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18 Cards in this Set
- Front
- Back
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the Pharmacological effects of Morphine are (9)?
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1. Mood change
2. Nausea and vomiting 3. Respiratory depression 4. Antitussive 5. Miosis 6. Urinary Retention 7. Inhibits Gonadatropin 8. Cardiovascular 9. G.I. |
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What about opioids causes you to vomit and have nausea? Name a drug used for this purpose
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opioids stimulate the chemorecepor trigger zone (CTZ), use apomorphine.
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what are the mood changes involved in Opioids
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Person in pain will feel euphoria. you can get mental clouding (drowsy, lethargy, apathetic, wants to sleep)
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how does morphine effect respiratory system?
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decreases the response of the brain stem respiratory neurons to C02
also causes Bronchoconstriction by stimulating release of histamine |
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in what form is morphine excreted from the body?
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Glucuronide conjugate
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name the synthetic opioids
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Meperidine
Fentanyl Methadone LAAM PROPOXPHEN DIPHENOXYLATE LOPERAMIDE |
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Name the naturally occuring Opioids
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CODINE
HEROIN OXYCODONE HYDROMORPHONE APOMORPHINE DEXTROMETHORPHAN- |
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important information about Heroin
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Oral absorption is variable, IV more reliable, very lipid soluable
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important information about Oxycodone
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same effects and potency as morphine, but better then morphine taken orally
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important information about Hydromorphone
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same effects as morphine but ten time more potient.
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important information about APOMORPHINE
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has little analgesic activity used to INDUCE VOMITING by direct action with CTZ
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important information about DEXTROMETHORPHAN
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Used as ANTITUSSANT
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important information about MEPERIDINE
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short acting analgesia one tenth the potency of Morphine
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important information about FENTANYL
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used in IV anesthesia 80 TIME MORE POTENT THE MORPHINE. very lipid soluble
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important information about METHADONE
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Same action and potency of as morphine but very long lasting, half life of 15 hours
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what does diphenoxylate and loperamide have in common
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synthetic opioids that are used for anti-diarrhea.
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treatment for opioid overdose
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Naloxone a Pure opioid antagonist
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what is Naltrexone
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pure competitive opioid antagonist with a 24 HOUR DURATION
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