions of the cerebral cortex?
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thought, voluntary movement, language, reasoning, perception
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What are the 3 functions of the cerebellum?
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movement, balance, posture
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What are the 3 functions of the brain stem?
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breathing, heart rate, blood pressure
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What are the 5 functions of the hypothalamus?
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emotions, hunger, thirst, circadian rhythms, body temperature
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What are the 2 functions of the thalamus?
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sensory integration, motor integration
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These are important in the production and circulation of cerebrospinal fluid.
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Ventricles
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How many ventricles are they and what are they called?
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Four: Lateral (2), 3rd ventricle, 4th ventricle
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What are the bundles of cells in the ventricles where CSF is produced?
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Choroid Plexus
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What are the three layers of nonnervous connective tissue called? What is each layer called?
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Meninges:
Dura Mater, Arachnoid Mater, Pia Mater |
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The spaces between the meninges contain _____ which ______, ______, and _____ the brain and spinal cord.
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CSF, moistens, lubricates, protects
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What is the outermost layer of the meninges?
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Dura Mater
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What does "dura mater" mean?
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Tough Mother
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What are the two layers of dura mater?
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Periosteal & Meningeal
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What are the two meningeal layer forms?
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Falx cerebri & Tentorium cerebelli
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Which meningeal layer separates the 2 cerebral hemispheres down the midline?
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Falx cerebri
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Which meningeal layer separates the cerebellum from the cerebrum?
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Tentorium cerebelli
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Which meninges layer resembles a spider web and is separated from Dura mater by a thin layer of fluid (CSF) in the subdural spacce?
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Arachnoid Mater
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How is the Arachnoid Mater separated from Pia Mater?
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Subarachnoid spaces
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What are the projecctions that reabsorb CSF so that pressure doesn't build up?
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Arachnoid Granulations
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What is the inner most layer of the meninges?
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Pia Mater
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What is the thin, mesh-like membrane that closely follows the entire surface of the brain, running down into the fissures of the cortex?
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Pia Mater
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Cerebrospinal Fluid begins in the ______ ______, passes into the _____ and from there to the ______, where it diffuses by means of small ______ into the _________ ______. It continues to ________ ______ the brain and is finally ________ by an elaborate _______ system that drains the blood from the brain.
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lateral ventricles, third, fourth, apertures, subarachnoid space, circulate around, absorbed, veonous
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CSF flows into the subarachnoid space through the __________ __ _________ in the roof of the 4th ventricle.
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Foramen of Magendie
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The lower end of the brain stem is continuous with what?
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The spinal cord
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This extends from the top of the first cervical vertebra to the bottom of the first lumbar vertebra.
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Spinal cord
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The internal structure of the spinal cord is a central core of ______ ______ surrounded by _______ ______.
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gray matter, white matter
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The entire spinal cord has a central canal - in adults the canal is frequently _________.
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obliterated
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Gray matter consists of what 2 crescent shaped bodies?
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Ventral Horn (Motor) and Dorsal Horn (Sensory)
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The ventral horn and the dorsal horn are joined at the _______ by a _______ ________ of gray matter.
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midline, transverse fissure
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What has a shape of a butterfly or the letter h?
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Gray matter
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The lateral horns of gray matter are for what?
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The autonomic nervous system
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What are the columns of the spinal cord?
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Ventral, Dorsal, Lateral
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Which column of the spinal cord contains motor nerve cells?
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Ventral
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Which column of the spinal cord contains mostly sensory nerve cells?
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Dorsal
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Which column of the spinal cord contains cells of the autonomic nervous system?
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Lateral
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How are organic acids handeled by the proximal tubule?
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Useful metabolic substrates are reabsorbed by proximal tubule and others are secreted.
Acetate, lactate, citrate, and mono- and dicarboxylic acids (Krebs cycle intermediates) are normally reabsorbed completely. Under abnormal conditions (diabetic ketoacidosis and lactic acidosis) plasma threshold of some of these substances is exceeded. |
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What does each funiculus contain?
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1. Ascending fiber tracts transmitting visceral and proprioceptive info to the subcortical motor centers.
2. Descending tracts from the higher motor centers. 3. Short intersegmental fibers that mediate reflexive behavior. |
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What does gray matter have that white matter does not?
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Cell bodies
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Is white and gray matter exactly the same all throughout the spinal cord?
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No
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What includes any neuron or nerve cell process located outside the bony confines of the skull and vertebral column?
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The Peripheral Nervous System
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What two types of nerves are included in the Peripheral Nervous System?
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Cranial and Spinal
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The PNS is made up of ___ types of fibers.
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7
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How many pairs of cranial nerves are they and what are they numbered for?
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12, according to their emergence from the brain stem
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What do the names the cranial nerves reflect?
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Function, structure, or distribution
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What is the area of the brain where a cranial nerve appears?
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Superficial origin
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All nerves leave the cranium except for?
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CN 1 and 2
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Are all of the cranial nerves necessary for speech production or reception?
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No
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 1?
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Sensory, Olfactory, Telencephelon, Smell
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 2?
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Sensory, Optic, Diencephalon, Vision
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 3?
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Motor, Oculomotor, Midbrain, Eyelid movement and muscles of the eye
ex: Like crossing eyes - moves the eye in all directions and raises the upper eyelid |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 4?
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Motor, Trochlear, Midbrain, Eye movement (down & outward)
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 5?
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Sensory & Motor, Trigeminal, Pons (facial skin, oral cavity, nasal cavity, tongue)
Sensory: superficial and deep structures of the face, mouth, and lower jow Motor: muscles of mastication, soft palate, the mylohyoid and anterior belly of the digastric - 3 branches - opthalmic, maxillary, mandibular |
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What are the three motor branches of the trigeminal nerve (#5)?
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Opthalmic (eye, nose, scalp)
Maxillary (lower eyelid, mouth, teeth) Mandibular (largest branch) |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 6?
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Motor, Abducent, Pons, Eyeball movement (lesions cause double vision)
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 7?
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Motory & Sensory, Facial, Pons (innervation from stapedious muscle of middle ear, stylohyoid, and posterior belly of digastricus
Motor: muscle movement of face Sensory: sensations of tongue and soft palate |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 8?
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Sensory, Vestibulocochlear/Acoustic, Pons, Hearing and Balance
** Important for speech production |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 9?
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Sensory & Motor, Glassopharyngeal (Tongue), Medulla
Sensory: taste and sensation Motor: pharynx and salivation |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 10?
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Sensory & Motor, Vagus (wandering course, longest nerve), Medulla
Sensory: sensation to ear, pharynx, larynx, viscera Motor: movement to muscles of pharynx, larynx, tongue and smooth muscles of the viscera |
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 11?
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Motor, Accessory, Medulla, Movement of uvula, levator veli palatini, and sternocleidomastoid
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What is the type (sensory or motor), name, origin, and function of Cranial Nerve 12?
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Motor, Hypoglossal, Medulla, Musculature of the tongue
** Very important to speech |
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How many pairs of spinal nerves are there?
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31:
-8 cervical -12 thoracic -5 lumbar -5 sacral -1 coccygeal |
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Where does the first cervical spinal nerve originate?
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From between the occipital bone and the atlas.
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Where do the spinal nerves leave through?
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The intervertebral foramen.
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Pairs of spinal nerves emerge from the _____ ____ in _______ and ______ roots which combine to form a complete ______ ______.
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spinal cord, ventral (efferent), dorsal (afferent), spinal nerve
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What is the area of the skin supplied by a single, specific, spinal nerve root? It is a cutaneous distribution of sensory fibers.
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Dermatomes
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Shingles appear in lines of _________.
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Dermatones
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What is it called when researchers map areas of the brain that are functionally homogenous regions of the brain?
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Cortical Mapping
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A ___________ is often used to show the body representation in both the motor and sensory cortices.
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homunculus
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What is the division of the peripheral nervous system that supplies the smooth muscles and glands throughout the body?
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Autonomic Nervous System
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The entire Autonomic Nervous system is afferent or efferent?
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Efferent
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The autonomic nervous system is divided into what two systems that work together to maintain a relatively constant internal body environment?
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Sympathetic and Parasympathetic
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What system prepares the body for emergencies or periods of excitement and is responsible for internal adjustments to stress or crises? (Fight or flight)
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Sympathetic system
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What system acts in antagonism to the effects of the sympathetic division and acts to conserve body resources and/or reduces internal activity?
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Parasympathetic system
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For 90% of right handed people, the _____ cerebral hemisphere is specialized for language, handedness, analytic thought processes, and certain types of memory.
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Left
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The left hemisphere is dominant ina bout 64% of ______-handed people; and about 20% are _____-hemisphere dominant.
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Left, right
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In about 60% of ambidextrous people the ______ hemisphere is dominant where 30% had equal dominance among the 2 hemispheres.
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Left
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The _____ hemisphere functions in most aspects of language, handedness, calculation, and memory of 90% of the population.
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left
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The ______ hemisphere specializes in perception by the sense of touch, spatial conceptualization, and nonverbal language. It is also instrumental in the way we listen to music and see works of art.
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Right
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Children do not have a dominant hemisphere until the _____ year of life.
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2nd
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T/F
Cutting the corpus callosum has extremely adverse affects. |
False - in a surgery in the 40s, there were no adverse effects noticed which cause many people to believe that the 2nd hemisphere is a back up in case something happens to the dominant hemisphere.
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