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68 Cards in this Set

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Med: Inject into catheter to clear occlusion (dissolve clot)
Urokinase (Abbokinase)
Vasoconstrictor to increase blood pressure and CO.
Give for cardiac arrest, hypoT
*monitor urinary output
*infuse w/ dextrose solution (not NS)
Norepinephrine (Levophed)
Low-dose: dilates renal & coronary arteries
High-dose: vasoC; increases myocardial O2 consumption
*HA is early symptom of excess
*use infusion pump
Dopamine (intropin)
Give for anaphylaxis, cardiac arrest, syncope, excessive uterine contraction
*carefully aspirate syringe before IM and SC doses
*always check strength: 1:100 for inhalation, 1:1,000 for SC or IM
*ensure adequate hydration
Epinephrine (Adrenalin)
Used for heart block, ventricular arrhythmias, and bradyC
BronchoD used for asthma and bronchospasms
*Don't give at hs (interrupts sleep patterns)
Isoproterenol (Isuprel)
Dilates cardiac veins and arteries
Decreases preload and afterload
Increases myocardial perfusion
*SE: HypoT
Sodium nitroprusside (Nitropress)
In general, nursing considerations for meds to treat hypovolemic shock, cardiac arrest, and anaphylaxis
Monitor VS
Measure urine output
Assess for extravasation
Observe extremities for color and perfusion

SE: serious rebound effect may occur
"pams" and "lams" are frequently what kind of drug?
Benzodiazepine Derivatives (Anti-anxiety) (example: DiazePAM)
General SE of Anti-anxiety drugs
Sedation
Depression, donfusion
Anger, hostility
HA
Dry mouth, constipation
BradyC
Elevations in LDH, AST, ALT
Urinary retention
General NC for Anti-anxiety drugs
Monitor liver function
Monitor for therapeutic blood levels
Avoid alcohol
Caution when performing tasks requiring alertness (driving car)
Benzos are also used as muscle relaxants, sedative, hypnotics, anticonvulsants
Use: anxiety, sedation, alcohol withdrawal, seizures
*watch for toxic buildup in elderly
*potential for abuse/addiction
*can develop tolerance
*alcohol increases CNS depression
*cigarette smoking increases clearance of drug
Diazepam (Valium)
Chlordiazepoxide (Librium)
CNS depressant for Anxiety
*safer for elderly
*No alcohol/other CNS depressants
*check renal and hepatic fnct
*don't discontinue abruptly
*addictive potential
*Safety: Orthostatic HypoT
Alprazolam (Xanax)
Clonazepam (Klonopin)
Lorazepam (Ativan)
Oxazepam (Serax)
CNS depressant used for preop sedation, conscious sedation and dx tests
Midazalam (Versed)
Anti-anxiety med
* requires >3wks to be effective
*can't give PRN
*Good for GAD (generalized anxiety disorder)
*NO ABUSE POTENTIAL - use for pts w/ previous addiction
*No ETOH or grapefruit juice
Buspirone (BuSpar)
Anti-anxiety med
*No dependence, tolerance or intoxication
*can be used for anxiety relief for indefinate periods
SE: drosiness, ataxie, LEUKOPENIA, HypoT (safety)
Hydroxyzine (Vistaril)
(Atarax)
Herbal similar to a Benzo
*suppresses emotional excitability, gives mild euphoria
*don't take w/ CNS depressants
*NOT for pregnant or lactating women or kids <12yrs
SE: impaired thinking, judgement, motor reflexes, vision, dec plasma proteins, thrombocytopenia, leukocytopenia, dyspnea, pulmonary HTN
Kava
Herbal used for prevention and tx of "jet lag" and insomnia
*CI in hepatic insufficiency, hx of cerebrovascular dz, depression, and neurologic disorders
Melatonin
General SE for antacids
Constipation, diarrhea
Acid rebound between doses
Metabolic acidosis
NC for antacids
Reduces absorption of tetracyclines, quinolnes, phenothiazides, iron preps, INH
May decrease effectiveness of oral contraceptives and salicylates
Monitor bowel fnct (can cause bowel addiction)
Give 1-2 hrs after eating and other meds
F&E balance
Antacids
*contain sodium (monitor for sodium restricted diet)
*encourage fluids
*Monitor for signs of phosphate deficiency (malaise, weakness, tremors, bone pain)
Aluminum hydroxide gel (Amphojel)
Calcium carbonate (Titralac)
Aluminum hydroxide and magnesium trisilicate
NC for Magnesium hydroxide (Milk of Magnesia)
Store at room temp w/ tight lid (prevent absorption of CO2)
Can lead to dependence with prolonged use
CAUTION w/ renal dz
NC for Maalox
slight laxative effect
encourage fluids
CAUTION w/ renal dz
General SE for antidysrhythmics
Hypotension (SAFETY with position change)
BradyC
Confusion
Class 1A Antidysrhythmics
SE: HypoT and Heart Failure
NC: Monitor BP, widening PR, QRS or QT intervals
Toxic SE have limited use
Procainamide (Pronestyl)
Disopyramine (Norpace)
Class 1B Antidysrhythmics
SE: slurred speech, confusion, drowsiness, confusion, seizures, HypoT, BradyC
NC: Monitor for CNS SE
Monitor BP and heart rate and cardiac rhythm
Lidocaine (xylocaine)
Mexiletine hydrochloride (Mexitil)
Tocainide hydrochloride (Tonocard)
Beta blockers
SE: BRONCHOSPASM (airway issues), BradyC, HypoT (safety)
NC: monitor apical heart rate (for 1 min), cardiac rhythm, BP, assess for SOB and wheezing
Propanolol (Inderal)
Acebutolol (Sectral)
Esmolol hydrochloride (Brevibloc)
Sotalol hydrochloride (Betapace)
Class III Antidysrhythmics
*unique SE: photosensitivity and photophobia (need sunglasses and sunscreen)
Amiodarone hydrochloride (Cordarone)
Ibutilide fumarate (Covert)
Dofetilide (Tikosyn)
Antidysrhythmics
*apical pulse and BP
*orthostatic precautions
*report signs of HF
Verapamil (Calan)
Diltiazem hydrochloride (Cardizem)
Antibiotics: TX of severe systemic infections of CNS, respiratory, GI, urinary tract, bone, skin, soft tissues, acute pelvic inflammatory dz, TB (streptomycin)
Gentamicin (Garamycin)
Neomycin
Streptomycin
Tobramycin (Tobrax)
Amikacin (Amikin)
SE for Gentamicin, Neomycin, Streptomycin, Tobramycin, Amikacin (Antibiotics)
Ototoxicity, Nephrotoxicity, Anorexia, nausea, vomiting, diarrhea
NC for Gentamicin, Neomycin, Streptomycin, Tobramycin, Amikacin (Antibiotics)
Check 8th cranial nerve fnct (HEARING)
Check renal fnct (BUN, creatinine)
Usually prescribed for 7-10 days (take till gone!)
Encourage fluids (3000mL/day)
Small, frequent meals
C&S prior to hanging med
Check expiration date (some become toxic)
SE of cephalosporins (antibiotics)(general)
Abdominal pin, NVD, inc risk of bleeding, hypoprothrombinemia, bone marrow depression, rash, superinfections, thrombophlebitis (IV), abscess formation (IM,IV)
NC for cephalosporins (antibiotics) (general)
W/FOOD (unique for antibiotics)
liquid form to kids
Vitamin K available for hypoprothrombinemia
No ETOH during & 3 days post med
Cross allergy w/ penicillins
Monitor renal & hepatic fnct
Monitor for thrombophlebitis
SE for Antibiotics to treat infection by E. coli, chronic bacteria, post-exposure to anthrax:
Ciprofloxacin (Cipro), Levofloxacin (Levequin), Norfloxacin (Noroxin)
HA, Nausea, Diarrhea (destroys normal flora), Elevated BUN, AST, ALT, serum creatinine, alkaline phosphatase
Dec WBC and hematocrit
Rash
Photosensitivity
NC for Antibiotics to treat infection by E. coli, chronic bacteria, post-exposure to anthrax:
Ciprofloxacin (Cipro), Levofloxacin (Levequin), Norfloxacin (Noroxin)
C&S prior to starting
1h before or 2h after meals w/ glass of water
Fluids (3,000mL/day)
Full course of therapy
Iron prep and antacids interfere w/ absorption
SE of Vancomycin (antibiotic)
Thrombophlebitis
Abscess formation
Nephrotoxicity
Ototoxicity
NC of Vancomycin (antibiotic)
Renal & Hearing fnct (monitor)
Give IV; peak 5 min, duration 12-24 hrs
Avoid extravascation
"Red man syndrome" -> give antihistamine - dec BP, flushing of face and neck
Contact MD if signs of superinfection (sore throat, fever, fatigue)
Antibiotics given when pt is allergic to PCN
Erthromycin (Erythrocin)
Azethromycin (Zithromax)
NC for Erthromycin (Erythrocin) &
Azethromycin (Zithromax) - (Antibiotics given when pt is allergic to PCN)
*Confusion (unique for antibiotics)
1h before or 2-3h after meals w/ full glass of water
take around the clock
monitor liver fnct
NC for Penicillins
C&S prior to tx
if IV -> monitor lytes & cardiac status
rotate injection sites
mouth care
if diarrhea -> give yogurt or buttermilk
**Airway mgmt if allergic reaction
SE unique to antibiotics for Sulfonamides
Sulfisoxazole (Gantrisin)
Sulfasalazine (Azulfidine)
Trimethoprim/Sulfamethoxazole (Bactrim, Septra)
peripheral neuropathy
crystalluria, proteinuria
photosensitivity
General NC/SE for antibiotics
GI upset/Stomatitis
nephrotoxcity
C&S prior to starting
empty stomach with water (all but cephlosporins)
Fluids
Take full course
Unique SE for Tetracyclines (antibiotics)

Doxycycline (Vibramycin)
Minocycline (Minocin)
Tetracycline HCL (Panmycin)
Don't take during pregnancy: discoloration and inadequate calcification of primary teeth of fetus
phototoxic reactions (sunburn type)
Don't take w/ antacids, milk, iron preps (separate by 3h)
Protect from sunlight
Use additional contraception method in addition to oral contraceptives
Important NC for anti-impotence (vasoD's)

Sildenafil (Viagra)
Vardenafil (Levitra)
Tadalafil (Cialis)
Never take with nitrates - could have fatal hypoT
No grapefruit juice
CI w/ glaucoma
General SE/NC for Anticholinergics
Blurred vision
Dry mouth
Urinary retention
Changes in heart rate
CI w/ glaucoma
Heparin antidote
Protamine sulfate w/in 30 min
Warfarin (Coumadin) antidote
Vitamin K
(avoid foods high in vitamin K: GLV, pork, rice, yogurt, cheeses, fish, milk)
Herbal and vitamin interactions with anticoagulants

Heparin
Lovenox
Warfarin (Coumadin)
Garlic, ginger, ginko INC effect (inc bleeding)
Vitamin E INC warfarin's effect

Ginseng, alfalfa and Vit C may DEC effect
Chamomile may interfere
General SE for Anticonvulsants
Cardiovascular DEPRESSION
Respiratory DEPRESSION
Agranulocytosis
Aplastic anemia
General NC for Anticonvulsants
Tolerance w/ long-term use
WEEN, don't discontinue abruptly
CAUTION w/ MAOI's, antipsychotics (lowers seizure threshold)
CNS/Resp DEPRESSANT (safety)
Important NC for Fosphenytoin (Cerebyx) (Anticonvulsant)
Contact HCP if rash develops
Important NC for Levetiracetam (Keppra) (anticonvulsant)
Watch for suicidal ideation
Important/unique NC for Phenytoin sodium (Dilantin)**
(anticonvulsant)
IV admin: may lead to CARDIAC ARREST - have resuscitation equipment at hand
Never mix w/ any other drug or dextrose IV (own port)
Oral hygiene
Inc vitamin D intake - exposure to sunlight may be necessary w long-term use
Take w/ at least 1/2 glass water or meals to minimize GI irritation
Inform: red-brown or pink discoloration of sweat and urine
Important NC for Phenobarbital (Luminal) (anticonvulsant)
Nystagmus ("dancing eyes" - involuntary eye movements) may indicate early toxcity
Folic acid supplements for long-term use
Important NC for Magnesium sulfate (anticonvulsant)
Evaluate deep tendon reflexes
Before each dose, knee jerks should be tested
HyptoT is a SE (safety)
Unique NC for Valporic acid (Depakote) (anticonvulsant)
Don't take with carbonated drinks
Monitor platelets, bleeding time, and liver fnct
Important NC with Lamotrigine (Lamictal) (Anticonvulsant)
Life-threatening rash when given with Valporic acid (Depakote)
Important/unique NC for Topiramate (Topamax) (anticonvulsant)
Increased risk for renal calculi
Stop drug immediately if eye problems - could lead to permanent damage
General NC for antidepressants (SSRIs)

Fluoxetine (Prozac)
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluvoxamine (Luvox)
Paroxetine (Paxil)
Sertaline (Zoloft)
Take in AM
4 wks for full effect (suicide precautions)
DO NOT give w/ MAOI's (serotonin syndrome risk)
pink urine
Monitor for thrombocytopenia, leukopenia, anemia
Unique NC/SE for Tricyclics (antidepressants)

Amitriptyline (Elavil)
Imipramine (Tofranil)
Norpramin (Desipramine)
Orthostatic HypoT
Bone marrow depression
photosensitivity
anticholinergic effects
sedation
Info for Rapid-acting insulin
Lispro (Humalog)
Aspart (NovoLog)

"Logs roll rapidly"
Onset:5-15min (should eat w/in this time)
Peak: 40min-1hr
Duration: 3-6hr
Info for short-acting insulin (Regular)

Humulin R, Vovolin R, Iletin II Regular
Only type of insulin that can be given IV
Clear solution
Give 20-30 min before meal
Onset: 30-60min
Peak: 2-3hr
Duration: 4-8hr
SE of Glucagon (med given for HypoG)
HypoT
Bronchospasm
Dizziness
Lithium (for manic episode in bipolar disorder) info & therapeutic blood target level
1-1.5 mEq/L
Check 2-3x/wk when started and monthly on maintenance
draw in AM prior to dose
FLUID (2,500-3,000mL/day) & SODIUM intake important
Digoxin (Lanoxin) digitalizing dose (oral)
0.5-0.75mg po
Then 0.25 mg po q 6-8hrs to a total dose of 1-1.5mg
Digoxin (Lanoxin) digitalizing dose (IV)
0.25-0.5mg IV
Then 0.25mg IV to a total dose of 1.0mg
Therapeutic blood level for Digoxin
0.5-2 nanograms/mL
(Toxic = >2)
Antidote for Digoxin
Digibind (give for toxicity)