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67 Cards in this Set

  • Front
  • Back
Psych techniques
- psychoanalysis
- behavior therapy
- cognitive therapy
- supportive
- neutral role, clarifying, confronting, interpret, dreams
- teach relaxation techniques and recondition
- identify negative thoughts to alter connection to mood
- warm, empathetic, reliable support s.a. acute crisis, chronic psych
Hypercortisol causes and responses to doses of dexamethasone
ACTH dependent (high)
- pituitary or ectopic
Next: dexamethasone
- HD suppresses pituit
but not ectopic
ACTH independent (low)
- adrenal

Cushings (ACTH pituitary)
Hypercortisol treatments
Cushings - 1st) transsphenoidal microadenectomy, 2nd) pituitary radiation

Adrenal options: metyrapone (block secret) or adrenalectomy ... later line: mitotane
Multifocal atrial tachycardia def'n and associated disorders
HR>100 w/3+ p-wave morphologies

COPD, IHD, glucose intolerance, hypokal, hypomag
Acute right heart/ventric failure in inferior wall MI tx
Preload dependent >> IVF

Avoid: nitro and diuretics (which decr preload)
Valproate and phenytoin interaction
relative contraindication to drug combination: shared plasma binding >> phenytoin levels rise (monitor or choose other agent)
ARDS diagnosis criteria
1) acute
2) bilateral patchy
3) wedge pressure <18 or no clinical LV dysfcn
4) P(aO2):FiO2<200
Completely dilated (second stage) + multiple late fetal decels
fetal distress (UP insuff)

Next: reposition LLD (open IVC), stop oxytocin (incr ut perfusion), O2

C-sect if loses variability, no change for 2-3 hours in cervical exam

Forceps or vacuum if full dilated, fetus greater than 2+, anesthetized, no CPD
Criteria for referal to burn center
2nd degree >20% adult or >10% if <10yo or >50yo

3rd degree >5% any age

inhalation injury, suspected abuse, significant face or genitals or joints, associated injuries (s.a. fx)
Catatonic schizophrenia characteristics:
2+ excessive motor activity, immobility, extreme negativism, mute, waxy flexibility, echolalia, echopraxia
hypercalcemia sx, tx
bones
-pain/fx w malig/lytic
stones
-calcium kidney stones
groans
-PUD, pancreatitis
psych overtones
-fatigue, depression, irritable, sleep disturbance

ECG - short QTc

Acute tx: IVF, loop diuretic (furosemide)
child - painless GIB
#1 meckel's diverticulum <2yo (and in 2%)
Childhood bone findings:
-Osteoid osteoma


-Bone cyst

-Enchondroma

-Ewing's sarcoma

-Osteosarcoma
-night pain, aspirin helps, lucency + surrounding sclerosis, ~leg, haphazard trabeculae
-leg, eccentric lysis, thinning cortex
-hands, diaph lysis, thinning cortex, typ asx
-prox long bones, lysis, onion skinning, periost rxn, F, WBC, ESR
-10-20yo M, metaph, "Codman triangle" periost rxn
Nonreassuring fetal tracings
tachy >160 bpm
prolonged brady <100 bpm
lost beat-beat variability
variable decels >1min
Developmental hip dysplasia tx
<6mo: Pavlik harness (flex, abduct)
6-15mo: closed reduction + spica cast
15-24mo: open reduction if closed failed
Thyroid cancers (detail)
#1 Papillary ~70%
Hyperthyroid, F>M

#2 Follicular ~20%
Hyperthyroid

#3 Medullary ~7%
Calcitonin, MEN IIA/B
Risks associated with acromegaly
Colon polyps/cancer, CAD, HTN, DM, sleep apnea
Biopsy findings dermatomyositis vs polymyositis
DM - perivasc and perimysial inflammation

PM - endomysial inflammation
Hereditary GI polyp disorders
Peutz-Jeghers
-hamartomatous polyps
-abnl ser-threo kinase

Lynch = HNPCC
-if get polyp, rapid transformation

Bloom
-UV and rad sensitive

Turcot's (APC or HNPCC gene)
APC: cafe au lait, childhood medulloblastoma

Gardner's
APC, polyps, osteomas, skin/soft tissue tumors
Facial skin tumors: keratoacanthoma vs squamous cell carcinoma vs
basal cell carcinoma
-rapid grow (d-w), central depression, ~disappear spontaneously; mimic SCC but grow faster

-#2 skin cancer, verrucous, nodular, ulcerated, esp s/p burn or actinic keratosis

#1 skin tumor, nodular most common (waxy nodule, vessels around it), central crater -> ulcer (ex: on ear)
FDA approved alzheimer's medications
Cholinesterase inhibitors for mild-moderate disease

Donepezil (least fx)
Rivastigmine
Galantamine
Tacrine
Nephrogenic DI, Central DI, and SIADH treatments
Water Restriction

Desmopressin (DDAVP)
- fx: incr vWF w/indirect incr in FVIII
Thiazides

Demeclocycline
- fx: nephro DI
Child motor development
3mo sit w/support

7mo sit alone (rounded back) and pull to stand

10mo cruising, sit w/back straight

12mo walk holding hand
Child vocal development
3mo "ahh" single sylable

7mo babble

10mo "mama"
Child hand skills
10mo - wave bye bye
Mycoses risk factors
Cryptococcus
- soil, pigeon droppings

Blastomycosis
- Central US
- violaceous skin lesions

Histoplasmosis
- Mississippi river valey
- skin, GI, CNS, adrenals
- spelunking, bird/bat guano

Coccidiomycosis
- SW US
- erythema multiforme or nodosum, bones, CNS
Aldosterone functions and syndromes
Mineralocorticoid resorb Na, excrete K

Excess (hypokal) - Conn's

Deficient - Addison
Congenital: 21 hydroxylase def
Triple screen and birth findings
- Trisomy 13
- Trisomy 18
- Trisomy 21
aFP, estradiol, bhcg

Patau (die wks-mos)
- sm head, polydactyly, small head, vision, cleft, celes (spine, stomach), rocker feet

Edwards (#2)
- all decr
- hypotonia later hypertonia, horseshoe kidney, flexed overlap fingers, GI malrotation

Down's (#1)
- decr aFP, estradiol
- incr bhcg

High afp w/NTDs, GI cele, multis
Tx breast-feeding mastitis
Diclox 10-14d

Alt if allergic: Azithro
IgA nephropathy
young adult male, s/p URI, nephritic

IgA deposits + normal C3

Tx: glucocorticoids
ACEi if Uprot too
Treatment of childhood neuro disorders:

Spastic CP

West Syndrome

Tics
Baclophen, diazepam, dantrolene (relaxants)

ACTH and clonazepam

Pimozide
Childhood rash: trunk outwards
HHV-6 (roseola, 6th dz)
s/p URI, typ high fever
Childhood rash: head/face then down
Measles
- fades head down, desquamates, brown discoloration

Rubella
- tender, fades rapidly as redness spreads

Parvovirus B12 (erythema infectiosum, 5th disease)
-slapped cheeks, LGF, trunk and prox extrem
Tuberous sclerosis

von Hippel-Lindau

Sturge-Weber
MR, sz (cortical tubers), leathery patches, ash leaf sponts, growths (ungal, retinal hamart, cardiac, astrocyte, renal angio)

CNS hemangioblastomas, retinal angioma, misc tumors

angiomas: facial (port-wine), leptomening, choroidal
Acute adrenal crisis (and name in meningococcemia)
Hydrocortisone and IVF before labs return

Waterhouse-Friderichsen typ 2/2 adrenal hemorrhage
Triple screen and birth findings
- Trisomy 13
- Trisomy 18
- Trisomy 21
aFP, estradiol, bhcg

Patau (die wks-mos)
- sm head, polydactyly, small head, vision, cleft, celes (spine, stomach), rocker feet

Edwards (#2)
- all decr
- hypotonia later hypertonia, horseshoe kidney, flexed overlap fingers, GI malrotation

Down's (#1)
- decr aFP, estradiol
- incr bhcg

High afp w/NTDs, GI cele, multis
Tx breast-feeding mastitis
Diclox 10-14d

Alt if allergic: Azithro
IgA nephropathy
young adult male, s/p URI, nephritic

IgA deposits + normal C3

Tx: glucocorticoids
ACEi if Uprot too
Treatment of childhood neuro disorders:

Spastic CP

West Syndrome

Tics
Baclophen, diazepam, dantrolene (relaxants)

ACTH and clonazepam

Pimozide
Childhood rash: trunk outwards
HHV-6 (roseola, 6th dz)
s/p URI, typ high fever
Childhood rash: head/face then down
Measles
- fades head down, desquamates, brown discoloration

Rubella
- tender, fades rapidly as redness spreads

Parvovirus B12 (erythema infectiosum, 5th disease)
-slapped cheeks, LGF, trunk and prox extrem
Tuberous sclerosis

von Hippel-Lindau

Sturge-Weber
MR, sz (cortical tubers), leathery patches, ash leaf sponts, growths (ungal, retinal hamart, cardiac, astrocyte, renal angio)

CNS hemangioblastomas, retinal angioma, misc tumors

angiomas: facial (port-wine), leptomening, choroidal
Acute adrenal crisis (and name in meningococcemia)
Hydrocortisone and IVF before labs return

Waterhouse-Friderichsen typ 2/2 adrenal hemorrhage
Adenocarcinoma of the lung manifestations
clubbing, thrombophleb, nonbacterial verrucous endocarditis

Subtype: bronchoalveolar w/multiple nodules, interstitial infiltrate, lots sputum
Kawasaki's dz criteria
F 5+ days

Four of the five:
- b/l conjunctivitis
- lip/oral lesions
- extremity red/edema
- rash
- cervical LN
Ranson's criteria (severity of acute pancreatitis)
On admission:
- >55yo
- WBC>16K
- LDH >350
- AST >250
- Gluc >200

48hrs
- HCT decr 10%
- BUN incr 5 w/adeq IVF
- Ca <8
- PO2 <60
- BD >4
- fluid seq >6L

Note: good HR and BP indicate fluid status
Multiple myeloma serum marker for tumor mass and response to treatment
B2-microglobulin
Trace metal deficiencies:
- diarrhea, dermatitis, alopecia (w/o alopecia)

- glucose intolerance, lipid changes

-anemia, neutropenia

- cardiomyopathy, sk muscle dysfcn
- Zinc, esp w/TPN (niacin, no assn w/TPN)

-Chromium

-Copper, esp w/TPN free AAs

- Selenium
Tick borne diseases
Ehrlichia
- Ixodes tick
- neuro sx (esp confusion)
- intraneutrophil
- doxycycline

Lyme (borrelia)
- Ixodes tick
- rash, migratory arthritis
- doxycycline (alt: azithro)

Babesiosis
- protozoa carried by several ticks (Ixodes, deer, etc)
- intraerythrocytic
- quinine + clinda
Primary biliary cirrhosis
F>>>M

Esp assn w/RA and Sjogrens

Antimitochondrial ab
Primary sclerosing cholangitis
M>F

Esp assn w/UC

pANCA
low phos, Ugluc, acidosis
RTA II - Fanconi syndrome
11B-hydroxylase def

17a-hydroxylase def

21-hydroxylase def
#2 cause congen adrenal Hplasia- disting bc HTN + decr K (no cortisol)

w/def 17,20-lyase, delayed puberty HTN, hkal, hgonad (no cortisol or androgens or estroen)

#1 cause congenital CAH typ w/hTN, hNa, HK, MAcid (low cortisol and aldosterone)
Ejection murmur bt apex and LLSB, cresc-decr, non-radiating
Hypertrophic cardiomyopathy

tx: b-blockers, CCB
Schizophrenia subtypes
Paranoid
- #1, prominent bizarre delusions, auditory hall

Catatonic
- immobility w/periods of extreme excitement

Disorganized
- poor px, prevents functioning in society

Residual
- if had a different type and loses positive sx

vs. Schizotypal PD
- odd, eccentric, not severely psychotic perceptions, withdrawn, typ still a few friends
EEG 3Hz spike and wave
Absence sz - often regress during puberty

tx w/ethosuxi mide (a CCB)
First childhood seizure
Febrile (>100.4) 6mo-6yo - decr temperature

Absence with char EEG (3Hz spike and wave) - ethosuximide

Nonfebrile w/EEG changes - option to treat (phenobarb for complex partial)
Aphasias:
- Broca
- Conduction
- Wernicke
- Transcortical sensory
- Global
- production problem; comprehension preserved (sup div MCA, inferior post frontal)
- problems repeating only (arcuate fasciculus)
- problems w/comprehension, output paraphasic, circumloc (post 1/3 sup temp gyrus)
- (near Wernicke's)
- (large L hemi)
Adult PCKD diagnostic criteria
2+ cysts if <30yo
2+ each side <60yo
4+ each side 60+
Diabetes screening criteria
>45yo BMI 25+

<45yo BMI 25+ w/RF

Fasting Glucose, if 100-126, rpt, if still impaired do 2hr GTT and fasting insulin
Thrombolytic contraindications
- Stroke or head trauma w/in 3mo
- Recent MI
- prior ICH
- major surgery w/in 2wks
- GI/GU bleed w/in 3wks
- seizures at stroke onsest
Lichen planus vs lichen sclerosis
atrophic, flat purple papules on inner labia

postmen, atrophic thin white labia, shrink/agglut of minoras
NF 1

NF 2

TS
cafe au lait, fold Hpigment, iris hamart (lisch nodule), optic glioma

acoustic neuromas (deaf ~20yo)

hamartomas (facial, ungal, retinal, cortical, subependymal), ash leaf, leathery neck, MR, autism, giant cell astrocytoma, kidney angiomyolipoma, renal cysts, lungs, heart rhabdomyoma (also cafe au lait)
Esophageal varices management
prevent bleed: Bblock

acute bleed: somatostatin tx or analog + endoscopic ligation or sclerotherapy

refractory or recurrent: balloon tamponade or PS shunt
tx pyelonephritis
10d cipro (but not moxi which does not concentrate in urine as well)
Pneumonia treatments
- CAP

- Atypical

- HAP
- empiric CAP (macrolides: erythro, clarithro)
- CAP Pneumococcus (rapid devel, consol, quellung: ampicillin or ceftriaxone if PCN-res)

- erythro, azithro, (alt: doxy)

- Aztreonam (monobactam, GN)
OCD vs OCD PD
more severe w/ritualized behavior impairing their life, distresed by behavior, ~anxiety disorder (>> CBT + SSRI)

preoccupation with details, rules, org, no sense of conflict