Neoplasia

Front 1

What contributes to neoplasia formation?

Back 1

-genes
-environment
-viruses
-skewed molecular signals
-cells not allowed apoptosis
-hormones

Front 2

Which type of cells in our body divide most often?

Back 2

epithelial tissue

Front 3

parenchymal cell

Back 3

primary neoplastic cells that have undergone transformation

Front 4

stromal vells

Back 4

supporting cells that conist of conneective tissue, blood vessels, etc (they support parenchymal cell life)

Front 5

benign

Back 5

-usually named with "-oma", also polyp and cyst
-well differntiated
-cells look like normal cells
-slow growth
-MAY cease growth for awhile
-usually progress at some point
-encapsulated
-does not incade neighboring tissues

Front 6

malignant

Back 6

-not well differntiated/are atypical
-do not look like normal origination cells
-erratic growth rate which may be rapid or slow
-locally invasive (send projections into neighboring tissues)

Front 7

anaplastic

Back 7

malignant, unrecognizable cell

Front 8

carcinoma

Back 8

any malignant neoplasia arising from dissues derived from embryonic mesoderm
-bones, muscle, blood vessels

Front 9

------ adenocarcinoma

Back 9

any malignant neoplastic process occurring in epithelial tissues that arises from GLANDS
-mammary adenocarcinoma
-salivary adenocarcinoma
-pancreatic adenocarcinoma

Front 10

Non-benign "oma's"

Back 10

mesothelioma - malignant process of mesothelium
lymphoma - malignant process of lymphatic system
melanoma - malignant process of melanocytes

Front 11

dysplasia

Back 11

dosrderly but non-neoplastic proliferation
-usually in epithelial tissues
-may develop into neoplasia
-if it effects the entire epithelium layer, it is termed "cvarcinoma in situ"

Front 12

metaplasia

Back 12

reversible change where one cell type is replaced by another cell type
-a protective mechanism agains chronic insult or stress

Front 13

paraneoplastic syndrome

Back 13

when a neoplasm emits a substance that results in effect that is not directly related to growth, invasion, or metastasis of itself
-eg. hormone like substances

Front 14

Diagnostic methods for Neoplasia

Back 14

-history and physical exam (weightloss, fatigue, pain, palpable mass)
-radiographs (x-ray, CT, US)
-lab analyses (anemia, enzyme abnormalities, hematiuria)
-cytology
-biopsy and surgery
-autopsy

Front 15

Does dysplasia mean pre cancerous?

Back 15

false - no

Front 16

Can malignant cells be well differentiated?

Back 16

No - false

Front 17

Two ways malignant cells differ from normal cells

Back 17

-lose contact inhibition
-can divide unanchored

Front 18

In the last half of 20th century, the # of ____ cancer deaths increased markedly.

Back 18

lung

Front 19

chimney sweeps often got what form of cancer

Back 19

squamous cell carcinoma of scrotum

Front 20

# of cancer survivors in 2001

Back 20

100 million

Front 21

3 ways benign tumor could cause pathological problems

Back 21

1) Location and impingement on adjacent structures.
2) Bleeding and infections when the tumor ulcerates through adjacent surfaces.
3) Symptoms that result from rupture or infarction.