Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
40 Cards in this Set
- Front
- Back
|
Drugs in Sulfonylureas (SU)? |
-Glipizide (Glucotrol, Glucotrol XL, Glipizide XL) - Glimepiride (Amaryl) - Glyburide (DiaBeta) SU works by stimulating insulin secretion from the pancreatic beta cells. Do not use with meglitinides due to similar MOA |
|
|
How to take Glipizide IR? |
30 mins before breakfast |
|
|
how to take Meglitinides: Prandin (repaglinide), PrandiMet (repaglinide+metformine) or Starlix (nateglinide)? |
Prandin & PrandiMet --- take 15-30 mins before meals Starlix ---- take 1-30 mins before meals |
|
|
what drugs are in Thiazolidinediones (TZD) class? |
- Pioglitazone (Actos) - Rosiglitazone (Avandia) |
|
|
What are CI in TZD? |
NYHA class III/IV heart failure |
|
|
What are warnings and side effect of TZD? |
-avoid pioglitazone in patients with active bladder cancer, bladder risk is increased with duration of use. - ADR: peripheral edema, weight gain, URTIs |
|
|
generic for Apidra? |
insulin glulisine |
|
|
Rapid acting insulin? |
- insulin aspart - insulin glulisine - insulin lispro (rapid as glu lisp) |
|
|
short acting insulin? |
Regular (Humulin R, Novolin R, Relion) shoRt are with R |
|
|
intermediate acting insulin? |
NPH (Humulin N, Novolin N, Relion)
iNtermediate are with N |
|
|
Long acting insulin? |
- insulin determine - insulin glargine - insulin degludec (long is with de-glar-deg) (take a long time to de-glare a degree) |
|
|
generic for Glucovance? |
metformine/glyburide |
|
|
generic for Victoza? |
Liraglutide (Victoria is a liar) |
|
|
Side effects of Byetta? |
- nausea - possible weight loss - pancreatic |
|
|
counseling for Byetta? |
- SC injection - if miss dose, omit it - inject within 60mins before AM and PM meals (do not inject after meal) - separate doses by 6 hours or more - ADR: nausea, wt loss, pancreatitis |
|
|
define severe hyperglycemia ? |
BG >= 300 or A1C >= 10 |
|
|
what are DKA symptoms? |
- BG >= 250 - ketone (urine, serum, fruity breath) - metabolic acidosis |
|
|
generic for Prandin? |
Repaglinide |
|
|
what is the estimated average glucose with the A1C of 7%? |
A1C of 7% = glucose 154 mg/dL |
|
|
Lorcaserin and Fluoroquinolones will cause increase or decrease of blood sugar??? |
they will lower the blood sugar |
|
|
generic for Amaryl? |
glimepiride |
|
|
generic for Januvia? |
Sitagliptin |
|
|
when does sodium bicarb is given? |
if pH<7 |
|
|
Exenatide is NOT safe in what condition? |
- CrCl < 30 ml/min - Acute pancreatitis - Gastroparesis |
|
|
Side effects of sitagliptin? |
- nasopharyngitis - URTI - pancreatitis - UTI - weight is neutral |
|
|
pioglitazone (Actos) a TZD is CI in what? |
CI in heart failure |
|
|
generic for Xigduo XR? |
dapagliflozin + metformin XR |
|
|
generic for Oseni? |
alogliptin + pioglitazone |
|
|
generic for Avandaryl? |
rosiglitazone + glimepiride |
|
|
can pramlintide cause weight gain? |
no |
|
|
side effects for SU (glipizide, glimepiride, glyburide)? |
- hypoglycemia - weight gain - nausea |
|
|
generic for Bydureon? |
exenatide XR |
|
|
generic for Glyset? |
- Miglitol |
|
|
what class of drugs cause pancreatitis? |
GLP-1 (-tide) - cause pancreatitis, wt loss DPP-4 inhibitor (-lip) , (alo-cause hepatotoxicity) |
|
|
treatment for DKA? |
- insulin - NS then 1/2NS - K replacement - if pH<7 then bi carb |
|
|
microvascular complications? |
- retinopathy - autonomic neuropathy - nephropathy |
|
|
what is insulin bolus dose? |
0.15 units/kg |
|
|
what is insulin infusion rate? |
0.1 units/kg/hr |
|
|
what insulin available at 200 units/ml? |
lispro and degludec |
|
|
x |
x |
