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49 Cards in this Set

  • Front
  • Back
Amoxicillin
"• Treatment of
» Skin and skin structure infections
» Otitis media
» Sinusitis
» Respiratory infections
» Genitourinary infections
• Endocarditis prophylaxis
• Postexposure inhalational anthrax prophylaxis
• Management of ulcer disease due to Helicobacter pylori
Unlabelled Use(s):
Lyme disease in children <8 yr

Side Effects
CNS: SEIZURES (HIGH DOSES) .

GI: PSEUDOMEMBRANOUS COLITIS, diarrhea, nausea, vomiting, ↑ liver enzymes.

Derm: rashes, urticaria.

Hemat: blood dyscrasias.

Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS , SERUM SICKNESS, superinfection.
"
ACETYLSALICYLIC ACID EC (Aspirin, ASA, *refer to Nursing central for more names*) - antipyretics -nonopioid analgesics
10) Analgesia, reduction of inflammation, reduction of fever, decreased incidence of transient ischemic attacks and MI, decreases platelet aggregation

Side Effects
EENT: tinnitus. GI: GI BLEEDING, dyspepsia, epigastric distress, nausea, abdominal pain, anorexia, hepatotoxicity, vomiting. Hemat: anemia, hemolysis. Derm: rash, urticaria. Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND LARYNGEAL EDEMA .
Caffeine Citrate
short-term treatment of idiopathic apnea of prematurity in infants between 28 and <33 wk gestational age

Side Effects
============
CNS: insomnia, irritability, jitteriness, restlessness.
CV: tachycardia.

GI: NECROTIZING ENTEROCOLITIS, feeding intolerance, gastritis, GI bleeding.

GU: increased urine output.

Derm: dry skin, rash, skin breakdown.

Endo: hypoglycemia, hyperglycemia.

MS: muscle tremors, twitches.
Captopril
• Alone or with other agents in the management of hypertension
• Management of heart failure
• Reduction of risk of death, heart failure-related hospitalizations, and development of overt heart failure following myocardial infarction
• Treatment of diabetic nephropathy in patients with Type 1 diabetes mellitus and retinopathy

Side Effects
CNS: dizziness, fatigue, headache, insomnia.

Resp: cough .

CV: hypotension, chest pain, palpitations, tachycardia.

GI: taste disturbances, abdominal pain, anorexia, constipation, diarrhea, nausea, vomiting.

GU: proteinuria, impaired renal function.

Derm: ANGIOEDEMA, rashes, pruritis.

F and E: hyperkalemia.

Hemat: AGRANULOCYTOSIS, neutropenia.

Misc: fever.
Cefuroxime
• Treatment of
» Respiratory tract infections
» Skin and skin structure infections
» Bone and joint infections (IV)
» Urinary tract infections
» Gynecological infections
» Septicemia (IV)
» Otitis media (PO)
» Meningitis (IV)
» Lyme disease (PO)
• Perioperative prophylaxis (IV)

Side Effects
CNS: SEIZURES (HIGH DOSES) .

GI: PSEUDOMEMBRANOUS COLITIS, diarrhea, nausea, vomiting, cramps.

Derm: rashes, urticaria, diaper dermatitis.

Hemat: bleeding, eosinophilia, hemolytic anemia, leukopenia.

Local: pain at IM site, phlebitis at IV site.

Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS , superinfection.
Clindamycin
• PO, IM, IV: Treatment of
» Skin and skin structure infections
» Respiratory tract infections
» Septicemia
» Intra-abdominal infections
» Gynecologic infections
» Osteomyelitis
» Endocarditis prophylaxis
• Topical: Severe acne
• Vag: Bacterial vaginosis
Unlabelled Use(s):
PO, IM, IV: Treatment of Pneumocystis carinii pneumonia, CNS toxoplasmosis, and babesiosis

Side Effects
CNS: dizziness, headache, vertigo.

CV: arrhythmias, hypotension.

GI: PSEUDOMEMBRANOUS COLITIS, diarrhea, bitter taste (IV only), nausea, vomiting.

Derm: rashes.

Local: phlebitis at IV site.
Clonidine
• PO, Transdermal: Management of mild to moderate hypertension
• Epidural: Management of cancer pain unresponsive to opioids alone
Unlabelled Use(s):
• Management of opioid withdrawal
• Treatment of attention-deficit hyperactivity disorder (ADHD)
• Adjunctive treatment of neuropathic pain

Side Effects

CNS: drowsiness, depression, dizziness, nervousness, nightmares.

CV: bradycardia, hypotension (↑ with epidural), palpitations.

GI: dry mouth, constipation, nausea, vomiting.

GU: erectile dysfunction.

Derm: rash, sweating.

F and E: sodium retention.

Metabolic: weight gain.

Misc: withdrawal phenomenon.
Cloxacillin
Treatment of the following infections due to penicillinase-producing staphylococci
» Respiratory tract infections
» Sinusitis
» Skin and skin structure infections

Side Effects
CNS: SEIZURES.

GI: diarrhea, epigastric distress, nausea, vomiting, pseudomembranous colitis.

GU: interstitial nephritis.

Derm: rash, urticaria.

Hemat: eosinophilia, leukopenia.

Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND SERUM SICKNESS , superinfection.
Cotrimoxazole
• Treatment of uncomplicated urinary tract infections
• Treatment of uncomplicated otitis media in children
Unlabelled Use(s):
• Prophylaxis of chronic recurrent urinary tract infections
• Treatment of head lice
• With dapsone in the management of mild to moderate Pneumocystis jirovecii pneumonia (PCP)

Side Effects
GI: altered taste, epigastric discomfort, glossitis, nausea, vomiting, drug-induced hepatitis.

Derm: pruritus, rash.

Hemat: megaloblastic anemia, neutropenia, thrombocytopenia.

Misc: fever.
Diazepam
• Adjunct in the management of
» Anxiety Disorder
» Athetosis
» Anxiety relief prior to cardioversion (injection)
» Stiffman Syndrome
» Preoperative sedation
» Conscious sedation (provides light anesthesia and anterograde amnesia)
• Treatment of status epilepticus/uncontrolled seizures (injection)
• Skeletal muscle relaxant
• Management of the symptoms of alcohol withdrawal
Unlabelled Use(s):
Anxiety associated with acute myocardial infarction, insomnia

Side Effects
CNS: dizziness, drowsiness, lethargy, depression, hangover, ataxia, slurred speech, headache, paradoxical excitation.

EENT: blurred vision.

Resp: respiratory depression.

CV: hypotension (IV only).

GI: constipation, diarrhea (may be caused by propylene glycol content in oral solution), nausea, vomiting, weight gain.

Derm: rashes.

Local: pain (IM), phlebitis (IV), venous thrombosis.

Misc: physical dependence, psychological dependence, tolerance.
Diphenhydramine
• Relief of allergic symptoms caused by histamine release including
» Anaphylaxis
» Seasonal and perennial allergic rhinitis
» Allergic dermatoses
• Parkinson's disease and dystonic reactions from medications
• Mild nighttime sedation
• Prevention of motion sickness
• Antitussive (syrup only)

Side Effects

CNS: drowsiness, dizziness, headache, paradoxical excitation (increased in children).

EENT: blurred vision, tinnitus.

CV: hypotension, palpitations.

GI: anorexia, dry mouth, constipation, nausea.

GU: dysuria, frequency, urinary retention.

Derm: photosensitivity.

Resp: chest tightness, thickened bronchial secretions, wheezing.

Local: pain at IM site.
Digoxin
• Heart failure
• Atrial fibrillation and atrial flutter (slows ventricular rate)
• Paroxysmal atrial tachycardia

SIDE EFFECTS

CNS: fatigue, headache, weakness.

EENT: blurred vision, yellow or green vision.

CV: ARRHYTHMIAS, bradycardia, ECG changes, AV block, SA block.

GI: anorexia, nausea, vomiting, diarrhea.

Hemat: thrombocytopenia.

Metabolic: electrolyte imbalances with acute digoxin toxicity.
Erythromycin
• IV, PO: Infections caused by susceptible organisms including:
» Upper and lower respiratory tract infections
» Otitis media (with sulfonamides)
» Skin and skin structure infections
» Pertussis
» Diphtheria
» Erythrasma
» Intestinal amebiasis
» Pelvic inflammatory disease
» Nongonococcal urethritis
» Syphilis
» Legionnaires' disease
» Rheumatic fever

• Useful when penicillin is the most appropriate drug but cannot be used because of hypersensitivity, including
» Streptococcal infections
» Treatment of syphilis or gonorrhea
• Topical: Treatment of acne

SIDE EFFECTS
=============
CNS: seizures (rare).

EENT: ototoxicity.

CV: QT C PROLONGATION (MAY RESULT IN TORSADES DE POINTES) , VENTRICULAR ARRHYTHMIAS, .

GI: nausea, vomiting, abdominal pain, cramping, diarrhea, drug-induced hepatitis, infantile hypertrophic pyloric stenosis, drug-induced pancreatitis (rare).

Derm: rashes.

Local: phlebitis at IV site.

Misc: allergic reactions, superinfection.
Ferrous sulphate
PO: Treatment & prevention iron deficiency anemia

SIDE EFFECTS
=============
CNS: dizziness, headache, syncope.

GI: nausea, constipation, dark stools, epigastric pain, GI bleeding, vomiting.

Misc: temporary staining of teeth (liquid preparations).
Furosemide; Lasix; loop diuretics
Loop diuretics;
• Edema due to heart failure, hepatic impairment or renal disease
• Hypertension

SIDE EFFECTS
=============
hypo- calcemia/-chloremia/-kalemia/-magesemia/-natremia/-volemia, dehydration, metabolic alkalosis. aplastic anemia, agranulocytosis
Hydroxyzine
• Treatment of anxiety
• Preoperative sedation
• Antiemetic
• Antipruritic
• May be combined with opioid analgesics

SIDE EFFECTS
==============
CNS: drowsiness, agitation, ataxia, dizziness, headache, weakness.

Resp: wheezing.

GI: dry mouth, bitter taste, constipation, nausea.

GU: urinary retention.

Derm: flushing.

Local: pain at IM site, abscesses at IM sites.

Misc: chest tightness.
Nitrofurantoin
Prevention and treatment of urinary tract infections caused by susceptible organisms; not effective in systemic bacterial infections

SIDE EFFECTS
============
CNS: dizziness, drowsiness, headache.

EENT: nystagmus.

Resp: PNEUMONITIS, PULMONARY FIBROSIS.

CV: chest pain.

GI: HEPATOTOXICITY, PSEUDOMEMBRANOUS COLITIS, anorexia, nausea, vomiting, abdominal pain, diarrhea.

GU: rust/brown discoloration of urine.

Derm: photosensitivity.

Hemat: blood dyscrasias, hemolytic anemia.

Neuro: peripheral neuropathy.

Misc: hypersensitivity reactions.
Nystatin
Treatment of a variety of cutaneous fungal infections, including cutaneous candidiasis, tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea versicolor

SIDE EFFECTS
============
Local: burning, itching, local hypersensitivity reactions, redness, stinging.
Ondansetron; Zofran; antiemetics
• Prevention of nausea and vomiting associated with chemotherapy or radiation therapy

• IM, IV: Prevention and treatment of postoperative nausea and vomiting

SIDE EFFECTS
============
CNS: headache, dizziness, drowsiness, fatigue, weakness.

GI: constipation, diarrhea, abdominal pain, dry mouth, ↑ liver enzymes.

Neuro: extrapyramidal reactions.
Phenobarbital
• Anticonvulsant in tonic-clonic (grand mal), partial, and febrile seizures in children
• Preoperative sedative and in other situations in which sedation may be required
• Hypnotic (short-term)
Unlabelled Use(s):
Prevention/treatment of hyperbilirubinemia in neonates

SIDE EFFECTS
==========
CNS: hangover, delirium, depression, drowsiness, excitation, lethargy, vertigo.

Resp: respiratory depression, IV—LARYNGOSPASM, bronchospasm.

CV: IV—hypotension.

GI: constipation, diarrhea, nausea, vomiting.

Derm: photosensitivity, rashes, urticaria.

Local: phlebitis at IV site.

MS: arthralgia, myalgia, neuralgia.

Misc: HYPERSENSITIVITY REACTIONS INCLUDING ANGIOEDEMA AND SERUM SICKNESS , physical dependence, psychological dependence.
Prednisolone
• Used systemically and locally in a wide variety of chronic diseases including
» Inflammatory
» Allergic
» Hematologic
» Neoplastic
» Autoimmune disorders
• Suitable for alternate-day dosing in the management of chronic illness
• Replacement therapy in adrenal insufficiency
Unlabelled Use(s):
• Adjunctive therapy of hypercalcemia
• Adjunctive management of nausea and vomiting from chemotherapy

SIDE EFFECTS
================
Adverse reactions/side effects are much more common with high-dose/long-term therapy

CNS: depression, euphoria, headache, ↑ intracranial pressure (children only), personality changes, psychoses, restlessness.

EENT: cataracts, ↑ intraocular pressure.

CV: hypertension.

GI: PEPTIC ULCERATION, anorexia, nausea, vomiting.

Derm: acne, ↓ wound healing, ecchymoses, fragility, hirsutism, petechiae.

Endo: adrenal suppression, hyperglycemia.

F and E: fluid retention (long-term high doses), hypokalemia, hypokalemic alkalosis.

Hemat: THROMBOEMBOLISM, thrombophlebitis.

Metabolic: weight gain, weight loss.

MS: muscle wasting, osteoporosis, avascular necrosis of joints, muscle pain.

Misc: cushingoid appearance (moon face, buffalo hump), ↑ susceptibility to infection.
Propranolol
• Management of hypertension, angina, arrhythmias, hypertrophic cardiomyopathy, thyrotoxicosis, essential tremors, pheochromocytoma
• Also used in the prevention and management of MI, and the prevention of vascular headaches
Unlabelled Use(s):
• Also used to manage alcohol withdrawal, aggressive behavior, antipsychotic-associated akathisia, situational anxiety, and esophageal varices
• Post-traumatic stress disorder (PTSD)(Ongoing clinical trials at National Institute for Mental Health [NIMH])

SIDE EFFECTS
=============
CNS: fatigue, weakness, anxiety, dizziness, drowsiness, insomnia, memory loss, mental depression, mental status changes, nervousness, nightmares.

EENT: blurred vision, dry eyes, nasal stuffiness.

Resp: bronchospasm, wheezing.

CV: ARRHYTHMIAS, BRADYCARDIA, CHF, PULMONARY EDEMA, orthostatic hypotension, peripheral vasoconstriction.

GI: constipation, diarrhea, nausea.

GU: erectile dysfunction, ↓ libido.

Derm: itching, rashes.

Endo: hyperglycemia, hypoglycemia (↑ in children).

MS: arthralgia, back pain, muscle cramps.

Neuro: paresthesia.

Misc: drug-induced lupus syndrome.
Ranitidine
• Short-term treatment of active duodenal ulcers and benign gastric ulcers
• Maintentance therapy for duodenal and gastric ulcers after healing of active ulcer(s)
• Management of gastric hypersecretory states (Zollinger-Ellison syndrome)
• Treatment of and maintenace therapy for erosive esophagitis
• Treatment of gastroesophageal reflux disease (GERD)
• Heartburn, acid indigestion, and sour stomach (OTC use)
• IV: Prevention and treatment of stress-induced upper GI bleeding in critically ill patients

SIDE EFFECTS
============
CNS: confusion, dizziness, drowsiness, hallucinations, headache.

CV: ARRHYTHMIAS.

GI: constipation, diarrhea, nausea.

GU: decreased sperm count, erectile dysfunction.

Endo: gynecomastia.

Hemat: AGRANULOCYTOSIS, APLASTIC ANEMIA, anemia, neutropenia, thrombocytopenia.

Local: pain at IM site.

Misc: hypersensivity reactions, vasculitis.
SPIRONOLACTONE (Aldactone/Novospiroton) - diuretic (potassium sparing diuretics) - Antihypertensive - Antiedemic - treat hypokalemia
13) Conservation of K+; â Edema, â bld vol therefore â HPTN.

SIDE EFFECTS
============
CNS: dizziness, clumsiness, headache.
CV: arrhythmias.
GI: GI irritation.
GU: erectile dysfunction, dysuria.
Endo: gynecomastia (in males), breast tenderness, , deepening of voice, increased hair growth (in females).
F and E: hyperkalemia, hyponatremia, hyperchloremic metabolic acidosis.
Hemat: agranulocytosis.
MS: muscle cramps.
Misc: allergic reactions.
Valproic acid
• Monotherapy and adjunctive therapy for simple and complex absence seizures
• Monotherapy and adjunctive therapy for complex partial seizures
• Adjunctive therapy for patients with multiple seizure types, including absence seizures
• Divalproex sodium only:
» Manic episodes associated with bipolar disorder
» Prevention of migraine headache

SIDE EFFECTS
==================
CNS: SUICIDAL THOUGHTS, agitation, dizziness, headache, insomnia, sedation, confusion, depression.

CV: peripheral edema.

EENT: visual disturbances.

GI: HEPATOTOXICITY, PANCREATITIS, abdominal pain, anorexia, diarrhea, indigestion, nausea, vomiting, constipation, increased appetite.

Derm: alopecia, rashes.

Endo: weight gain.

Hemat: leukopenia, thrombocytopenia.

Metabolic: HYPERAMMONEMIA.

Neuro: HYPOTHERMIA, tremor, ataxia.
ACETAMINOPHEN*
ANALGESIC

10-15 mg/kg/dose po

q4 – 6h
DO NOT EXCEED 5 DOSES PER 24 HRS
IBUPROFEN*
ANALGESIC

4-10 mg/kg/dose po q6 – 8h
(FOR> 6 Mos)
NAPROXEN
ANALGESIC

>2 yrs 5-7 mg/kg/dose po q8 – 12h
25-49 kg: 250 mg/dose pr q12h
> 50 kg: 500 mg/dose pr q12h
MORPHINE
ANALGESIC

0.2 - 0.5 mg/kg/dose po q4 – 6h
0.1 mg/kg/dose IV q 2h
(MAX DOSE IS 0.2 mg/kg PER 2 hr INTERVAL)
0.05 mg/kg/dose IV q10 min X 2 prn FOR BREAKTHROUGH PAIN
CODEINE
ANALGESIC

0.5 - 1.0 mg/kg/dose po
Max 60 mg/dose
Note: Codeine is ineffective in
approximately 1/3 of all children
q4 – 6h
OXYCODONE IR
(immediate release)
ANALGESIC

0.05 – 0.15 mg/kg/dose po q 4-6h
DIMENHYDRINATE
(Antiemetic)
12.5 – 25 mg po, IV, pr 2 – 5 YRS.

25 – 50 mg po, IV, pr 6-12 YRS.

q6-8h (max. dose is 5 mg/kg/day to
a max of 75 mg/day)

q6-8h ( max. dose is 5 mg/kg/day to a max of 150 mg/day)
MEPERIDINE
Meperidine is not recommended for use with children.
* ACETAMINOPHEN &
IBUPROFEN
Give together for better effect for pain but not for fever
Atrovent (ipratropruim bromide)
Anticholinergic
Ventolin (salbutamol)
Bronchodilator
Bricanyl (terbutaline)
Bronchodilator
Advair (flovent & salmeterol)
Combination
Symbicort (pulmicort & oxeze)
Combination
Pulmicort (budesonide)
Corticosteroid
Flovent (fluticasone)
Corticosteroid
QVAR
Corticosteroid
Pulmozyme
Dornase Alfa Recombinant
Singular (montelukast) – tablet form
Leukotriene Receptor Antagonist
Gentamicin
Respiratory Antibiotic
Tobramycin (TOBI)
Respiratory Antibiotic
Flonase
Nasal Steroid Spray
Nasonex
Nasal Steroid Spray
Nasocort
Nasal Steroid Spray