Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
22 Cards in this Set
- Front
- Back
|
Anticoagulents (Rx names)
|
Heparin
Warfarin |
|
|
Antiplatelet (Rx names)
|
aspirin
|
|
|
Thrombolytic (Rx names)
|
streptokinase
|
|
|
Heparin (unfractionated) - Adverse Effects
|
-Hemorrhage
-Heparin-induced thrombocytopenia -Hypersensitivity reactions -Injection site irritation -Long term, high dose use: osteoporosis |
|
|
Low-Molecular-Weight Heparins - Adverse Effects
|
-Bleeding
-Immune-mediated thrombocytopenia -Neurologic injury -Cost |
|
|
Fondaparinux [Arixtra®] - Adverse Effects
|
-Bleeding
-Patients weighting less than 50 kg -Thrombocytopenia -Spinal or epidural hematoma |
|
|
Direct Thrombin Inhibitors (Bivalirudin [Angiomax®]) - Adverse Effects
|
-Back pain
-Nausea -Headache -Bleeding |
|
|
Warfarin - Adverse Effects
|
-Hemorrhage
-Fetal hemorrhage and teratogenesis from use during pregnancy -Use during lactation |
|
|
Three types of Antiplatelet Rx
|
-GP IIb/IIIa receptor antagonists
-Aspirin -ADP receptor antagonists |
|
|
Adenosine Diphosphate Receptor Antagonists (2)
|
-Ticlopidine [Ticlid®]
-Clopidogrel [Plavix®] |
|
|
Glycoprotein (GP) IIb/IIIa receptor antagonists
|
-Tirofiban (Aggrastat®)
-Eptifibatide (Integrilin®) -Abciximab (Reopro®) |
|
|
Thrombolytics (5)
|
-Streptokinase (Streptase®)
-Urokinase (Abbokinase®) -Reteplase (Retavase®) -Alteplase (Activase, Cathflo Activase) -Tenecteplase (TNKase®) |
|
|
Streptokinase (Streptase®) - Adverse Effects
|
-Bleeding
-Antibody production -Hypotension -Fever |
|
|
Hematopoiesis (def)
|
Process by which blood cells and platelets are produced
|
|
|
Hematopoietic growth factors
(2 Types) |
Hematopoietic growth factor
-Erythropoietin (RBCs) -Leukopoietic (WBCs) Thrombopoietic growth factor -Oprelvekin (platelets) |
|
|
Applications of Hematopoietic Growth Factors (3)
|
-Acceleration of neutrophil and platelet repopulation after cancer chemotherapy
-Acceleration of bone marrow recovery after an autologous bone marrow transplant (BMT) -Stimulation of erythrocyte production in patients with chronic renal failure (CRF) |
|
|
Erythropoietic Growth Factorsm(2)
|
-Epoietin Alfa, erythropoietin
-Darbopoeitin, eythropoietin |
|
|
Erythropoietic Growth Factors - Adverse Effects
|
-Hypertension
-Cardiovascular events -Autoimmune pure red-cell aplasia |
|
|
Leukopoietic Growth Factors (2)
|
-Filgrastim, granulocyte colony-stimulating factor (G-CSF), (Neupogen®)
-Sargramostim, granulocyte-macrophage colony-stimulating factor (GM-CSF), (Leukine®) |
|
|
Filgrastim, granulocyte colony-stimulating factor (G-CSF), (Neupogen®) - Adverse Effects
|
Bone pain, Leukocytosis
|
|
|
Sargramostim, granulocyte-macrophage colony-stimulating factor (GM-CSF), (Leukine®) - Adverse Effects
|
-Leukocytosis
-Thrombocytosis |
|
|
Thrombopoietic Growth Factor (Oprelvekin, Interleukin-11, (Neumega®)) - Adveres Effects
|
Fluid retention
Cardiac dysrhythmias Effect on the eye |
