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13 Cards in this Set

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What is the definitive test to Dx Turner's?
Karyotype: 45,X
What are the characteristics of Turners?
Estrogen def.
No avaries
Increased levels of LH/FSH
Short with Webbed neck
Low set ears
Coarctation of the aorta
How do you treat Turners?
Growth hormone-helps with stature
Estrogen replacement- for 2dary sex characteristics
Removal of streak ovaries-they >risk of CA
How do people with Testicular Feminization Syndrome look like?
All male with external female genitalia
No fallopian tubes, uterus, or upper vagina
How do you treat TFS?
Removal of testes
Life time estrogen therapy
Name the causes of primary amenorrhea
Turner’s Syndrome
TFS
Panhypopituitarism
Hypogonadotropic hypogonadism
Resistant ovary syndrome
Delayed menarche
Isolated gonadism deficiency
When is polycystic ovary syndrome most common?
Post purberty
Between 20-30 y/o
What are the clinical features of POS?
Hirtuism
Obesity
Oligomenorrhea
Infertility
How do you DX POS?
Serum LH- will be low
Ultrasound- presence of cysts on ovaries
What are the characteristics of Isolated gonadotrophic deficiency?
Low LH/FSH
Anosmia
Name 3 conditions that cause testicular failure
Viral infection(mumps)
Irradiation
Cancer chemotherapy
What are the manifestations of androgen deficiency?
Hypospadias
Cryptochidism
Microphallus
Decreased libido
Sexual dysfunction
How do you Dx androgen deficiency?
Pituitary function test
Testosterone, LH/FSH levels
Pituitary CT/MRI