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10 Cards in this Set

  • Front
  • Back

Neonatal bleeding management

1. Stop active bleeding


2. Treat shock as an emergency


3. Secure umbilical catheterization


4. Normal saline 10ml/kg/bolus over 20 minutes


5. Whole blood 20ml/kg IV over 3-4 hours to correct anemia and hypovolemic shock


6. Fresh frozen plasma 10ml/kg 3-4 hours to correct bleeding and hypovolemia


7. Vitamin K 5mg IM or IV stat


8. Platelet concentrate 1U IV slowly in case of thrombocytopenia

Neonatal hypoglycemia management

1. Identify cause


2. Breast milk or formula milk oral feeding every 2 hours for asymptomatic neonates


3. 10% DW 2ml/kg IV


4. Maintain glucose supply 6-8mg/kg/min


5. Increase concentration to 12mg/kg/min if no improvement in plasma glucose level


6. Start hydrocortisone or glucagon in persistent and resistant hypoglycemia

Neonatal hypothermia management

1. Active warming (internal warming):


- Warm IV fluids


- Warm humidified oxygen



2. Passive (external warming):


- Adequate body clothing


- Radiant heater or incubator; heater blanket


- Correct hypotension using normal saline


- Treat concomitant sepsis and hypoglycemia


- Keep under thermo-neutral environment

Exchange transfusion in neonatal jaundice

- Most important and effective method


- Umbilical vein catheterization


- Double volume blood exchange (2 X 80ml/kg)


- The procedure washes 87% of the total blood


- Reduces jaundice by 40-60% of pre-exchange level


- It removes bilirubin, hemolyzed blood, Igs, and bacteria



Complications:


- Volume overload


- Electrolytes imbalance


- Acid base disorder


- Blood clotting, embolization, and infections

Phototherapy in neonatal jaundice

*Bilirubin absorbs light in blue range wavelength (425-475nm)


- Structural isomerization (cyclization) to Limirubin. Fast reaction and irreversibility so most important method


- Photo-isomerization from 4Z, 15Z to 4Z, 15E but it is reversible back to its original isoform


- Photo-oxidation: least important as it is a slow process



Complications:


- Insensible water loss


- Loose stools


- Eye injury


- Bronze baby syndrome

Neonatal sepsis management

1. Admit pt to NICU


2. Keep maintenance fluid 10% DW on 1st day then to 10% DW and 1/3rd NS from next day onwards


3. Amoxicillin 200mg/kg/day in two divided doses


4. Gentamicin 3.5mg/kg/day IV


5. Oxygen support; correct hypoglycemia


6. Keep under radiant heater or incubator


7. Feeding of breast milk via NG tube or cup feeding


8. Fresh frozen plasma for DIC or shock

Neonatal Tetanus management

1. Control spasms: Diazepam, silent room


2. Control toxin: TAT, human antitoxin


3. Eradicate C. tetani: Metronidazole or Crystalline penicillin


4. Wound care: debridement and cleaning


5. Supportive care: oxygen, IV fluids, NGT feeding, correct electrolytes


6. Tracheostomy: for airway obstruction

Management of prematurity

1. Temperature regulation: Incubator, KMC, radiant heater


2. Maintenance fluid: Slowly increase from 60 to 150ml/kg/day


3. Feeding:


- Tophic feeding (small amounts to prime GIT)


- Gavage feeding: NGT (use breast milk)


- Expressed breast milk cup feeding


4. Treat sepsis: Ampicillin + Gentamicin


5. Treat accompanying complications

Complications of prematurity

1. CNS: perinatal asphyxia, apnea, intracranial bleeding, cerebral palsy, mental retardation


2. Hematology: anemia, polycythemia, bleeding, jaundice


3. GIT: NEC, feeding difficulty


4. Renal: Edema, electrolyte imbalance


5. Respiratory: RDS, congenital pneumonia, apnea


6. Immunology: Deficiency of WBC and Ig and C level


7. Metabolic: Hypoglycemia, hypothermia


8. CVS: Hypotension, PDA

TORCH infection Rx

- Syphilis: Penicillin. Mother and her partner should also be treated


- Toxoplasmosis: Spiramycin for the mother; Pyrimethamine/Sulfadoxine for the baby


- CMV, HSV, HZV: Acyclovir or Ganciclovir


- Mgt of complications like hydrocephalus, CHD, cataract, etc.. require surgical intervention