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16 Cards in this Set

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  • Back

Benzodiazepines/anxiolytic mechanism of action

CNS depression by inhibiting GABA

Are benzodiazines safe the give for longer than 14 days?

Yes, it is the ONLY sedative safe for use >14 days.

Do benzodiazepines suppress REM?

No.

Flumazenil

Antidote for benzodiazepine OD

Benzodiazepines major side effects

Drowsiness, hypotension, slurred speech, memory impairment, hangover effect, resp depression, CNS excitemend, vivid nightmares.

Benzodiazepine contraindications

Glaucoma, BPH.


Give low dose to elderly.

Barbituate actions

CNS depressant

Long acting barbituate drug

phenobarbital/Luminal

Intermediate acting barbituate drug

Amytal/amobarbital

Short acting barbituate drug

pentobarbital/Nembutal

Ultra short acting barbituate drug

thiopental sodium/Sodium Penothal "truth serum"

Barbituate major side effects

Excessive CNS depression, Rebound insomnia, CNS excitement, anxiety, resp depression, toxicity and chronic poisoning.

Luminal/phenobarbital Use

Treat primary seizure disorder

Amytal/amobarbital use

Sleep sustainer, preanesthesia sedation

pentobarbital use

Sleep inducer, preanesthetic sedation

thiopental sodium/Sodium Penothal use

Anesthetic induction agent.