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34 Cards in this Set

  • Front
  • Back
Differential for Neck Masses
congenital
Infection or inflammatory
neoplastic
History: Age
people under 40 - masses are typically infection or congenital
risk of malignancy increases with age
patients over 40, assume mass is malignant until proven otherwise
History: Mass Growth History
if its been there for months, with no change - benign
If it is rapidly expanding - infections or could be lymphoma

if the mass flucuates over time, and increases when the patient is sick with a URI, could just be a congenital cyst
History: Symptoms
Pain related to growth and expansion
Voice changes, hoarsness, dysphagia, otalgia may indicate cervical lymph node involvement from metastasis

fever, night sweats, weight loss - think LYMPHOMA
spiking fever - acute infection
History: Social history
tobacco/alcohol/drug use
HIV status
occupational history
animal exposure
travel history
Physical Exam
do entire body workup, not just head and neck

enlargement of both left and right supraclavicular nodes may reflect thorax disease
left supraclavicular node alone may represent abdominal disease (Virchow's node)
Lymph node location and drainage
occipital - posterior scalp
postauricular - side scalp
preauricular - ear, midface nose, and front scalp, conjuctiva
Parotid - forhead middle ear, gums, parotid gland
submandibular - cheek, lips, tongue, buccal mucosa
submental - lower lip, floor of mouth, tongue
Superficial cervical - skin, lower larynx
Deep cervical - tonsils, adenoid, thyroid, esophagus, sinuses
Mass localization
Preauricular and Jaw angle - consider facial nerve function

Central Neck - thyroid, or malignant tissue, or cyst

anterior SCM - potential malignancy, congenital in children

posterior SCM - high incidence of malignancy, especially on the right side
Characteristics of the Mass
Reactive LN - mobile and firm, but not ROCK HARD, slightly tender

Rock Hard - non tender, are generally metastatic disease, and tend to be matted to underlying structures

infected nodes - isolated, asymmetric, tender, warm, and erythematous

soft - mobile masses are often cystic

rapidly expanding - lymphoma

FIrm lateral masses that move left to right but not up and down, are involved in the carotid sheath (carotid body tumor or vagal schwannoma)

immotile midline mass, that elevates with swallowing indicates a thyroid source
Diagnostics
mass persistent past 3 weeks, labs and xrays should be considered

Labs:
CBC
ESR and CRP for systemic inflammation or infection
blood culture if associated with fever
EBV or CMV serology
Bartonella Henselae (cat scratch disease) serology
Imaging Neck Masses
CT scan - first choice
MRI - if there is soft tissue or neuronal involvement
ultrasound
Fine Needle Aspiration
(do if imaging is nondiagnostic)
23-25 gauge needle

if its:
bloody - vascular
dark brown - thyroid cancer
thick and yellow - mucocele
turbid and yellow - branchial cleft cyst
purulent - abscess
Referral
To ENT or surgeon depending on presentation
DDx
Congenital
may present at any age
most common in children

branchial cysts (first - third)
due to failed obliteration of cervical sinus
can cause recurrent infections or fistula to surface (depeding on fistual or not, determines age of presentation)
treat by resecting
1st Branchial Cleft Cyst
less than 1% of cleft abnormalities
on face around ear

type 1 - duplication of auditory canal, ectodermal origin. Passes through parotid and around facial nerve. presents with fistula

type 2 - more common than type 1, below mandible, has ectoderm and mesoderm.
2nd Branchial Cleft Cyst
most common
between jaw and SCM
sinus travels toward tonsils
3rd Branchial Cleft Cyst
lower neck
anterior to SCM
ends around pharynx or thyroidn membrane
THyroglossal Duct Cyst
can be asymptomatic
become infected with URI's
can even present after the age of 20
Sistrunk operation
may contain thyroid carcinoma so inspect
Hemangioma
Most common
see in infants
compressible red or blue soft mass
Bruit on exam
likely to have hemangiomas elsewhere
observe, but if you must intervene, use glucocorticoid and laser excision
Vascular malformations
lymphatics common
soft and compressible
can be transluminated
excise, sclerotherapy, or laser
laryngocele
herniation of the saccule of the larynx
presentation with hoarseness, cough, and foreign body sensation
ranula
Mucocele on floor of mouth
painless and slow growing
located in submentum
Teratoma
Arise from pluripotential cells and contain all three germ layers

large and encapsulated, with a cystic component
Dermatoid cyst
entrapment of epithelium
post trauma
can be congenital (in the midline)
Thymic Cyst
midline cyst,
Reactive Viral Lymphadenopathy
MCC lymphadenopathy
seen in children
usually resolved within a week of resolution of viral infection
fixed firm lymph nodes may need refferal and biopsy

Mononucleosis induced lymphadenopathy in posterior triangle accompanied by axillary and inguinal lymphadenopathy
tonsillar hypertrophy
Bacterial Lymphadenopathy
suppurative lymphadenopathy from skin or throat infection
staph aureus and group A Strep
MRSA should also be considered in hospitalized patients
may needle aspiration or drainage with culture
Toxoplasmosis
inadequately cooked meat or cat feces
prolonged course of fever, malaise, myalgias, sore throat, cervical lymphadenopathy
Francisella tularensis
transmission from rabbits, ticks, or water
tonsilitis, pharyngitis, and painful lymphadenopathy
fever, chills headache, fatigue
Brucellosis
Malta fever
acquired from farm animals, butter, or milk
generalized weakness, sweating chills, malaise, headache, backache, and arthralgia
afternonn fever
Rochalimaea
exposure to cats
lymphadenopathy, fever, malaise
self limiting
requires only supportive treatment
treat with azithromycin
actinomycosis
submandibular region
painless mass
associated with dental procedures
must biopsy to diagnose
penicillin is first line treatment
Mycobacterium tuberculosis
diffuse and bilateral lymphadenopathy
atypical mycobacteria is more common among pediatric population
unilateral mass in the parotid
overlying skin becomes purple
HIV associated lymphadenopathy
idiopathic hyperplasia

think atypicals
mycobacterium tuberculosis
pneumocystis carinii, lymphoma, and Kaposi sarcoma