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6 Cards in this Set
- Front
- Back
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Membranous glomerulonephritis- most common adult nephrotic
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LM: capillary/BM thickening
EM: subepithelial "spike and dome" IF: granular Immune complexes Systemic disease, drugs, infection |
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Minimal Change Disease
- childhood, responds to steroids |
LM: normal glomeruli
EM: foot process effacement Selective proteinuria- only albumin lost |
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Focal Segmental Glomerular Sclerosis- HIV
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LM: Segmental sclerosis
IF: IgG, C3 |
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Diabetic Nephropathy
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Kimmelstiel-Wilson nodules
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SLE- anti-phospholipid Ab
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Class IV: Diffuse proliferative- "wire loop"- subendothelial, mesangial, capillary loops, immune complexes
Class V: Membranous glomerulonephritis- subepithelial deposits |
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Amyloidosis- associated with MM, TB, RA
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IF: Congo red, apple-green birefringence
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