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74 Cards in this Set

  • Front
  • Back

What finger is on the midline of the hand?

Middle

What toe is on the midline of the foot?

2nd

What embryonic structure will become the neural groove?

The neural plate

What embryonic tissue does the central nervous system arise from?

Ectoderm (specifically neural ectoderm)

What embryonic tissue does the skin arise from?

The ectoderm

What is the protrustion from the neural tube canal that demarcates the alar plate and basal plate?

The sulcus limitans

What embryonic tissue do microglial cells arise from?

Mesenchyme

What components of the nervous system develop from the neural tube?

The brain and spinal cord

What components of the nervous system develop from the neural crest?

All neurons with cell bodies in the PNS

What type of CNS tissue do the alar plate and basal plate become?

Grey matter

What type of CNS tissue does the marginal layer become?

White matter

What are the stages of development of the neuron?

Neuroepithelium --> apolar neuroblast --> bipolar neuroblast --> unipolar neuroblast --> multipolar neuroblast

What are the stages of development of an astrocyte?

Neuroepithelium --> glioblast --> astroblast --> astrocyte (protoplasmic or fibrous)

What are the stages of development of an oligodendrocyte?

Neuroepithelium --> glioblast --> oligodendroblast --> oligodendrocyte

What tissue do the ependyma and choroid plexus epithelium arise from?

The neuroepithelium

What structure does the alar plate become?

The dorsal sensory horn of the spinal cord

What structure does the basal plate become?

The ventral motor horn of the spinal cord

Where do the cells that become melanocytes come from?

The neural crest

What structure enters the spinal cord to bring information to the dorsal sensory horn?

The dorsal sensory root

What structure leaves the spinal cord to bring information out from the ventral motor horn?

The ventral motor root

Which part of the nervous system uses a pre- and post-ganglionic nerve system?

Autonomic (sympathetic/parasympathetic) nervous system

How many nerves make up the path between the spinal cord and a skeletal muscle?

Just one - can be as long as needed.

What vertebral levels does the sympathetic chain align with?

T1 to L2/L3

Are post-ganglionic neurons myelinated?

No

What structures do post-ganglionic neurons align themselves with?

Blood vessels

What cells myelinate axons inside the CNS?

Oligodendrocytes

What cells myelinate axons in the PNS?

Schwann cells

What is the role of astrocytes in the CNS?

To line surfaces and support the blood-brain barrier

What is the role of microglial cells in the CNS?

They are phagocytic

What is the role of the tanycytes in the CNS?

Specialized ependymal cells; transmit hormones to the neurons from the ependyma

Ratio of Schwann cells to axons:

Multiple Schwann cells to one axon

Ratio of oligodendryocytes to axons:

Multiple axons myelinated by one oligodendrocyte

What junctions are found between the epithelial cells in the blood vessels in the CNS?

Tight junctions (to support the blood brain barrier)

How many cervical nerves do we have?

8

How many thoracic nerves do we have?

12

How many lumbar nerves do we have?

5

How many sacral nerves do we have?

5

How many cervical vertebrae do we have?

7

Where do the cervical nerves arise in relationship to their same-numbered vertebrae?

Above them, except for cervical nerve 8 (above T1)

Where do the thoracic, lumbar, and sacral nerves arise in relationship to their same-numbered vertebrae?

Below them

At what level does the spinal cord proper end?

Around T1-T2

What singular spinal nerve is located below the sacral nerves?

Coccygeal

What is the name for the tapered end of the spinal cord?

Conus medullaris

What is the name for the extension of the dura/pia mater that anchors the spinal cord to the coccyx?

Filum terminale ("ending thread")

What is the name for the collection of nerves travelling past the end of the spinal cord down to their emergence points?

Cauda equina ("horse's tail")

What level does the filum terminale begin?

Around S1

What is the outermost layer of the meninges?

Dura mater ("tough mother")

What is the innermost layer of the meninges?

Pia mater ("pious/tender mother")

What is the middle layer of the meninges?

Arachnoid mater ("spider mother" referring to spiderweb-like appearance)

What is the difference between the dura mater around the brain and the dura mater around the spinal cord?

Near the brain, the dura mater is adhered to the skull; near the spinal cord, the dura mater is surrounded with a layer of fat but is not adhered to any structure

What structure do spinal nerve rootlets aggregate to become?

Spinal nerve roots

What two roots does every spinal nerve have?

Anterior (ventral) and posterior (dorsal) roots

What do the ventral and dorsal spinal roots merge to become?

A mixed spinal nerve

How long is the mixed spinal nerve segment?

Very short; 3-5mm

What does the mixed spinal nerve segment divide into?

Dorsal/posterior primary ramus


Ventral/anterior primary ramus

Do the rami carry motor, sensory, or both nerve fibers?

All rami + branches carry both

What is the common name for CN I?

Olfactory nerve

What is the common name for CN II?

Optic nerve

What is the common name for CN III?

Oculomotor nerve

What is the common name for CN IV?

Trochlear nerve

What is the common name for CN V?

Trigeminal nerve

What is the common name for CN VI?

Abducens nerve

What is the common name for CN VII?

Facial nerve

What is the common name for CN VIII?

Vestibulocochlear nerve

What is the common name for CN IX?

Glossopharyngeal nerve

What is the common name for CN X?

Vagus nerve

What is the common name for CN XI?

Accessory nerve

What is the common name for CN XII?

Hypoglossal nerve

What two components make up the accessory nerve (CN XI)?

Cranial component


Spinal component

What muscles does the spinal component of the accessory nerve innervate?

Trapezius and sternocleidomastoid

What path does the cranial component of the accessory nerve take?

It joins with the vagus nerve very shortly after it arises

How many pairs of spinal nerves are there?

31

How many pairs of cranial nerves are there?

12

What structure do the spinal nerves enter/exit the vertebral column through?

The intervertebral foramina