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6 Cards in this Set
- Front
- Back
Propofol infusion and nutrition |
propofol infusions deliver a significant amount of calories (1.1 cal/mL) entirely consistent of omega 6 fatty acids |
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lab to follow when patient is on propofol |
serum triglyceride every 3 days |
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pathophysiology of metabolic response to injury |
injury - stimulates hypothalamus - triggers hormonal response - release CRF - stimulates ant pituitary and sympathetic pathways - inc catecholamines, inc ACTH - inc oxygen consumption, protein turnover, lipolysis - more severe organ dysfunction, infectious complications, inc mortality |
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measuring nutritional response |
(in descending order) serum transthyretin, nitrogen balance, retinol bindingprotein, total serum protein, body weight, transferrin, lymphocytes count, serum albumin level
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nutrition and TBI |
any nutrition within first 5d after TBI associated with reduced mortality rate |
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FOOD trial |
feed or ordinary diet trial conducted in UK - 3 arms: early vs delayed, NGT vs PEG, routine oral supplementation vs standard practice - early feeding demonstrated minimal, nonsignificant reduction in risk of death with early tube feeding; PEG feeding associated with inc risk of death or poor outcome of 7.8%; neither death nor poor outcome impacted by protein supplementation |