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10 Cards in this Set
- Front
- Back
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What is cancer cachexia and causes?
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-loss of body fat, wasting, and profound weakness
-loss of appetite (anorexia), metabolic changes, TNF-a |
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what are para-neoplastic syndromes?
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distant effects of a tumor unrelated to primary tumor or metastasis
(can represent earliest manifestation of a cancer) -occurs in 10-15% of cancer pts |
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Small cell carcinoma
-give 2 clinical syndromes that can be due to? |
1= cushing syndrome (diabetes, weight loss, HTN)- ATCH or ATCH like substance
2=SIADH-ADH |
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Renal cell carcinoma
clinical syndrome? mechanism? |
-hypercalcemia
-PTH-related protein (PTHRP) |
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Renal cell carcinoma
clinical syndrome? mechanism? |
-polycythemia
-erythropoietin |
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Visceral malignancy- gastric CA
clinical syndrome? mechanism? |
-acanthosis nigricans
-immunological EGF secretion |
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Bronchogenic CA
clinical syndrome? mechanism? |
-hypertrophic osteoarthropathy (clubbing)
-periosteal rxn of distal phalynx |
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Pancreatic CA
clinical syndrome? mechanism? |
-superficial migratory thrombo-phlebitis (Trousseau phenomenon)
-tumor products that activate clotting |
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Advanced cancers
clinical syndrome? mechanism? |
-non-bacterial thrombotic endocarditis
-hyper-coagulability |
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medullary carcinoma of thyroid
clinical syndrome? mechanism? |
-hypocalcemia
-calcitonin |
