Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Aspirin
|
[low]COX1, [high]1&2, Analgesic, antipyretic, anti-inflam, Irre COX1(10days), GI, Urate, Reyes in Kids, Salicylate only reversable
|
|
|
Indomethacin
|
Acute gout attack, more severe CNS & CV effects
|
|
|
Ibuprofen
|
Acute gout attack, more kidney toxicity, Short T1/2, antagonize aspirin-induced platelet inhibition
|
|
|
Naproxen
|
dysmenorrhea, Medium T ½
|
|
|
Sulindac
|
Acts though a sulfide, the active metabolite, sulfide converted back to parent drug
|
|
|
Piroxicam
|
NOT for elderly patients: HIGHER incidence of bleeding, Long half life
|
|
|
Celecoxib
|
Selective COX-2 Inhibitor, Less GI, increases Mis,
|
|
|
Acetaminophen
|
NOT an NSAID, analgesic, No anti-inflam, OK w/ peptic ulcer, gout, hemophilia, [high] CYP2D Meta to liver tox via GSH Depleation, t1/2=3hr,
|
|
|
Misoprostol
|
GI protective, Synthetic PGE1 derivative (omiprizole better)
|
