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19 Cards in this Set
- Front
- Back
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Where are the adernal glands
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on top of kidneys
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What are the main roles of Adrenal cortex
Adernal medulla-release CCA |
Aldosterone, Cortisol, Testosterone
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How is aldosterone, cortisol, testoterson syntheisised from
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cholesterol
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What is the MAIN role of aldesterone
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INTRAVASULAR volume
through Na/H20 retention |
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What is the MAIN role of Cortisol
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Glucose metabolism
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Corticosteriods (Cortisol) MOA for in general (for it immune supressing roles)
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inhibits Arachiodonic acid, which inhibits prostaglandin synthesis, and LT
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Corticosteriods can have adverse effects which include
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Edema, Na/+ weight gain (Minercorticodone point)
Corticol-increase BG suppress HPA and cause adrenal insuffiency, and avsaular necorsis |
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Are more dose of steriod requied for pts during STRESS dosing
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YES
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Allergic rhinits is the inflammation of the membranes lining the nasal basses, what symptoms
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rhinorrhea, nasal congestion, snezzing, ithcing
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Two types of allergic rhinits (seasonal and perennial)
Perennial--year round disease |
YES
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What are the most effective agents for allergic rhinits
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intranasal steriods
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Intranasal steriods take a few weeks to work, what also be used for allergic rhinits acute symptoms
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decongestions
antihismtaines (oral, intraocular |
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1st generation anthistamines MOA
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inhibit H1 receptor and cross BBB (anti-cholingeric properties)
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2nd generation anti-histamines do NOT readily cross BB, so
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less sedation
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What is MOA Decongestions (Pseduepedrine, Oxymethazoline, Phenyephine)
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Alpha 2 agoinsts (vasoconstrition)
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What is the maximum amount of time you can use a topical decongestant
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5 days (results in rebound congestion)
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What are the Leukotriene receptor antagoinst
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Montelukast/Zafirlukast
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What is the 5-Lipooxygenase inhibitor
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Zileuton (Zyflo)
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What is Cromolyn (NasalCrom)
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Mast cell stablizer for allergic rhinitis-takes 2-4 week to work
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