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30 Cards in this Set
- Front
- Back
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What does the bone marrow produce?
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RBC, WBC, platelets
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Where does blood production in the marrow occur in adults?
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Ends of the long bones
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What are the 3 proteins found in blood plasma?
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albumin, globulin and fibrinogen
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What does albumin prevent?
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Plasma from leaking into the tissues
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What happens when development of fibronogen is altered?
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Alters coagulation
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Why is the shape of the RBC important?
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Allows cells to fold over itself to get through narrow capillaries
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What regulates the production of RBC's?
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Erythropoietin
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What are platelets composed of?
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Cell fragments that are disc shaped
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What is the purpose of the lymph nodes?
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Clean and filter liquids
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What happens to the lymphatic system when the body has edema?
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Lymph pulls the fluid from the extravascular space into circulation so that it can be exccreted.
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What is hematopoiesis?
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Formation of blood
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What is hemolysis?
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Splitting ('lysis') of blood
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Where does hemolysis occur?
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Liver, blood, spleen
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What occurs in the mononuclear phagocyte system?
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macrophages circulate in tbe blood and hemolyze damaged or old cells
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What two substances do we get when hemoglobin splits?
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Iron substance
Bilirubin |
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When cells hemolyze in excess, what condition may appear related to the liver?
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Jaundice--bilirubin broken out of hemoglobin goes into circulation
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Where are Kupffer's cells located?
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Liver and spleen
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What is the first product of bone marrow?
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Stem cells
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Once a stem cell is created, what happens?
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It becomes a committed cell
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What is the average life span of a RBC?
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120 days
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A heme part of each hemoglobin needs a molecule of: __________________
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Iron
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Once heme is bound to another molecule, how many oxygen molecules can it carry?
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4 molecules of oxygen
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What does the globin portion of hemoglobin carry?
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Carbon dioxide
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Where is erythropoietin produced?
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Kidneys
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What triggers erythropoietin production?
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hypoxia--less than normal tissue oxygenation
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What do platelets do?
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Stick to injured BV walls and form platelet plugs to stop bloodflow
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What controls the growth of platelets?
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Thrombopoietin
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What is the normal life span of a platelet?
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1-2 weeks
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What is the most prominent deficiency in the blood in relation to splenectomy?
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Decreased immunity
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What organ produces most of the blood clotting factors?
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Liver
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