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143 Cards in this Set

  • Front
  • Back

Neuroglia

Glial cells. Supports and protect neurons. These outnumber neurons 10:1. No nerve transmission.


Myelinated axons

Conduct impulses faster than un_______ axons. Form by different glial cells depending on location. Ogliodendrocytes are in the brain and spinal cord, and Schwann cells are in the peripheral nerves.

Nodes of Ranvier

Gaps in the myelin sheath that allow faster nerve impulse conduction due to 'skipping'.( Saltatory conduction).

Gaps in the myelin sheath that allow faster nerve impulse conduction due to 'skipping'.( Saltatory conduction).

Saltatory Conduction

Rapid means of conduction an action potential along myelinated axons. Depolarization only happens at the Nodes of Ravier.Allow vision and fine motor skills. Multiple sclerosis

Rapid means of conduction an action potential along myelinated axons. Depolarization only happens at the Nodes of Ravier.Allow vision and fine motor skills. Multiple sclerosis

Multiple sclerosis

Damages to myelin sheath that slows the muscle response. Muscles don't respond to what brain wants to do.

Organization of the Nervous System

Anatomical, Direction of impulses, and function.

Central Nervous System

Anatomical nervous system. Brain and spinal chord. Along the central axis of the body.

Peripheral nervous system

Anatomical Nervous System.Extends outward from the central axis toward the periphery of the body. Cranial nerves originate directly from the brain. Spinal nerves emerge from the spinal chord.

Afferent Nerves

Direction of impulses. Take impulses to the CNS. Sensory nerves .

Efferent Nerves

Direction of impulses. Takes impulses away from the CNS. Motor nerves to target organs. May carry fibers that are sensory, motor, or both signals.

Somatic Nervous System

Function. Actions under conscious, or voluntary control. Impulses sent mainly to skeletal muscle.

Autonomic Nervous System

Controls and coordinates involuntary functions. Ex. Slowing of the heart rate in response to an increased blood pressure. Impulses send to smooth and cardiac muscles and glands.

Neuron Function

Resting membrane potential. High Na outside, low inside. High K+ inside, low outside.

Action Potential

Nerve impulse. Depolarization and repolarization

Depolarization

When the neuron receives a stimulus. Na+ channels open in the membrane. Na+ flows into cell by passive diffusion. The inside of the cell becomes +.

When the neuron receives a stimulus. Na+ channels open in the membrane. Na+ flows into cell by passive diffusion. The inside of the cell becomes +.

Repolarization

Na+ channels close, K+ channels open as the K+ flows out of the cells. Inside of the cell is negative again, bringing it back to resting potential.

Na+ channels close, K+ channels open as the K+ flows out of the cells. Inside of the cell is negative again, bringing it back to resting potential.

Generation of an Action Potential

Na+/K+ pump restores the ions on the correct side of the membrane. Outside is + and inside is -. Maintained by the pump by pumping Na+ from the inside of a neuron to the outside, and K+ from the outside to the inside. Active transport.

Threshold Stimulus

Stimulus that is strong enough to make the neuron response and cause completely depolarization. The all or nothing principle.

Once an action potential in generated

Depolarization spreads down membrane in a wave. "Nerve impulse".

Communal nerve

A bundle of axons

Resting membrane potential

Difference in electrical charge across the membrane. From differences in distribution of positive and negative ions including potassium, proteins, and other charged ions.

Muscle cells

modified to respond to electrical signals.

electricity

All communication from your body comes from ___________.

Nervous system

Look at slide 8

Action potential graph

Threshold Stimulus and sustained threshold stimulus

Synaptic Transmission

Communication between neurons. Involves the synapse, the synaptic cleft, presynaptic neuron and postsynaptic neuron.

Synapse

Junction between two neurons, or a neuron and a target cell.

Junction between two neurons, or a neuron and a target cell.

Synapse

Synaptic cleft

Gap between adjacent neurons

Presynaptic neuron

Brings the depolarization wave to the synapse, and releases the neurotransmitter

Postsynaptic neuron

Contains receptors for the neurotransmitter.

Step 1 in the Neurotransmitter Action

Neurotransmitter molecules are synthesized from precursors under the influence of enzymes .

Neurotransmitter molecules are synthesized from precursors under the influence of enzymes .

Step 2 in the Neurotransmitter Action

Neurotransmitter molecules are stored in vesicles

Neurotransmitter molecules are stored in vesicles

Step 3 in the Neurotransmitter Action

Neurotransmitter molecules that leak from vesicles are destroyed by enzymes

Neurotransmitter molecules that leak from vesicles are destroyed by enzymes

Step 4 in the Neurotransmitter Action

Action potential causes vesicles to fuse with the presynaptic membrane and release their neurotransmitter molecules into the synapse.

Action potential causes vesicles to fuse with the presynaptic membrane and release their neurotransmitter molecules into the synapse.

Step 5 in the Neurotransmitter Action

Released neurotransmitter molecules bind with autoreceptors and inhibit subsequent neurotransmitter release .

Released neurotransmitter molecules bind with autoreceptors and inhibit subsequent neurotransmitter release .

Step 6 in the Neurotransmitter Action

Released neurotransmitter molecule bind to postsynaptic receptors.

Released neurotransmitter molecule bind to postsynaptic receptors.

Step 7 in the Neurotransmitter Action

Released neurotransmitter molecules are deactivated either by reuptake or enzymatic degradation.

Released neurotransmitter molecules are deactivated either by reuptake or enzymatic degradation.

Acetylcholinesterase

Mono-amine oxidase (MAO). Antidepressants prevent breakdown and reabsorption of neurons. Degrades the synaptic transmitters. Either excitatory or inhibitory on target cell, depending on the location. Main transmitter for the parasympathetic nervous system. Neurotransmitter.

Examples of acetylcholinesterase

Excite motor neurons, inhibits heart rate.

Catecholamines

Excitatory neurotransmitter. Norepinephrine and Epinephrine (basically the same). Produced in top concave portion of the kidneys. Made in the adrenal gland in the sympathetic nervous system.

Dopamine

Type of neurotransmitter that is involved with automatic functions and muscle control. Found in the brain. Associate with tremors in Parkinson's disease .

Parkinson's Disease

Causes tremors. Lack of dopamine neuron function.

Gamma-aminobutyric acid (GABA)

Type of inhibitory neurotransmitter in the brain.

Glycine

Type of inhibitory neurotransmitter in the spinal cord

Valium

Type of glycine tranquilizer that works by increasing GABA effects on brain. Tranquilization leads to sedation.

Central Nervous System

Consist of the spinal and cord and brain, which includes the cerebrum, cerebellum, diencephalon, and the brain stem.

Cerebrum

Part of the brain responsible for higher order behaviors including learning, intelligence, and awareness. Consists of gyri and sulci, longitudinal fissure, gray matter, and white matter. Telecephalon.

Cerebrum

Folded to allow more surface area to allow more neurons, to allow more synapses, to allow more neural ability

Folded to allow more surface area to allow more neurons, to allow more synapses, to allow more neural ability

Frontal lobe

Lobe of the cerebrum where voluntary movement planned, psychomotor skills, motor cortex.

Lobe of the cerebrum where voluntary movement planned, psychomotor skills, motor cortex.

Parietal lobe

Location of pain, touch, temperature, and perception in the cerebrum. Mostly sensory information.

Location of pain, touch, temperature, and perception in the cerebrum. Mostly sensory information.

Parietal ; frontal

________ lobe senses pain in the hand, then sends signals to the _______ lobe that figures out what needs to be done to remove pain from the hand.

Occipital lobe

Visual interpretation in the cerebrum

Visual interpretation in the cerebrum

Temporal lobe

Auditory, behavior, and memory in the cerebrum

Auditory, behavior, and memory in the cerebrum

Cerebellum

Located caudal to the cerebrum. The area of the brain responsible for coordinated movement, balance, posture, and complex reflexes

Located caudal to the cerebrum. The area of the brain responsible for coordinated movement, balance, posture, and complex reflexes

Hypoplastic Cerebellum

Motor coordination that is not formed correctly. Subject wobbles when they move.

Diencephalon

Passageway between the brain and the cerebrum. Includes the hypothalamus, thalamus, and the pituitary

Passageway between the brain and the cerebrum. Includes the hypothalamus, thalamus, and the pituitary

Thalamus

Regulates sensory inputs to the cerebrum (bouncer)

Regulates sensory inputs to the cerebrum (bouncer)

Hypothalamus

Interface between the nervous system and the endocrine system.

Interface between the nervous system and the endocrine system.

Pituitary

Endocrine, the master gland. Rests in the pituitary fossa. Produces hormones that produces the body's ciruclation. Growth hormones, water intake, etc.

Brain stem

Connection between the rest of the brain and the spinal cord. The most primitive part of the brain. Include the medulla oblongata (caudal part), pons, and midbrain. Basic support functions of the body including heart beat, respiration, etc. Many cranial nerve originate here.

Brain stem

Meninges

Connective tissue layer that surrounds the brain and spinal cord. Composed of three layers: dura mater, arachnoid, and pia mater.

Gray matter

Part of the cerebrum located in the cerebral cortex, which is the outer layer of the brain that consists of neuron cell bodies.

White matter

Communication in the cerebrum, how all the signals travel from the neurons to all the places they have to go. Have myelinated axons and the corpus callosum

Myelinated axons

Fibers beneath the cortex in white matter.

Corpus callosum

Fibers that connect the two halves of the cerebral cortex and allow communication in white matter.

Midbrain

Controls basic autonomic functions in the brain stem.

Outline of skull layers

Cerebrospinal Fluid

Circulates around the brain (subarachnoid space), within ventricle system, and within the spinal canal. Clear, colorless, and has low protein. Made by the choroid plexus in 4th ventricle.

Circulates around the brain (subarachnoid space), within ventricle system, and within the spinal canal. Clear, colorless, and has low protein. Made by the choroid plexus in 4th ventricle.

Functions of the cerebrospinal fluid

Protection and buoyancy, circulate nutrients, and removes waste products.

Blood Brain Barrier

Separates body's blood supply in the brain from the nervous tissue. Capillary walls that have no fenestrations. Prevent many drugs, proteins, ions, and other molecules from readily passing from the blood into the brain.

Capillary walls in the brain

Consists of endothelial cells connected by tight junctions. Covered process of glial cells.

Most capillaries in the body

Brain capillaries

12

___ Nerve pairs in the brain originate directly from the brain. Each may carry sensory signals, motor signals, or both.

Cortex

The outer part of the spinal cord that consists of white matter (axons).

Medulla

Inner part of the spinal cord (gray matter). Includes the central canal which contains CSF. Middle portion where the neurons are.

Inner part of the spinal cord (gray matter). Includes the central canal which contains CSF. Middle portion where the neurons are.

Dorsal nerve roots

Contain incoming sensory (afferent) fibers. Emerges between each pair of adjacent vertebrae.

Contain incoming sensory (afferent) fibers. Emerges between each pair of adjacent vertebrae.

Ventral nerve roots

Contain motor (efferent) fibers. Emerges between each pair of adjacent vertebrae.

Contain motor (efferent) fibers. Emerges between each pair of adjacent vertebrae.

Ganglion

Collection of neurons .

Somatic reflexes

Reflex that involves the contraction of skeletal muscles

Autonomic reflexes

Reflexes that regulate smooth muscle, cardiac muscle, and endocrine glands.

Contralateral reflex

Reflex that starts on one side of the body and travels to the opposite side.

Ipsilateral reflex

Reflex where the stimulus and response are on the same side of the nody.

Relfex arc

A basic process that all reflexes have. see slide 29.

Stretch reflex

includes a monosynaptic reflex arc, and sensory receptor is a muscle spindle, which when stretched, sends a signal causing the muscle to contract. Example is the patellar reflex. Antagonist muscle gets signaled to relax. Slide 31.

Monosynaptic reflex arc

Part of the stretch reflex. Involves a sensory neuron and a motor neuron. No interneurons involved.

Crossed Extensor Reflex

Contralateral reflex. Afferent sensory neuron synapses with interneurons that transmit information to the opposite side of the spinal cord. Causes contraction of opposite extensor muscles. Both sides of the body.

Crossed extensor reflex

When you step on a nail and raise your foot, the unaffected leg bears the weight.

Hearing

Converts vibration of air molecules into nerve impulses are that interpreted by the brain as sound.

temporal

Ear structures are mostly located in the


________ bone.

External ear

Part of the ear that is a funnel to collect sound wave vibrations and direct them into the rest of the ear. Have the pinna and auditory canal. Made of elastic cartilage.

Middle ear

Part of the ear that amplifies and transmits the vibrations to the inner ear. Has the tympanic membrane and auditory ossicles.

Inner ear

Contains the sensory receptors that convert the mechanical vibrations to nerve impulses. Also has receptors for equilibrium part of the inner ear.

Cochlea

Sensory receptor in the inner ear that converts the mechanical vibrations to nerve impulses. Cochlear duct. Involves the endolymph and sensory hair cells including "Organ of Corti" and Cochlear Nerve. Surrounded by Perilymph (U-shaped tube)

Sensory receptor in the inner ear that converts the mechanical vibrations to nerve impulses. Cochlear duct. Involves the endolymph and sensory hair cells including "Organ of Corti" and Cochlear Nerve. Surrounded by Perilymph (U-shaped tube)

Sensory hair cell

Sit on the basilar membrane and tops the tectorial membrane in the cochlea.

Step 1 in sound transmission

Sound waves are collected by the pinna, and are funneled into the auditory canal.

Step 2 in sound transmission

Sound waves vibrate the tympanic membrane, which vibrates the three auditory ossicles attached to membrane. Ossicles vibrate the oval window at the entrance of the cochlea.

Step 3 in sound transmission

Vibration of the oval window vibrates the fluid in the cochlea. Sensory hairs moved up and down by fluid wave, and tips of hair hit tectorial membrane and get bent.

Step 4 in sound transmission

Bending of the hairs causes cochlear nerve to send a nerve impulse (auditory signal) to the brain.

Equilibrium

Maintains balance by keeping track of the position and movements of the head. Involves ________ receptors, information from the eyes, and proprioceptors throughout the body. has receptors in the vestibule and semicircular canals.

Vestibule

Part of the inner ear involved in equilibrium that has receptors with linear motion and static head position. Have the untricle and saccule. Has gelatin with otoliths on top of sensory hairs.

Part of the inner ear involved in equilibrium that has receptors with linear motion and static head position. Have the untricle and saccule. Has gelatin with otoliths on top of sensory hairs.

Untricle and saccule

Patches of sensory hair in each area of the vestibule.

Semicircular canals

Part of the inner ear involved in equilibrium that has receptors. Has rotational movement. Has 3 fluid tubs arranged in the X, Y, and Z axis. Has the ampulla, but doesn't have otoliths.

Part of the inner ear involved in equilibrium that has receptors. Has rotational movement. Has 3 fluid tubs arranged in the X, Y, and Z axis. Has the ampulla, but doesn't have otoliths.

Ampulla

Sensory hair structure in each area of the semicircular canals.

Nerve supply

Vestibulocochlear nerve.

Eye

Various structures to control and focus light onto sensory photoreceptors. They convert electromagnetic energy into nerve impulses. Has the optic nerve.

externally ; internally

Both eyelids lined by haired skin ___________ and mucous membrane ____________



Superior palpebra

More mobile of the eyelids and has cilia.

Palabrae

Superior palpebra, medial commisure, palpebral fissure, inferior palpebra, lateral commisure.

Superior palpebra, medial commisure, palpebral fissure, inferior palpebra, lateral commisure.

Lacrimal glands

Makes and secretes tears, and washes the surface of the eye. Drains into the nasolacrimal duct (nasal passage).

Makes and secretes tears, and washes the surface of the eye. Drains into the nasolacrimal duct (nasal passage).

Nictating membrane

Cartilage plate. Lies medial between palpebrae and globe (eyeball). Has lymph modules and accessory lacrimal gland.

External fibrous coat

Layer of the globe (eyeball) including the cornea and sclera. Most superficial layer that completely surrounds the globe. Dense c.t.

Middle vascular coat

Uvea, layer of the globe (eyeball) including the iris, choroid, and ciliary body. Provides nourishment to the globe, controls pupillary diameter, and controls the shape of the lens.

Internal coat

Nervous tunic. Layer of the globe (eyeball) that includes the retina, and the nerves and vessels associated with it.

Limbus

Corneroscleral junction in the external fibrous coat.

Cornea

Takes up 1/4 of the anterior portion of the external fibrous coat. Transparent and avascular.

Sclera

Takes up 3/4 of the posterior portion of the external fibrous coat. Opaque and has elastic fibers.

Takes up 3/4 of the posterior portion of the external fibrous coat. Opaque and has elastic fibers.

Iris

Have two layers of smooth muscle, the circular (constrict)  and radial (dilate), in the middle vascular coat of the eye. Located between the cornea and lens, controls pupil size, and pupil shape varies with species.

Have two layers of smooth muscle, the circular (constrict) and radial (dilate), in the middle vascular coat of the eye. Located between the cornea and lens, controls pupil size, and pupil shape varies with species.

Types of pupils

Granulae iridicae of equine pupillary margin

Horses and goats

Horizontal shaped pupils

Ciliary body

Part of the middle vascular coat with muscle bundles covered by epithelium (ciliary processes). Ciliary muscles control lens shape: contract (rounder) and relax (flattens)

Part of the middle vascular coat with muscle bundles covered by epithelium (ciliary processes). Ciliary muscles control lens shape: contract (rounder) and relax (flattens)

Parts of middle vascular coat

Choroid

Middle vascular coat that contains melanin and the tapetum lucidum

Middle vascular coat that contains melanin and the tapetum lucidum

Choroid

Tapetum lucidum

Superior to the optic disc. Not in humans or pigs.

Retina

Part of the internal coat. Contains the photoreceptors and the optic disc. Multiple layers of neutral cells (photoreceptor cells).

Part of the internal coat. Contains the photoreceptors and the optic disc. Multiple layers of neutral cells (photoreceptor cells).

Optic disc

Blind spots; where axons from the retina leave the eye. Retinal vessels enter and leave here.

Photoreceptors

Bipolar cells and ganglion cells process the information from the _______________ .

Rods

Photorecepting cell that are low, light gray. Pigmented retina

Photorecepting cell that are low, light gray.

Cones

Bright-light, color. No fovea centralis in domestic animals.

Sensory retina

Neurons

Basic function unit of the nervous system with a high requirement for oxygen. cannot reproduce but generate the cell process if the body remains intact. Have neuroglia. Has a cell body (soma or perikaryon) and dendrites (receive stimuli). Have axons and a high metabolic rate.

Axon

Conducts nerve impulses away. Single long process that may extend several feet. Some are myelinated. Have nodes of Ranvier.

Anterior chamber

Anterior portion of the chambers of the globe. Cornea to iris. 1.

Anterior portion of the chambers of the globe. Cornea to iris. 1.

Posterior chamber

Anterior portion of the chambers of the globe. Iris to lens. 2.

Anterior portion of the chambers of the globe. Iris to lens. 2.

Posterior position

Vitreous chamber (body).

Vitreous chamber (body).

Cornea, aqueous humor, lens, virtuous humor

Light strikes the eye and gets refracted by ______, ___________________, ____ , _________________.

Cornea; lens

The ______ does most of the refraction, while the ______ only fine tunes the focus.

When light converges onto the retina

Photoreceptors stimulated. Nerve signal sent to brain via optic nerve. "Image" is actually sent upside down. Occipital lobe does initial processing.