Nbde Part 2 - More Pharma Cards By Sarath

Front 1

The advantages of inhalation sedation with nitrous oxide include all of the following Except rapid biotransformation in the liver.

Back 1

-short recovery time
-rapid onset of action
-Ability to later the depth of sedation from moment to moment.

Front 2

All of the following statements are true about anti neoplastic agents except that the most agents possess a very high therapeutic index.

Back 2

-generally they are not curative,although the success rate is improving.
-generally they do not posess a selective effect on neoplastic cells.
-They are most effective in widely disseminated,non solid tumors.
-They tend to supress function of the bone marrow.

Front 3

All of the following are pharmacologic and toxocologic properties of an aspirin except supression of the immune response

Back 3

- Tinnitus.
- Analgesia.
- Salicylism.
- Anti pyresis.

Front 4

All of the following statements with regard to the prostaglandin are correct except it is derived from essential amino acids.

Back 4

The following are correct which include-
-It is a fatty acid.
-It is thought to be involved in the inflammatory process.
-It is thought to be involved in the reproductive process.
-Its synthesis may be inhibited by non steroidal,ant inflammatory agents.

Front 5

All of the following are examples of iatrogenic diseases except Increased pottasium excretion from hyper aldosteronism.

Back 5

- development of peptic ulcer with chronic use of aspirin.
- developement of gout with the use of thiazide diuretics.
-blood dyscrasias with use of chloramphenicol.
-psuedo membranous colitis from use of clindamycin.

Front 6

Vaso constricting drugs are included in local anesthetic solutions for all the following reasons except to prevent penetration of the local anesthetic at the nerve membrane.

Back 6

- Reduce the toxicity of local anesthetics
-prolong the duaration of action of local anesthetics.
-reduce the rate of vascular absorption of local anesthetics.
-Increase the concentration of the local anesthetic at the nerve membrane.

Front 7

All of the following statements are true regarding intra venous Diazepam except that it has a low therapeutic index.

Back 7

-Produces some degree of amnesia.
-can be employed to terminate most convulsive states.
-Is locally irritating to tissue and may produce thrombo plebitis.
-does not cause significant cardio vascular and respiratory depressions with normal use.

Front 8

Hydero-cortisone may be expected to be effective in each of the following conditions except penicillin anaphylaxis.

Back 8

- Allergic urticaria
-Temporo madibular arthritis.
-Ulcerative oral lesions.
-Acute adreno cortical insufficiency.

Front 9

All of the following symptoms are associated withneostigmine poisioning except- convulsions.

Back 9

-Diarrhea
-salivation.
-Bronchiolar constriction
-Skeletal muscle paralysis.

Front 10

Heparin has all of the following effects except-reduction of circulating fibrinogen.

Back 10

-activation of plasma antithrombin.
-blocking of thrombosplastin generation.
-neutralization of tissue thrombosplastin.
-clearing of alimentary hpyerlipemia.

Front 11

Xerostomia is a common side effect of all of the following
drugs except reserpine.

Back 11

-clonidine.
-imipramine.
-scopolamine.
-promethazine.

Front 12

which of the following is a bactericidal antibiotic used specifically in the treatment of infections caused by pseudomonas species and indole-positive proteus species?

Back 12

Carbenicillin

Front 13

Which of the following charecterizes the mechanism of action of levodopa?

Back 13

It replenishes the otherwise deficient dopamine in patients with parkinsonism.

Front 14

three ml of a local anesthetic consisting of 2% lidocaine with 1:100,000 epinephrine contains how many milligrams of each?

Back 14

60 mg lidocaine,0.03 mg epinephrine.

Front 15

Inhaled amonia acts against syncope by

Back 15

stimulating the sensory nerve endings of the nasal mucosa.

Front 16

Administartaion of a single 1gm dose of aspirin instead of the usual 650 mg will increase.

Back 16

anti inflammatory response to the drug.

Front 17

Verapamil is most efficacious in the treatment of

Back 17

atrial tachycardia.

Front 18

The current drug of choice for treatment of the manic phase of manic depressive psychosis is .

Back 18

lithium

Front 19

The most useful drug to induce salivation is one which has properties that are

Back 19

cholinergic.

Front 20

Compared with the parent compound bio transformation usually results in drugs that are

Back 20

More ionized.

Front 21

Chlotetracycline acts by interfering with .

Back 21

protien synthesis on bacterial but not on mammalian ribosomes

Front 22

alpha 0r beta adrenergic blocking agets act by

Back 22

competteive inhibition of post junctional adrenergic receptors.

Front 23

Which of the following anesthetic drugs produces powerful stimulation of the cerebral cortex?

Back 23

Cocaine

Front 24

Which of the following is afrequent side-effect of anti histamine therapy.

Back 24

Drowsiness

Front 25

Which of the following anti-hypertensive agents is most likely to cause an exaggerated response to an injected catecholamine.

Back 25

Guanethidine.

Front 26

Tetracycline reduces the effectiveness of concomitantly administered penicillin by

Back 26

none of the above which include
- reducing the absorption of penicillin.
-increasing metabolism of penicillin.
-increasing renal excretion of penicillin.
increasing the binding of penicillin to serum proteins.

Front 27

The rapidity of onset of anethesia with an inhalation anetshetic agent is primarily related to its

Back 27

Degree of blood solubility.

Front 28

hepatic "first pass" metabolism of drugs is most significant after which route of administration -

Back 28

Oral route

Front 29

The most serious consequence of systemic local anesthetic toxicity is

Back 29

Post connvulsive central nervous system depression.

Front 30

Local anesthetic drugs suitable for use as topical anesthetic agents in dentistry include

Back 30

Benzocaine and lidocaine

Front 31

The anti psychotic effects of phenothiazines result from

Back 31

blockade of dopaminergic sites in the brain.

Front 32

The primary action of theraupatic doses of digitalis on cardiac muscle is an increase in

Back 32

force of contraction.

Front 33

The maximum allowable adult dose of mepivacaine is 300 mg.how many milliliteres of 2% mepivacine should be injected to attain the maximal doasge in an adult patient

Back 33

15

Front 34

Oral contraceptives exert their primary effect by

Back 34

Inhibiting ovulation

Front 35

Which of the following drugs produces dissociative anesthesia with little respiratory or cardio vascular depression?

Back 35

Ketamine

Front 36

Benzodiazepines produce thier antianxiety effects by modulating which of the following neurohumors?

Back 36

GABA

Front 37

The agent of choice to reverse status epilepticus induced by local anesthetic over dose is

Back 37

Diazepam

Front 38

Which of thefollowing is an irreversible side effect resulting from long term administration of pheno thiazines?

Back 38

Tardive dyskinesia

Front 39

A pharmacologic effect agonist is a chemical substance that

Back 39

Binds to a specific receptor and initiates a response.

Front 40

Digitalis is useful in th treatment of which of th efollowing conditions?

Back 40

all of the below

- Atrial fibrillation
- Congestive heart failure.
- Proxysmal atrial tachycardia

Front 41

Treatment with sulfonamides is less likely to be accompanied by crystalluria if

Back 41

-a mixture of sulfonamides is used