Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
58 Cards in this Set
- Front
- Back
Three divisions of the PNS and what they innervate
|
Somatic-skeletal
Autonomic-smooth, glands, cardiac Enteric- enteric plexuses |
|
ECM of PNS
|
peripheral nerves; three connective tissue sheaths
|
|
What are the three connective tissue sheaths?
|
Endoneurium
perineurium epineurium |
|
Resident cells of PNS
|
Neurons-transmit impulses
Neuroglial cells- Schwann cells |
|
What is the principle of dynamic polarization?
|
The information flow is unidirectional
|
|
GSA=
impulses from? |
general somatic afferent
skin, bone, skeletal muscle, joints, ligaments, tendons... |
|
GVA=
impulses from? |
general visceral afferent
viscera including blood vessels |
|
GSE=
Innervate? |
general somatic efferent
skeletal muscle |
|
GVE=
innervate? |
general visceral afferent
smooth and cardiac muscle and most glands |
|
Which fiber type is the largest in diamater and myelinated?
|
Type A; GSE, GSA
|
|
Fiber type:
preganglionic autonomic, myelinated |
Type B
|
|
Fiber type:
postganglionic sympathetics, unmyelinated (dorsal Root-pain,temp, mechanoreception) |
Type C
|
|
Function of the nervous system:
|
communication;
|
|
Function of PNS:
|
keep other tissues of the body in communication with the central nervous system
|
|
What makes up the CNS? PNS?
|
CNS=brain and spinal cord
PNS=ganglia, nerves, nerve endings, organs of special senses |
|
The signaling properties of thhe nervous tissue express two fundamental attributes of protoplasm?
|
1. excitability-create APs
2. conductivity- propagaion of APs |
|
Cell body of a neuron
|
soma
|
|
cytoplasm of a neuron
|
perikaryon
|
|
Two types of radiating cell processes?
|
axon-transmission
dendtrite-reception |
|
Type of neuron that has only one process, an axon.
|
Pseudounipolar
|
|
Where are pseudounipolar neurons found?
|
Sensory ganglia associated with dorsal roots and of certain cranial nerves
|
|
Bipolar neurons differentiate into what?
|
pseudounipolar neurons
|
|
Type of neuron with two processes, both axons.
|
bipolar neurons
|
|
Neurons with three or more processes, one of which is an axon and the others dendrites
|
multipolar neurons
|
|
Where are the cell bodies of bipolar neurons found?
|
retina, vestibular and acoustic ganglia. fetus
|
|
Where are the cell bodies of multipolar neurons found?
|
central nervous system and autonomic ganglia
|
|
An axon plus one or two coverings
|
nerve fiber
|
|
all nerve fibers have what?
|
Sheath of Schwann and some have a myelin sheath
|
|
Points at which an axon is devoid of myelin
|
node of ranvier
|
|
deceptive, false interruptions are the incisures of what
|
clefts of Schmidt-Lantermann
|
|
A spongy framework visible after myelin extraction during processesing is what?
|
neurokeratin network
|
|
Nerve fibers are organized into several bundles known as _____. the nerve fibers are surrounded by a delicate connective tissue called the ______
|
fasicles
endoneurium |
|
Immediately surrounding the fascile is a dense connective tissue composed of perineurial cells, longitudinally arranged collagen fibrils and numerous blood and lymphatic vessels.
|
Perineurium
|
|
The fascicles are bound by this into a nerve trunk; dense connective tissue containing collagen and elastic fibers, fat, and blood vessels.
|
epineurium
|
|
70% of myelin is ?
Composed of what two major things? |
lipid; cholesterol and cerebroside
|
|
Major dense lines are caused by the fusion of the __ surface of the Schwann PM. What protein is found there?
|
P; Myelin Basic protein
|
|
Intraperiod lines are the fusion of the __ surfaces of the Schwann PM. What protein is found there?
|
E; Protein zero (Po)
|
|
Nerve impulse conduction can be blocked by what things?
|
cold, heat, pressure on the nerve fiber
anesthetics-complete blocking |
|
nerves of various sizes often accompany blood vessels and this arrangement is referred to as a
|
neurovascular bundle
|
|
Always short, highly branched, and conduct graded potentials?
|
Dendrites
|
|
What type of graded potentials can a dendrite conduct?
|
EPSP
IPSP |
|
Long, can be short, collateral branches, terminal boutons, conduct action potentials?
|
Axon
Axolemma=PM Axoplasm=cytoplasm |
|
What is responsible for axonal transport?
|
Microtubules
|
|
Where AP is started? never myelinated
|
Trigger zone
|
|
RER + free polysomes=
|
nissyl bodies
|
|
What makes up the neurofibrils?
|
MTs and neurofilaments
|
|
What is absent in the axon hillock and axon?
|
RER
|
|
Where is the locations of the voltage gated NA channels?
|
all over the axon but only active at the Nodes of Ranvier, the myelin prevents them from opening.
|
|
What type of collagen?
A.Epineurium B.Perinurium C.endoneurium |
A.type I
B.type I C. Type III, reticular fibers |
|
Which connective tissue sheath has some tight junctions
|
perineurium
|
|
Schwann cells are of what germ layer derivative?
|
neural crest
|
|
Schwann cells contain what IF?
|
GFAP
|
|
What is the membrane resting potential of a neuron?
|
-70mV
|
|
Where do graded potentials summate?
|
At trigger zone of inital segment
|
|
What is the threshhold membrane potential
|
-50mV; will propogate an AP in an all or none response
|
|
What type of conduction is in myelinated axons?
|
saltatory
|
|
What restores the resting membrane potential?
|
Na/K pumps
|
|
What type of conduction is in unmyelinated axons?
|
continuous; requires a lot of ATP and is very slow.
|