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4 Cards in this Set

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  • Back

Mysathenia Gravis: What is it?

Skeletal muscle weakness caused by a presence of antibodies destroying nAChR at the neuromuscular junction.

Myasthenia Gravis: Signs & Symptoms

> Fatigue




> Skeletal muscle weakness that is worse after exercise, and improves with rest




> Ptosis




> Diplopia

Myasthenia Gravis: Diagnosis

> Physical examination




> Serology for anti-nAChR antibodies (80-96% sensitivity for non-ocular)

Myasthenia Gravis: Management

> AChE inhibitors


e.g pyridostigmine, neostigmine




> Plasmapheresis (severe)