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4 Cards in this Set
- Front
- Back
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What is myeloma?
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Malignant proliferation of plasma cells which produce identical immunoglobulins (Igs) which are dyscfunctional (lack a heavy chain - Bence Jones protein)
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Symptoms? 5
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Hypercalcaemia: stones, bones, abdominal groans
Osteolysis: Fractures Anaemia Infections Renal impairment |
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Tests:4
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FBC
U+Es X-Ray - fractures and lysis Serum and urine electrophoresis looking for paraprotein (Bence-Jones protein) |
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Rx: (6)
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NSAID's pain
Bisphosphonates - fractures Fluids - renal impairment Transfusion - anaemia Antibiotics - infection Chemo |
