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34 Cards in this Set

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osteitis fibrosa cystica
cystic bone spaces filled with brown fibrous tissue (bone pain ) from secondary PTH elevations from hypovitaminosis D (usually renal failure)

"subperiosteal thinning + cystic lesions"

Mostly affects the cortical bone.
fracture of dislocation of humerus
axillary n
motor: arm abduction

sensory: over deltoid muscle
midshaft fracture of humerus
radial n
motor: BEST extensors

sensory: posterior arm, posterior 1st-3rd digit
supracondylar fracture of the humerus
median n
Sensory: 1st - 3rd digits anterior (palm-side)

Motor deficits: wrist flexion

can't opposition of thumb "Ape hand"
compressed by carpal tunnel syndrome and by dislocated lunate (distal lesion)
median n
sensory: 1st - 3rd digits anterior (palm-side)

motor: "Median claw"
2nd and 3rd fingers are clawed (can't extend them) also can't really flex @ MCP
lesioned by trauma to heel of the hand; fracture of hook of hamate (distal lesion)
ulnar n
4th and 5th finger both sides

pope's blessing: loss of median lumbricals- extension of DIP, PIP on 4th and 5th
fracture of medial epicondyle of humerus (proximal lesion)
ulnar n
sensory: 4th and 5th finger both sides

medial finger flexion, wrist flexion (radial deviation of wrist upon flxion)
4 symptoms of thoracic outlet syndrome:
1. atrophy of thenar + hypothenar eminences (median + ulnar are affectected)
2. atrophy of interosseus muscles (ulnar n --> adduction and abduction of fingers)
3. sensory defect on medial side of forearm and hand
4. dissappearance of radial pulse upon moving the head toward the ipsilateral side
trauma to lateral aspect of leg at knee
common peroneal n

cannot evert, dorsiflex - foot drop
sensory = dorsal aspect of foot
posterior popliteal fossa trauma
tibial n

cannot invert, plantarflex foot
sensory = sole of foot
anterior hip dislocation
obturator n

thigh adduction
medial thigh sensory
pelvic fracture
femoral n

thigh flexion and leg extension
anterior thigh and medial leg
anti-Scl-70 antibody (anti-DNA topoisomerase I antibody)
diffuse scleroderma

widespread deposition of fibrosis and collagen in skin and visceral (kidney, heart, lungs)
anticentromere antibody
CREST syndrome

limited skin involvement - often confined to skin and face.
more benign clinical course.
common peroneal a. wraps around what bone?
common peroneal a. wraps around the lateral aspeect of the fibula
symmetric proximal muscle weakness by CD8+ injury to myofibers
polymyositis
malar rash (similar to SLE)
heliotrope rash (shawl and face rash)
gottron's papules - purple papules on knuckles
increased risk of malignancy

what would be the 4 lab findings
elevated CK, aldolase, positive ANA, anti-Jo-1

*these would also be the findings for polymyositis (symmetric proximal muscle weakness by CD8+ injury to myofibers)
anti-dna topoisomerase I antibody
diffuse scleroderma - widespread skin involvement, rapid progression, early visceral involvement (kidney, heart, lungs)
anti-centromere antibody
crest syndrome
calcinosis
reynaud's
esophageal dysmotility
sclerodactyly
telangiectasia

*limited skin involvement , often confined to fingers and face

more benign than diffuse scleroderma
rhomboid crystals that are weakly positively birefringent in knee

what color when parallel, perpendicular
pseudogout - calcium pyrophosphate crystals
no treatment

parallel = blue
perpendicular = yellow
where is giant cell tumor located
epiphysis of long b ones

-double bubble appearance on x-ray, spindle shaped cells with multinucleated giant cells
morphology of osteoid osteoma
woven bone surrounded by osteoblasts

found in proximal tibia/femur (Knee)
mature bone with cartilaginous cap in men < 25 yrs

dx? where is it located?
osteochondroma

found in metaphysis
benign cartilaginous neoplasm in INTRAMEDULLARY bone. usually in distal extremities
endochondroma
most common tumor- often has Codman's triangle or sunburst pattern from elevation of periosteum on x-ray
osteosarcoma

poor prognosis

found in metaphysis of long bone often in the knee
onion skin appearance in bone in DIAPHYSIS
Ewing's sarcoma

eWINGS and onion RINGS

11;22 translocation
chondrosarcoma is located where?
expansile glistening mass within the medullary cavity.
3 parts of a bone
diaphysis (middle), metaphysis, epiphysis
antibodies in sjogrens syndrome
SS-A (Ro) and SS-B (La) antibodies to ribonucleoprotein

1. dry eyes
2. dry mouth
3. arthritis
*parotid enlargement --> possible risk of B-cell lymphoma

Sicca syndrome has no arthritis but all that dryness.
gout has what birefringent? what color are crystals under parallel light?
negative bifringement
yellow when parallel
3 things you see with infecrious arthritis caused by s. aureus, strep pneumoniae, gonorrhea
1. synovitis (knee)
2. tenosynovitis (hand)
3. dermatitis (pustules)
triad in ankylosing spondylitis
stiff spine from inflammation that causes fusion
uveitis
AORTIC REGURG*
SLE test:
_____ is sensitive but not specific (screening)
_____ very specific, poor prognosis
_____ specific but not prognostic
_____ drug induced lupus
SLE test:
anti nuclear antibody = sensitive but not specific (screening)
anti-dsDNA = very specific, poor prognosis
anti-smith antibodies = specific but not prognostic
antihistone antibodies = drug induced lupus
neuromuscular jxn disease with hyporeflexia and areflexia + autonomic symptoms (dry mouth, impotence)
Lambert eaton syndrome