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27 Cards in this Set

  • Front
  • Back
have a high proportion of positively charged amino acids that bind tightly to negatively charged DNA
the basic beadlike form of DNA packaging
highly compacted chromatin that is visible with a light mircoscope during interphase
the more open, unraveled form of eukaryotic chromatin
nucleotide sequences that are present in many copies in a genome, usually not within genes
repetitive DNA
isolation of repetitive DNA in a centrifuge tube
satellite DNA
interspersed repetitive DNA which are about 300 nucleotide pairs long
Alu elements
a collection of identical or very similar genes
multigene family
similar to real genes, but do not yield functional products
selective synthesis of DNA, results in multiple copies of a single gene, thereby enhancing expression
gene amplification
transposable elements that move within a genome by means of an RNA intermediate
proteins that specifically recognize and help combat viruses, bacteria, and other invaders of the body
the divergence in form and function as cells become specialized during an organism's development
cellular differentiation
the attachment of methyl groups to DNA bases after DNA is synthesized
DNA methylation
where methylation permanently turns off either the maternal or paternal allele of certain genes
genomic imprinting
attachment of acetyl groups to certain amino acids of histone proteins
histone acetylation
segements of non-coding DNA that help regulate transcription of a gene by binding proteins
control elements
recognizes transcription factors that can stimulate transcription of nearby genes
transcription factor that binds to an enhancer and stimulates trcascription of a gene
a part of its 3-dimensional structure that binds to DNA
DNA-binding domain
different RNA molecules are produced from the same primary transcript, depending on which are introns and exons
alternative RNA splicing
protein complex that recognizes and destroys proteins tagged for elimination by the small protein ubiquitin
invovled in triggering cancerous characteristics
gene with potential to cause cancer but that requires alteration to become an oncogene
gene whose protein products inhibit cell division, thereby preventing uncontrolled cell growth
tumor-suppressor genes
codes for Ras protein, results in stimulation of the cell cycle
ras gene
expressed when a cell's DNA is damaged; "the guardian angle of the genome"
p53 gene