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58 Cards in this Set
- Front
- Back
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What are the pregnancy D drugs?
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topamax
pheny phenobarb valproate carbamazepine clonazepam |
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Which AEDs are inducers?
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carbamazepine
oxcarbazepine phenobarb/primidone pheny |
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WHen does topamax become an inducer?
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>200mg/day
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Onfi
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Clobazam
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Doseage forms of k-pin?
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ODT
tablet |
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MOA Epitrol
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Fast Na channel blocker
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2 BBWs for Carbatrol
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1. Skin/ sjs
2. blood dyscrysias: agranulocytosis/ aplastic anemia |
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If you have an allergy to elavil, what drug would be prudent to avoid?
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carbamazepine
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I'm bone marrow suppressed. What AED should I avoid?
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tegretol
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Taking Ca and D would be prudent if you were taking what AEDs?
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Carbamaz
Phenobarb/primidone Pheny Valproic |
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Tegretol therapeutic range?
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4-12
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Zarontin
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Ethosuxamide
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MOA zarontin
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t-type calcium chn blkr
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How is carbamazapine availible
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tabs, xl tabs, soln, caps
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How does ethosuxamide come?
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soln, caps
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How does mysoline come?
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tabs
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How does Luminal come?
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soln, tabs, injection
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Barbital
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Phenobarb
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Therapeutic range luminal?
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20-40 grownups
15-30 kids |
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Mix phenytoin with what?
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NS
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Max pheny infusion rate? WHy, whats the big deal?
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50mg/min; PEG: HoTN + bradyCV
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If the albumin is low the PHT level can get screwy. What is "low"
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<3.5
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How to correct for low albumin & PHT
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pht observed / ((0.2 x alb)+0.1)
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Therapeutic range PHT, total? free?
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10-20; 1-2.5
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Do enteral feeds matter with PHT?
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Yes, must separate by 2 hours either way.
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Can you take calcium and PHT at the same time?
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No. should be separated.
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How fast can you infuse fos?`
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150 PE/ min
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1 mg PE = _____ mg PHT?
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1 mg
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What can you mis fos in?
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either ns or d5
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Use phenytoin as an acronym for the side effects.
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Potent inducer
Hirstutism Enlarhged gums Nystagmus Yukky blood dyscrasias + purple skin (extravisation) Teratogenic Osteoporosis Interference w/ FA absprptin Neuorpathy |
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MOA phenytek
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fast sodium channel blcoker
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MOA mysoline
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pro-drug of phenobarb; enhaces gaba
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How does PHT come?
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injection, suspension, capsules, tabs
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Depacon
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Valproic acid IV
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Depakene
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valproic acid; caps and soln
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Stavzor
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valproic acid capsules
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Depakote
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is a DR tablet; divalproex
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Depakote ER
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is an ER tablet; divalproex. not the same as depakote DR, need to increase dose by ~ 20% of the ER....
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What is a depakote sprinkle?
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divalproex caps that can be opended and sprinkled
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Valproic acid therapeutic range?
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50-100
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Whats' the big deal about giving depakote in pregnancy?
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spina bifidi
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What are the 3 BBWs for depakote?
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pancreatitis
liver pregnacy |
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MOA depakote?
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same as ethosuxamide, which should make sense given that they both treat absense c-zures.
t-type calcium blocker |
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how do you deal with valpric acid hari loss?
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sipplement with zinc
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How does lamictal come?
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ODT & tabz
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GEnerally titrate lamictal q______
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2 weeks
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BBW for lamictal
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1. sjs
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2010 fda warning about lamictal
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aseptic meningitis
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how does keppra come?
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tabs, soln, injeciton
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what drug interactions are we concernd about with keppra?
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there are no DIs
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How do you convert btw triliptal and tegretol?
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1.5-2x cbz dose = oxcarb.
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How does triliptal come?
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susp, tabs
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how does lyrica come?
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susp, caps
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how does gabapentin come?
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susp, caps, tabs
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What drug interactiosn are we worried about with gabapentin/ lyrics?
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there are no significant DIs
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What happens to kids born to mothers on Dopamax?
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clefts
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How does gabapentin and his cousin work?
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alpha 2 delta calcium blocker
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Please review page 804 now.
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Please review page 804 now.
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