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12 Cards in this Set
- Front
- Back
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What are the two overarching categories of preinvasive neoplastic vulvar cancers?
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-squamous (intraepithelial neoplasia)
-nonsquamous (melanoma, paget's dz) |
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Define: Vulvar Intraepithelial Neoplasia
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Cellular atypia contained within the epithelium of the vulva
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Vulvar pruritis that does not respond to antifungal cream should alert the doctor to look for what?
-antifungals? -what to look for? -what other sx might you expect to find? |
If it doesn't respond to fungal cream, it's probably not candidiasis, which is what the initial hypothesis was/is with vulvar pruritis
The pruritis, along with a palpable abnormality and perineal burning may be suggestive of VIN and warrants a biopsy |
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Treatment for VIN?
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-local incision
-laser vaporization |
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You read a phsyicians note detailing: "hyperemic, sharply demarcated, theickened areas of excoration and induration on patient's vulva. pt complains of pruritis and has velvety red lesions of the skin that scar into white plaques."
what is being described? |
Paget's disease of the vulva
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Most common type of vulvar cancer?
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Squamous cell carcinoma (90%)
-others: malignant melanoma, basal cell carcinoma, |
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most important prognostic factor for vulvar cancer?
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number of positive inguinal lymph nodes it spreads to
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Define: VAIN
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Vaginal intraepithelial neoplasia. premalignant lesion similar to vulva and cervix. by definition its squamous cell atypia limited to the epithelium
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CIN, VIN, VAIN --> which is the least common?
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VAIN
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DES exposure in utero is associated with what type of vaginal cancer?
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clear cell adenocarcinoma of the vagina
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Describe the treament options for vulvar cancer
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radical local incision -- Stage I
radical vulvectomy -- Stages II, III, IV (a radical vulvectomy is the removal of all external genitalia, clitorus, lymph nodes, and surrounding tissue) |
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Topical 5-FU is used to treat VIN or VAIN?
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VAIN
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