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17 Cards in this Set
- Front
- Back
Normal CBC Count, 52% monocytes and lymphocytes. Blood smear shows:
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Large atypical T lymphocytes. EBV
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Elevated AST ALT Alk phos and bilirubin. Confirm diagnosis by:
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Heterophile antibody in patient's serum. Monospot test EBV
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Infectious agent binds to CD21 on b-cell. What are genetic features of infectious agent?
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Enveopled virus with double-stranded linear DNA. EBV
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Pt group most at risk for serious outcome in EBV?
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african children w/ malaria (who also get Burkitt lymphoma)
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EBV in AIDS or HIV
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CNS lymphoma and Non-hodgkin lymphoma (50% are EBV assicuated) in AIDS, Oral hairy leukoplakia in HIV.
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7 year old pt, sore throat, difficulty swallowing, 5 days. Fever, eyrthematous rash on neck, groin, axillae. Red lingual papullae w/ white coat. Exudative tonsillitis. Microbiologic features of this bug?
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Gram-positive cocci in chains, B-hemolytic on sheep blood agar, catalase negitive. Group A Beta-hemolytic streptococci (GABHS), Strep pyogens causing streptococcal pharyngitis
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Virulence factor responsible for rash in GABHS pharyngitis
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erythrogenic toxin
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possible delayed sequelae from strep pyogens pharyngitis
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acute rheumatic fever
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best treatment for strep pharyngitis
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penicillin G (erythromycin if alg)
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9 year old; malase, anorexia, lowgrade fever, delirium. Acute pharyngitis with dirty white membrane. Non-immunized
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corynebacterium diptheriae
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microscopic exam of pharyngeal exudate: numerous small bacteria, metachromatic granules. Specific characteristics of this bug?
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gram-positive pleomorphic rods; aerobic growth on tellurite agar. C. diptheriae
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C. diptheriae produces what for pathology?
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toxin: bacteriophage-coded A-B toxin
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treatment for c. diptheriae
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antitoxin from horse. Immunization prevents.
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13 yr old, sore throat fever, exudative pharyngitis, posterior cervical lymphadenopathy. Conjunctivitis right eye
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Adenovirus
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Adenovirus lab workup
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Culture from nasopharyngeal specimen: fluroescence antibody staining of infected cells
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Adenovirus pulmonary complicaton
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acute respiratory distress syndrome (serotypes 4 and 7)
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adenovirus common source
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community pool, virus stable to external environments.
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