Neprhitic/ Nephrotic Syndromes

Front 1

hematuria, RBC casts, azotemia, oliguria and HTN

Back 1

nephritic syndrome

Front 2

lumpy bumpy

Back 2

acute post strep GN

Front 3

Em: sub-epi immune complex humps

Back 3

acute post strep GN

Front 4

granular appearance due to IgG, IgM and C3 deposits along GBM and mesangium

Back 4

acute post strep GN

Front 5

peripheral and periorbital edema, dark urine, resolves spontaneously

Back 5

acute post strep GN

Front 6

cresent moon shape

Back 6

rapidly progressive glomerulonephritis (RPGN)

Front 7

pressence of fibrin, plasma protein (C3b) with glomerular parietal cells, monocytes and macrophages

Back 7

rapidly progressive glomerulonephritis (RPGN)

Front 8

what 3 diseases will progress to rapidly progressive glomerulonephritis (RPGN)

Back 8

good pastures
wegeners granulomatosis (cANCA)
microscopic polyangitis (pANCA)

Front 9

hemoptysis annd blood in the urine

Back 9

goodpastures

can lead to rapidly progressive glomerulonephritis (RPGN)

Front 10

due to SLE or MPGN

Back 10

diffuse proliferative GN

Front 11

wire looping

Back 11

diffuse proliferative GN

(seen with lupus)

Front 12

most common cause of death for SLE patients

Back 12

diffuse proliferative GN

Front 13

EM: subendothelial and intramembranous IgG based ICD and C3 deposition

Back 13

diffuse proliferative GN

Front 14

LM: mesangial proliferation
EM: mesangial ICD
IF: IgA based ICD deposits in the mesangium

Back 14

IgA nephropathy

Front 15

Ppx with palapable purpura on trunk and lower extremities and complains of abdominal pain and bloody urine... most likey ddx?

Back 15

IgA nephropathy

Front 16

type 4 collagen mutation leaing to split basement membrane

Back 16

alports syndrome

Front 17

eyes, ears and kidneys affected

Back 17

alports syndrome

nerve disorder, ocular disorders, deafness and GN

Front 18

genetics of alport's syndrome?

Back 18

XLR

Front 19

hyperlipidemia, thromboembolism, edema, fatty casts, increased risk of infection

Back 19

nephrotic syndrome

Front 20

HIV

Back 20

FSGS

Front 21

segmental sclerosis and hyalinosis on LM

Back 21

FSGS

Front 22

LM: diffuse capillary and GBM thickening
EM: spike and Dome with sub-epi deposits
IF granular

Back 22

membranous glomerulonephritis/ -opathy

(still a nephrotic syndrome)

Front 23

MC cause of adult nephrotic syndrome

Back 23

FSGS

Front 24

podocyte effacement

Back 24

FSGS or MCD

Front 25

MC cause of GN in kids

Back 25

MCD

Front 26

selective loss of albumin (not globulins)

Back 26

MCD

Front 27

LM shows congo-red, apple green birefringence

Back 27

amyloidosis

associated with MM, TB and RA

Front 28

subendothelial ICD with granular immunofluorescence

Back 28

Membranoproliferative GN

Front 29

tram track appearance due to GMD splitting cuased by mesangial ingrowth

Back 29

Type I

membranoproliferative GN

Front 30

dense seposits

Back 30

Type II

membranoproliferative GN

Front 31

associated with HBV

Back 31

Type I

membranoproliferative GN

Front 32

associated with C3 neprhitic factor

Back 32

type II

membranoproliferative GN

Front 33

kimmelstein wilson nodules

Back 33

Diabetic GN

Front 34

NEG of GBM that leads to increase permiability and thickening

Back 34

Diabetic GN

Front 35

LM: mesangial expansion, GBM thickening, eosinophilic nodular glomerulosclerosis

Back 35

(description for KWN)

Diabetic GN