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3 Cards in this Set
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- Back
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What is the brand for phenytoin? It's use? MOA? SE? and therapeutic levels?
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Dilantin; Partial, SE, and tonic clonic seizures; Na+ channel blocker; SAND, acne, hirsutism, osteomalacia, rash, LUPUS, megaloblastic anemia, gingival hyperplasia, and vitamin K deficiency resulting in hemorrage; 10-20 mcg/mL
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What is the brand for felbamate? It's use? MOA? SE? Special Notes?
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Felbatol; partial and Lennox; NMDA-rec antagonist; BBW: Aplastic anemia, hepatotoxic; orphan drug requires a registry and 3A4 inducer and 2C19 inhibitor
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What is the brand for Valproate? It's use? MOA? SE? therapeutic levels? and special notes?
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Depakote; partial, absent, myoclonic, and tonic clonic; Gaba transaminase inhibitor, glutamic acid decarboxylase inducer, inhibitor of Glu release; pancreatitis, alopecia, POS, ammonia, hepatic failure, spina bifida; 50-125 mcg/mL; Inhibitor and displacer of MANY drugs and in peds: liver produces 4-EN-Valp which is hepatotoxic
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