Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
|
Most common site that a secondary metastatic brain tumor came from
|
Lungs
|
|
|
Most common primary malignant CNS tumor in children
|
Medulloblastoma
|
|
|
Most common primary malignant CNS tumor in adults
|
Lung carcinoma leading to adenocarcinoma
|
|
|
Most common benign CNS tumor in children
|
Pilocytic astrocytoma
|
|
|
Most common Benign CNS tumor in adults
|
Meningioma
|
|
|
The two biggest risk factors for a CNS tumor in order are
|
Radiation
Immunosuppresion |
|
|
The most common tumor from radiation and how many years post radiation does it typically develop
|
Meningioma, 8-10 yrs
|
|
|
What grade are cystic tumors typically? Ring enhancing ones?
|
Cystic- low grade
Ring-enhancing high grade |
|
|
Supratentorial vs infratentorial
which is common in adults? which in childre? |
Adults- supratentorial
Children- intratentorial |
|
|
Do low grade tumors closely or poorly resemble the cell tissue of origin?
|
Closely
|
|
|
Among the gliomas which is the most common type of tumor
|
Astrocytoma
|
|
|
Is a diffuse astrocytoma grade IV common?
|
Yes, it is the most common malignant CNS tumor in adults
|
|
|
What does histology of grade IV astrocytoma look like?
|
nuclear atypia, hypercellular, vascular proliferation, pseudo pallisating
|
|
|
what is the most common site of a pilocytic astrocytoma?
|
cerebellum
|
|
|
How does a pilocytic astrocytoma look on imaging?
|
Cystic with a contrast enhancing mural nodule
|
|
|
Describe the defining pathology of a pilocytic astrocytoma
|
Rosenthal Fibers
|
|
|
Most common site of an oligodendroglioma
|
Frontal Lobe
|
|
|
What are key pathologic features of oligodendrogliomas
|
Round Fried Egg Nuclei
Arborizing microvasculature (chicken wire) |
|
|
A favorable genetic alteration for prognosis of oligodendrogliomas is
|
loss of 1p/19q
|
|
|
Ependymomas are predominantly tumors of what age group and in which brain location
|
Children
Posterior Fossa |
|
|
Pathology of ependymomas shows
|
perivascular pseudorosettes
|
|
|
Gangliomas typically occur in the
|
temporal lobe and cause seizures
|
|
|
The location of a medulloblastoma and appearance on radiology
|
Posterior fossa/ cerebellum
Well circumscribed, contrast enhancing, often nodular |
|
|
Which tumor has whorls and psammoma bodies
|
meningiomas
|
|
|
Most common location for a schwannoma
|
cerebellopontine angle
|
|
|
Describe the enchancing characteristics of astrocytomas
Grade II Grade III Grade IV |
Grade II - Non-enhancing
Grade III- Patchy enhancing Grade IV Ring Enchancement |
|
|
Most commonly mutated tumor suppressor gene in diffuse astrocytomas
|
TP53
|
|
|
Pathology shows paranuclear halos, what is the most likely genetic mutation involved?
|
its a Oligodendroglioma, genetics are deletion of 1p/19q
|
|
|
A schwannoma patient likely has what syndrome
|
Neurofibromatosis type 2
|
