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15 Cards in this Set
- Front
- Back
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Nephritic Syndrome
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Inflamatory process
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Clinical presentation
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hematuria
RBC casts in urine azotemia oliguria HTN proteinuria (<3.5 g/day) |
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LM of Acute poststreptococcal glomerulonephritis
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Glomeruli enlarged and hypercellular
neutrophils LUMPY-BUMPY apperance |
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EM of Acute poststreptococcal glomerulonepritis
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Subepithelial immune complex humps
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LM + IF of RPGN
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Crescent moon shaped
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Diseases w crescent pattern (3)
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1- Goodpasture= antibodies against GBM
2- Wegener= c-ANCA 3- Micoscopic polyarteritis= p-ANCA |
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Diffuse prolifferative nephritis can be due to
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SLE- most common cause of death
MPGN |
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what is Diffuse prolifferative nephritis
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subendothelial DNA anti- DNA ICs
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What u can observed in Diffuse prolifferative nephritis ?
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wire looping of capillaries
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Berger's Disease
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↑synthesis of IgA
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LM & IF of Berger's Disease
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ICs deposist in mesangium
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How Berger's Disease presents?
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URI or acute gastroenteritis
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what is the mutation in Alport's syndrome?
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collagen type IV
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How Alport's syndrome is presents?
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nerve disorders
ocular disorders deafness |
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IF of Goodpasture's
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Linear pattern
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