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13 Cards in this Set
- Front
- Back
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What is the definitive test to Dx Turner's?
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Karyotype: 45,X
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What are the characteristics of Turners?
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Estrogen def.
No avaries Increased levels of LH/FSH Short with Webbed neck Low set ears Coarctation of the aorta |
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How do you treat Turners?
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Growth hormone-helps with stature
Estrogen replacement- for 2dary sex characteristics Removal of streak ovaries-they >risk of CA |
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How do people with Testicular Feminization Syndrome look like?
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All male with external female genitalia
No fallopian tubes, uterus, or upper vagina |
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How do you treat TFS?
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Removal of testes
Life time estrogen therapy |
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Name the causes of primary amenorrhea
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Turner’s Syndrome
TFS Panhypopituitarism Hypogonadotropic hypogonadism Resistant ovary syndrome Delayed menarche Isolated gonadism deficiency |
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When is polycystic ovary syndrome most common?
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Post purberty
Between 20-30 y/o |
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What are the clinical features of POS?
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Hirtuism
Obesity Oligomenorrhea Infertility |
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How do you DX POS?
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Serum LH- will be low
Ultrasound- presence of cysts on ovaries |
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What are the characteristics of Isolated gonadotrophic deficiency?
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Low LH/FSH
Anosmia |
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Name 3 conditions that cause testicular failure
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Viral infection(mumps)
Irradiation Cancer chemotherapy |
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What are the manifestations of androgen deficiency?
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Hypospadias
Cryptochidism Microphallus Decreased libido Sexual dysfunction |
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How do you Dx androgen deficiency?
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Pituitary function test
Testosterone, LH/FSH levels Pituitary CT/MRI |
