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234 Cards in this Set

  • Front
  • Back
Afterload
the amount of resistance to ejection of blood from the ventricle
apical impulse
(also called point of maximum impulse [PMI]): impulse normally palpated at the fifth intercostal space, left midclavicular line; caused by contraction of the left ventricle
baroreceptors
nerve fibers located in the aortic arch and carotid arteries that are responsible for reflex control of the blood pressure
cardiac catheterization
an invasive procedure used to measure cardiac chamber pressures and assess patency of the coronary arteries
cardiac conduction system
specialized heart cells strategically located throughout the heart that are responsible for methodically generating and coordinating the transmission of electrical impulses to the myocardial cells
cardiac output
amount of blood pumped by each ventricle in liters per minute; normal cardiac output is 5 L per minute in the resting adult heart
cardiac stress test
a test used to evaluate the functioning of the heart during a period of increased oxygen demand
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
depolarization
electrical activation of a cell caused by the influx of sodium into the cell while potassium exits the cell
diastole
period of ventricular relaxation resulting in ventricular filling
ejection fraction
percentage of the end-diastolic blood volume ejected from the ventricle with each heartbeat
hemodynamic monitoring
use of monitoring devices to measure cardiovascular function
hypertension
blood pressure greater than 140/90 mm Hg
hypotension
a decrease in blood pressure to less than 100/60 mm Hg
international normalized ratio (INR)
a standard method for reporting prothrombin levels, eliminating the variation in test results from laboratory to laboratory
murmurs
sounds created by abnormal, turbulent flow of blood in the heart
myocardial ischemia
condition in which heart muscle cells receive less oxygen than needed
myocardium
muscle layer of the heart responsible for the pumping action of the heart
normal heart sounds
sounds produced when the valves close; normal heart sounds are S1 (atrioventricular valves) and S2 (semilunar valves)
postural (orthostatic) hypotension
a significant drop in blood pressure (usually 10 mm Hg systolic or more) after an upright posture is assumed
ejection fraction
percentage of the end-diastolic blood volume ejected from the ventricle with each heartbeat
hemodynamic monitoring
use of monitoring devices to measure cardiovascular function
hypertension
blood pressure greater than 140/90 mm Hg
hypotension
a decrease in blood pressure to less than 100/60 mm Hg
international normalized ratio (INR)
a standard method for reporting prothrombin levels, eliminating the variation in test results from laboratory to laboratory
murmurs
sounds created by abnormal, turbulent flow of blood in the heart
myocardial ischemia
condition in which heart muscle cells receive less oxygen than needed
myocardium
muscle layer of the heart responsible for the pumping action of the heart
normal heart sounds
sounds produced when the valves close; normal heart sounds are S1 (atrioventricular valves) and S2 (semilunar valves)
postural (orthostatic) hypotension
a significant drop in blood pressure (usually 10 mm Hg systolic or more) after an upright posture is assumed
preload
degree of stretch of the cardiac muscle fibers at the end of diastole
pulmonary vascular resistance
resistance to right ventricle ejection of blood
radioisotopes
unstable atoms that emit small amounts of energy in the form of gamma rays; used in cardiac nuclear medicine studies
repolarization
return of the cell to resting state, caused by reentry of potassium into the cell while sodium exits the cell
sinoatrial (SA) node-
primary pacemaker of the heart, located in the right atrium
stroke volume
amount of blood ejected from the ventricle per heartbeat; normal stroke volume is 70 mL in the resting heart
systemic vascular resistance
resistance to left ventricle ejection
systole
period of ventricular contraction resulting in ejection of blood from the ventricles into the pulmonary artery and aorta
telemetry
the process of continuous electrocardiographic monitoring by the transmission of radiowaves from a battery-operated transmitter worn by the patient
Venodilating agent
medication causing dilation of veins
spironolactone
potassium sparing diuretic
Sodium Na+
135-145 mEq/L
Potassium K+
3.5-5.0 mEq/L
Calcium Ca+
4.5-5.0 mg/dL
Magnesium Mg++
1.3-2.5 mEq/L
Blood urea nitrogen (BUN)
10-20 mg/dL
Creatinine
0.7-1.4 mg/dL
BUN Creatinine Ratio
10:1-20:1
Glucose
60 - 110 mg/dL
Partial thromboplastin time (PTT)
effect of heparin
The heparin dose is changed so that the PTT or APTT result is about 1.5 to 2.5 times the normal value.


Normal:60–70 seconds
Activated partial thromboplastin time (aPTT)
effect of heparin
25-35 seconds
The heparin dose is changed so that the PTT or aPTT result is about 1.5 to 2.5 times the normal value.
Prothrombin time (PT)
effect of coumadin
10-14 seconds
International Normalized Ratio (INR)
effect of coumadin
2.0 to 3.5
RBC
4.2 – 5.2 million
WBC
4,500-11,000 /cu mm
Hemoglobin (hgb)
Males: 13 – 18 gm/dL
Females: 12-16 gm/dL
Hematocrit (hct)
Males: 42-52%
Females: 35-47%
Platelets
150,000-450,000/cu mm
Ablation
purposeful destruction of heart muscle cells, usually in an attempt to control a dysrhythmia
Antiarrhythmic
a medication that suppresses or prevents a dysrhythmia
Automaticity
ability of the cardiac cells to initiate an electrical impulse
Cardioversion
electrical current administered in synchrony with the patient's own QRS complex to stop a dysrhythmia
Chronotropy
rate of impulse formation
Conduction
transmission of electrical impulses from one cell to another
Defibrillation
electrical current administered to stop a dysrhythmia, not synchronized with the patient's QRS complex
Depolarization
process by which cardiac muscle cells change from a more negatively charged to a more positively charged intracellular state
Dromotropy
conduction velocity
Dysrhythmia
(also referred to as arrhythmia)-disorder of the formation or conduction (or both) of the electrical impulse within the heart, altering the heart rate, heart rhythm, or both and potentially causing altered blood flow
Implantable cardioverter defibrillator (ICD)-
a device implanted into the chest to treat dysrhythmias
Inhibited
in reference to pacemakers, term used to describe the pacemaker withholding an impulse (not firing)
Inotropy
force of myocardial contraction
P wave
the part of an electrocardiogram (ECG) that reflects conduction of an electrical impulse through the atrium; atrial depolarization

if absent impulse originates somewhere else than SA node

ATRIAL electrical activity
Paroxysmal
a dysrhythmia that has a sudden onset and/or termination and is usually of short duration
PP interval
the duration between the beginning of one P wave and the beginning of the next P wave; used to calculate atrial rate and rhythm
PR interval
the part of an ECG that reflects conduction of an electrical impulse from the sinoatrial (SA) node through the atrioventricular (AV) node

This time delay before contraction allows the atria to contract (atrial kick) and fill the ventricles.
Proarrhythmic
an agent (eg, a medication) that causes or exacerbates a dysrhythmia
QRS complex
the part of an ECG that reflects conduction of an electrical impulse through the ventricles; ventricular depolarization
QT interval
the part of an ECG that reflects the time from ventricular depolarization through repolarization
Repolarization
process by which cardiac muscle cells return to a more negatively charged intracellular condition, their resting state
Sinus rhythm
electrical activity of the heart initiated by the sinoatrial (SA) node
ST segment
the part of an ECG that reflects the end of the QRS complex to the beginning of the T wave
Supraventricular tachycardia (SVT)-
a rhythm that originates in the conduction system above the ventricles
TP interval
the part of an ECG that reflects repolarization of the ventricles
T wave
the part of an ECG that reflects repolarization of the ventricles
Triggered
in reference to pacemakers, term used to describe the release of an impulse in response to some stimulus
U wave
the part of an ECG that may reflect Purkinje fiber repolarization; usually it is not seen unless a patient's serum potassium level is low
Ventricular tachycardia (VT)
a rhythm that originates in the ventricles
acute coronary syndrome (ACS)
signs and symptoms that indicate unstable angina or acute myocardial infarction
angina pectoris
chest pain brought about by myocardial ischemia
angiotensin-converting enzyme (ACE) inhibitors
medications that inhibit the angiotensin-converting enzyme
atherosclerosis
abnormal accumulation of lipid deposits and fibrous tissue within arterial walls and lumen
atheroma
fibrous cap composed of smooth muscle cells that forms over lipid deposits within arterial vessels and that protrudes into the lumen of the vessel, narrowing the lumen and obstructing blood flow; also called plaque
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
coronary artery bypass graft (CABG)
a surgical procedure in which a blood vessel from another part of the body is grafted onto the occluded coronary artery below the occlusion in such a way that blood flow bypasses the blockage
creatine kinase (CK)
an enzyme found in human tissues; one of the three types of CK is specific to heart muscle and may be used as an indicator of heart muscle injury
high-density lipoprotein (HDL)
a protein-bound lipid that transports cholesterol to the liver for excretion in the bile; composed of a higher proportion of protein to lipid than low-density lipoprotein; exerts a beneficial effect on the arterial wall
ischemia
insufficient tissue oxygenation
low-density lipoprotein (LDL)
a protein-bound lipid that transports cholesterol to tissues in the body; composed of a lower proportion of protein to lipid than high-density lipoprotein; exerts a harmful effect on the arterial wall
metabolic syndrome
a cluster of metabolic abnormalities including insulin resistance, obesity, dyslipidemia, and hypertension that increase the risk of cardiovascular disease
myocardial infarction (MI)
death of heart tissue caused by lack of oxygenated blood flow; if acute, abbreviated as AMI
percutaneous coronary intervention (PCI)
an invasive procedure in which a catheter is placed in a coronary artery, and one of several methods is employed to remove or reduce a blockage within the artery
percutaneous transluminal coronary angioplasty (PTCA)
a type of percutaneous coronary intervention in which a balloon is inflated within a coronary artery to break an atheroma and open the vessel lumen, improving coronary artery blood flow
primary prevention
interventions taken to prevent the development of coronary artery disease
secondary prevention
interventions taken to prevent the advancement of existing coronary artery disease
stent
a woven mesh that provides structural support to a coronary vessel, preventing its closure
sudden cardiac death
immediate cessation of effective heart activity
thrombolytic
an agent or process that breaks down blood clots
troponin
myocardial protein; measurement is used to assess heart muscle injury
allograft
heart valve replacement made from a human heart valve (synonym: homograft)
annuloplasty
repair of a cardiac valve's outer ring
aortic valve
semilunar valve located between the left ventricle and the aorta
autograft
heart valve replacement made from the patient's own heart valve (eg, the pulmonic valve is excised and used as an aortic valve)
cardiomyopathy
disease of the heart muscle
chordoplasty
repair of the stringy, tendinous fibers that connect the free edges of the atrioventricular valve leaflets to the papillary muscles
commissurotomy
splitting or separating fused cardiac valve leaflets
heterograft
heart valve replacement made of tissue from an animal heart valve (synonym: xenograft)
homograft
heart valve replacement made from a human heart valve (synonym: allograft)
leaflet repair
repair of a cardiac valve's movable “flaps” (leaflets)
mitral valve
atrioventricular valve located between the left atrium and left ventricle
orthotopic transplantation
the recipient's heart is removed, and a donor heart is grafted into the same site; the patient has one heart
prolapse (of a valve)
stretching of an atrioventricular heart valve leaflet into the atrium during systole
pulmonic valve
semilunar valve located between the right ventricle and the pulmonary artery
regurgitation
backward flow of blood through a heart valve
stenosis
narrowing or obstruction of a cardiac valve's orifice
total artificial heart
mechanical device used to aid a failing heart, assisting the right and left ventricles
tricuspid valve
atrioventricular valve located between the right atrium and right ventricle
valve replacement
insertion of a device at the site of a malfunctioning heart valve to restore blood flow in one direction through the heart
valvuloplasty
repair of a stenosed or regurgitant cardiac valve by commissurotomy, annuloplasty, leaflet repair, or chordoplasty (or a combination of procedures)
ventricular assist device
mechanical device used to aid a failing right or left ventricle
xenograft
heart valve replacement made of tissue from an animal heart valve (synonym: heterograft)
anuria
urine output of less than 50 mL per 24 hours
ascites
an accumulation of serous fluid in the peritoneal cavity
cardiac output (CO)
the amount of blood pumped out of the heart in 1 minute
cardiac resynchronization therapy (CRT)
a treatment for heart failure in which a device paces both ventricles to synchronize contractions
compliance
the elasticity or amount of “give” when blood enters the ventricle
congestive heart failure (CHF)
a fluid overload condition (congestion) associated with heart failure
contractility
the force of ventricular contraction; related to the number and state of myocardial cells
diastolic heart failure
the inability of the heart to pump sufficiently because of an alteration in the ability of the heart to fill; current term used to describe a type of heart failure
dyspnea on exertion (DOE)
shortness of breath that occurs with exertion
ejection fraction (EF)
percentage of blood volume in the ventricles at the end of diastole that is ejected during systole; a measurement of contractility
heart failure (HF)
the inability of the heart to pump sufficient blood to meet the needs of the tissues for oxygen and nutrients; signs and symptoms of pulmonary and systemic congestion may or may not be present
implantable cardioverter defibrillator (ICD)
a device implanted in patients with ventricular dysrhythmias that detects and treats dysrhythmias
left-sided heart failure (left ventricular failure)
inability of the left ventricle to fill or pump (empty) sufficient blood to meet the needs of the tissues
for oxygen and nutrients; traditional term used to describe patient's symptoms of heart failure

fluid in lungs
oliguria
diminished urine output; less than 400 mL per 24 hours
orthopnea
shortness of breath when lying flat
paroxysmal nocturnal dyspnea (PND)
shortness of breath that occurs suddenly during sleep
Which of the following waveforms on the ECG is indicative of ventricular repolarization?
T wave
Rationale: The T wave represents ventricular repolarization (when the cells regain a negative charge; also called the resting state).
Which of the following waveforms on the ECG is indicative of atrial depolarization?
P wave
Rationale: The P wave represents the electrical impulse starting in the sinus node and spreading through the atria. It is normally 2.5 mm or less in height and 0.11 seconds or less in duration.
All of the following are characteristics of sinus bradycardia except:
a. PR interval between .12 and .20 seconds
b. Atrial rate greater than 100
c. Regular rhythm
d. Normal QRS
Atrial rate greater than 100
Rationale: In sinus bradycardia, the ventricular and atrial rates are less than 60 in the adult.
Which of the following is a possible cause of loss of capture in a pacemaker?
a. Output too high
b. Battery depletion
c .Disconnected wires
d. Septal perforation
Battery depletion
Rationale: Possible causes of loss of capture in a pacemaker include inadequate stimulus, catheter malposition, battery depletion, and electronic insulation break.
Defibrillation is the treatment of choice for which of the following cardiac rhythms?
a. Pulseless ventricular tachycardia
b. Sinus bradycardia
c. A-flutter
d. Sinus tachycardia
Pulseless ventricular tachycardia
Rationale: Defibrillation is used in emergency situations as the treatment of choice for ventricular fibrillation and pulseless VT, the most common cause of abrupt loss of cardiac function and sudden cardiac death.
acute coronary syndrome (ACS)
signs and symptoms that indicate unstable angina or acute myocardial infarction
angiotensin-converting enzyme (ACE) inhibitors
medications that inhibit the angiotensin-converting enzyme
atherosclerosis
abnormal accumulation of lipid deposits and fibrous tissue within arterial walls and lumen
atheroma
fibrous cap composed of smooth muscle cells that forms over lipid deposits within arterial vessels and that protrudes into the lumen of the vessel, narrowing the lumen and obstructing blood flow; also called plaque
contractility
ability of the cardiac muscle to shorten in response to an electrical impulse
coronary artery bypass graft (CABG)
a surgical procedure in which a blood vessel from another part of the body is grafted onto the occluded coronary artery below the occlusion in such a way that blood flow bypasses the blockage
creatine kinase (CK)
an enzyme found in human tissues; one of the three types of CK is specific to heart muscle and may be used as an indicator of heart muscle injury
high-density lipoprotein (HDL)
a protein-bound lipid that transports cholesterol to the liver for excretion in the bile; composed of a higher proportion of protein to lipid than low-density lipoprotein; exerts a beneficial effect on the arterial wall
ischemia
insufficient tissue oxygenation
low-density lipoprotein (LDL)
a protein-bound lipid that transports cholesterol to tissues in the body; composed of a lower proportion of protein to lipid than high-density lipoprotein; exerts a harmful effect on the arterial wall
metabolic syndrome
a cluster of metabolic abnormalities including insulin resistance, obesity, dyslipidemia, and hypertension that increase the risk of cardiovascular disease
myocardial infarction (MI)
death of heart tissue caused by lack of oxygenated blood flow; if acute, abbreviated as AMI
percutaneous coronary intervention (PCI)
an invasive procedure in which a catheter is placed in a coronary artery, and one of several methods is employed to remove or reduce a blockage within the artery
percutaneous transluminal coronary angioplasty (PTCA)
a type of percutaneous coronary intervention in which a balloon is inflated within a coronary artery to break an atheroma and open the vessel lumen, improving coronary artery blood flow
primary prevention
interventions taken to prevent the development of coronary artery disease
secondary prevention
interventions taken to prevent the advancement of existing coronary artery disease
stent
a woven mesh that provides structural support to a coronary vessel, preventing its closure
sudden cardiac death
immediate cessation of effective heart activity
thrombolytic
an agent or process that breaks down blood clots
troponin
myocardial protein; measurement is used to assess heart muscle injury
allograft
heart valve replacement made from a human heart valve (synonym: homograft)
annuloplasty
repair of a cardiac valve's outer ring
aortic valve
semilunar valve located between the left ventricle and the aorta
autograft
heart valve replacement made from the patient's own heart valve (eg, the pulmonic valve is excised and used as an aortic valve)
cardiomyopathy
disease of the heart muscle
chordoplasty
repair of the stringy, tendinous fibers that connect the free edges of the atrioventricular valve leaflets to the papillary muscles
commissurotomy
splitting or separating fused cardiac valve leaflets
heterograft
heart valve replacement made of tissue from an animal heart valve (synonym: xenograft)
homograft
heart valve replacement made from a human heart valve (synonym: allograft)
leaflet repair
repair of a cardiac valve's movable “flaps” (leaflets)
mitral valve
atrioventricular valve located between the left atrium and left ventricle
orthotopic transplantation
the recipient's heart is removed, and a donor heart is grafted into the same site; the patient has one heart
prolapse (of a valve)
stretching of an atrioventricular heart valve leaflet into the atrium during systole
pulmonic valve
semilunar valve located between the right ventricle and the pulmonary artery
regurgitation
backward flow of blood through a heart valve
stenosis
narrowing or obstruction of a cardiac valve's orifice
total artificial heart
mechanical device used to aid a failing heart, assisting the right and left ventricles
tricuspid valve
atrioventricular valve located between the right atrium and right ventricle
valve replacement
insertion of a device at the site of a malfunctioning heart valve to restore blood flow in one direction through the heart
valvuloplasty
repair of a stenosed or regurgitant cardiac valve by commissurotomy, annuloplasty, leaflet repair, or chordoplasty (or a combination of procedures)
ventricular assist device
mechanical device used to aid a failing right or left ventricle
xenograft
heart valve replacement made of tissue from an animal heart valve (synonym: heterograft)
risk factors for primary HTN
obesity, stress, high intake of sodium or saturated fat, family hx
risk factors for secondary HTN
diabetes mellitus, head injury, hormonal contraceptives
compare intra-arterial & cuff blood pressure readings
Intra arterial readings s/b at least 10 mmHg higher than cuff readings
ECG strip - cardiac tamponade
suppresses the amplitude of the QRS reflex on an ECG
arterial baroreceptors are found
carotid sinus, aorta & right ventricular wall
Heparin is counteracted by:
protamine sulfate
Paroxysmal nocturnal dyspnea (PND)
shortness of breath that occurs suddenly during sleep
Pericardiocentesis
procedure that involves aspiration of fluid from the pericardial sac
Pericardiotomy
surgically created opening of the pericardium
Preload
the amount of myocardial stretch just before systole caused by the volume of blood presented to the ventricle
Pulmonary edema
abnormal accumulation of fluid in the interstitial spaces or in the alveoli of the lungs
Pulseless electrical activity (PEA)
condition in which electrical activity is present but there is not an adequate pulse or blood pressure because of ineffective cardiac contraction or circulating blood volume
Pulsus paradoxus
systolic blood pressure of more than 10 mm Hg higher during exhalation than during inspiration; difference is normally less than 10 mm Hg
Right-sided heart failure (right ventricular failure)
inability of the right ventricle to fill or pump (empty) sufficient blood to the pulmonary circulation
Stroke volume (SV)
amount of blood pumped out of the ventricle with each contraction
Systolic heart failure
inability of the heart to pump sufficiently because of an alteration in the ability of the heart to contract; current term used to describe a type of heart failure
Paroxysmal nocturnal dyspnea (PND)
shortness of breath that occurs suddenly during sleep
Pericardiocentesis
procedure that involves aspiration of fluid from the pericardial sac
Pericardiotomy
surgically created opening of the pericardium
Preload
the amount of myocardial stretch just before systole caused by the volume of blood presented to the ventricle
Pulmonary edema
abnormal accumulation of fluid in the interstitial spaces or in the alveoli of the lungs
Pulseless electrical activity (PEA)
condition in which electrical activity is present but there is not an adequate pulse or blood pressure because of ineffective cardiac contraction or circulating blood volume
Pulsus paradoxus
systolic blood pressure of more than 10 mm Hg higher during exhalation than during inspiration; difference is normally less than 10 mm Hg
Right-sided heart failure (right ventricular failure)
inability of the right ventricle to fill or pump (empty) sufficient blood to the pulmonary circulation

swelling & edema
Stroke volume (SV)
amount of blood pumped out of the ventricle with each contraction
Systolic heart failure
inability of the heart to pump sufficiently because of an alteration in the ability of the heart to contract; current term used to describe a type of heart failure
Normal rhythm or sinus rhythm
ECG
regular rhythm
P waves before QRS
atrial rate 60-100
PR interval 0.12-0.20 sec
QRS width < 0.12
ventricular rate 60-100
Sinus bradycardia
ECG
regular or slightly irregular rhythm
P waves before QRS
atrial rate < 60
PR interval 0.12-0.20 sec
QRS width < 0.12
ventricular rate < 60
Sinus tachycardia
ECG
regular rhythm
P waves before QRS, can be on top of T waves
atrial rate 100-150
PR interval 0.12-0.20 sec
QRS width < 0.12
ventricular rate 100-150
Sinus arrhythmia
ECG
rate faster with inspiration, slower with expiration
irregular rhythm
P waves before QRS
atrial rate bradycardia or normal sinus
PR interval 0.12-0.20 sec
QRS width < 0.12
ventricular rate bradycardia or normal sinus
Sinus arrest (sinus pause)
ECG
Problem with SA node, pause where no waves occur
irregular rhythm
P waves before QRS
atrial rate usually bradycardia
PR interval 0.12-0.20 sec
QRS width < 0.12
ventricular rate usually normal sinus
Premature atrial Contraction (PAC)

ECG
Beat originates in atria, not in sinus node
Irregular rhytm
P waves early beat, looks different
Atrial tachycardia
ECG
P waves may be on top of T waves
regular rhythm
P waves uniform shape (called supravetricular tachycardia if P waves arent visible)
atrial rate 150-250
Ventricular rate depends on AV conduction ratio
Atrial flutter
ECG
regular rhythm
P waves flutter wave
atrial rate 250-350
PR interval hard to measure
QRS width < 0.12
ventricular rate depends on AV conducgion ation
Atrial fibrillation
ECG
irregular rhythm
P waves coarse or fine fibrillating waves
atrial rate >350
PR interval none
QRS width < 0.12
ventricular rate varies, <100 controlled ventricular response
Idioventricular rhythm (IVR)
ECG
Lethal, pacemaker cells in the ventricles start the rhythm
regular rhythm
P waves none
atrial rate cant be determined
PR interval none
QRS width >0.12
ventricular rate 20-40
Ventricular tachycardia (VT)
ECG
Lethal
regular rhyth
p waves none
atrial rate none
PR interval none
QRS width >0.12
ventricular rate 100 - 170
if 150 - 300 = ventricular flutter
Vetricular fibrillation (VF)
ECG
lethal
irregular, chaotic rhythm
P waves none
atrial rate cant be determined
PR interval none
QRS width coarse or fine fibrillating waves
ventricular rate cant be determined
Lovenox
low molecular wt heparin
factors that affect CO
blood volume (inc vol = inc preload)(dec vol = dec preload)

tachycardia or bradycardia

changes in BP (inc afterload inc BP, dec afterload dec BP)

dec left ventricular functon
beta blockers
cardioselective metroprolol (Toprol), Lopressor) block beta 1 receptors in heart block sympathetic stimulation to heart, reduce HR, contractility, & stroke volume
used to tx HTN, HF, angina & prevent or tx MI


noncardioselective (propranolol, block both beta 1 in heart & beta 2 receptors in lungs
tx HTN, angina, arrhythmias


reduce HR, slow conduction of impulse thru heart, dec BP, reduce contractility, reduce myocardial O2 consumption