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12 Cards in this Set

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  • Back
Name the 2 syndromes/disease that are examples of demyelinating neuropathy.
Guillan-Barre syndrome & Charcot Marie Tooth Dz
Which condition is onion bulbing and hypertrophic nerves a part of?
Charcot Marie Tooth Dz
There are three types of myopathic muscle disorders (as opposed to neurogenic). What are they?
1) dystrophic (degenerative)
2) inflammatory
3) congenital
Characterize the difference between Duchenne's and Becker's dystrophinopathies.
Duchenne- more severe, early onset, rapid progression

Becker's- less severe, late onset, slow progression
If someone has sensory disturbance, it has to be in a nerve. DISTAL/PROXIMAL weakness with numbness, decreased reflex and dyesthesia.

With myopathic disorder, you’ll see DISTAL/PROXIMAL muscle weakness
except for myotonic dystrophy! Which is DISTAL/PROXIMAL muscle weakness.
DISTAL, PROXIMAL, DISTAL
Effects of hemicord (brown-sequard) lesion
- IPSI loss of fine touch/vibration below level (dorsal columns)
- IPSI loss of UMN below level (corticospinal tract)
- CONTRA loss of pain/temp (Spinothalamic tract)
Effects of anterior spinal artery infarct
- BILATERAL loss of STT below level
- BILATERAL upper motor neuron weakness below level (CST)
- BILATERAL LMN damage (flaccid paralysis) at the segmental level
- preservation of Dorsal column system
Effects of syringomyelia (cyst in central canal)
- early on ==> segmental loss of pain/thermal sense (STT)
- later on as tumor gets larger, loss of LMN in anterior horn bilaterally
Effect of Tabes Dorsalis and what is its common cause?
DC knocked out; tertiary syphilis
What does combined system degeneration/Vit B12 deficiency do?
loss of DC and lateral CST
- leaves STT intact
In other words, loss of myelin in CST and DC long tracts - combined system (sensory and motor) degeneration
Which long tract disease causes loss of both upper and lower motor neurons without any sensory involvement?
ALS = amyotrophic lateral sclerosis
(motor neuron disease)
Which condition causes loss of just anterior horn cells (LMN) leading to flaccid LMN weakness?
poliomyelitis and spinal muscular atrophy (SMA)