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6 Cards in this Set

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Propofol infusion and nutrition

propofol infusions deliver a significant amount of calories (1.1 cal/mL) entirely consistent of omega 6 fatty acids

lab to follow when patient is on propofol

serum triglyceride every 3 days

pathophysiology of metabolic response to injury

injury - stimulates hypothalamus - triggers hormonal response - release CRF - stimulates ant pituitary and sympathetic pathways - inc catecholamines, inc ACTH - inc oxygen consumption, protein turnover, lipolysis - more severe organ dysfunction, infectious complications, inc mortality

measuring nutritional response

(in descending order) serum transthyretin, nitrogen balance, retinol bindingprotein, total serum protein, body weight, transferrin, lymphocytes count, serum albumin level


nutrition and TBI

any nutrition within first 5d after TBI associated with reduced mortality rate

FOOD trial

feed or ordinary diet trial conducted in UK - 3 arms: early vs delayed, NGT vs PEG, routine oral supplementation vs standard practice - early feeding demonstrated minimal, nonsignificant reduction in risk of death with early tube feeding; PEG feeding associated with inc risk of death or poor outcome of 7.8%; neither death nor poor outcome impacted by protein supplementation