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17 Cards in this Set
- Front
- Back
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What is the agent that causes neosporosis?
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Neospora caninum
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What is the definitive host of Neospora caninum?
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Dogs
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What is the distribution of Neospora caninum?
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Enzootic worldwide
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Neosporosis is most common in _____ and _____ .
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Cattle & dogs
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What are the 3 routes of Neospora transmission?
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1) Ingestion of cysts in infected animal tissues
-**Important in dogs 2) Ingestion of oocysts shed in dog feces 3) Congenital (transplacental) |
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The clinical signs of neosporosis are similar to _______.
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Toxoplasmosis
-think toxo in dogs |
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What are the predominate clinical signs of neosporosis?
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Neurologic and muscular abnormalities
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What are 5 clinical signs of neosporosis in young dogs (<6 months)?
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1) Ascending paralysis
2) Gradual muscle atrophy 3) Stiffness of pelvic limbs 4) Dysphagia 5) Ataxia |
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What are the 3 clinical signs of neosporosis in old dogs?
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1) CNS signs
-seizures & tremors 2) Polymyositis 3) Myocarditis |
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What are the lab abnormalities seen on a chemistry profile of an animal with neosporosis?
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Increased CK and AST if there's muscle involvement
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What lab abnormalities are found in the CSF of an animal with neosporosis?
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Slight increase in protein and cell count (mostly small mononuclear cells)
-most protozoal and viral diseases don't cause change in CSF |
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Is demonstration of the organism very common in CSF or tissue samples of an animal with Neosporosis?
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No, very rare (can be mistaken for toxoplasmosis)
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What do you look on serology when trying to diagnose neosporosis? Is there any cross reactivity with toxoplasmosis?
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IgG titer > 1:200
-minimal cross reactivity with T. gondii |
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When will IgG titers be high in the CSF of an animal with neosporosis?
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Titers may be high in cases with CNS signs
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What are the 2 components of treating animals with neosporosis?
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1) Supportive therapy
2) Antimicrobials -Clindamycin -Sulfonamide + trimethoprin + pyrimethamine *pretty much same as toxo |
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What are 2 ways to prevent neosporosis?
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1) Bitches that whelped affected puppies should not be bred
2) Avoid glucocorticoids in seropositive dogs |
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How does the treatment for neosporosis vary from the treatment for toxoplasmosis?
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Topical corticosteroids are not recommended for neosporosis but it is recommended for toxoplasmosis
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