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17 Cards in this Set

  • Front
  • Back

What are muscles?

- specialised tissue largely made of protein


- good blood supply


- mammals=40% body weight


- responds to nervous system and chemical stimulation

What are the types of muscles?

- striated


- smooth


- cardiac

What are striated muscles?

- muscles attached to skeleton


- striped under microscope


- locomotion/rapid contraction


- fatigues quickly

What are smooth muscles?

- Gut/blood vessels


- not striped


- move food through gut/involuntary control/slow contraction


- fatigues

What are cardiac muscles?

- heart


- striped


- contracts spontaneously


- doesn't fatigue

What would happen if muscles were made of individual cells?

- won't contract efficiently


- junction between adjacent cells weak=reduce overall strength

What is the structure of a muscle fibre?

- made of myofibrils parallel to each other


- each made of several sarcomeres


- cytoplasm of myofibrils=sarcoplasm (mainly mitochondria


- membrane network (sarcoplasmic reticulum) stores/releases Ca2+

What are the components of a sarcomere?

- I band


- A band


- Z lines


- H zone

What is the I band of a sarcomere?

- the gap between the end of the myosin filaments from neighbouring sarcomeres

What is the A band of a sarcomere?

- the length of the myosin filaments

What are the Z lines of a sarcomere?

- the join of actin filaments which defines the sarcomere

What is the H zone of a sarcomere?

- The gap between myosin heads where there's just filament

Label the parts of this striated muscle.

Label the parts of this striated muscle.

1. sarcomere


2. H zone


3. thin actin filament


4. thick myosin filament


5. Z line


6. A band


7. I band

What is a neuromuscular junction?

- point where motor neurone meets skeletal fibre (many along muscle)


- one junction=long for contraction travel across muscle


- not all fibres contract simultaneously=slow movement

How does transmission across a neuromuscular junction work?

- nerve impulse reaches neuromuscular junction


- synaptic vesicles fuse with presyn=release ACh


- diffuses to postsyn=change permeability to Na+ ions=enter/depolarise


- broken down by acetylcholinesterase=muscle not overstimulated


- choline/acetyl diffuse back into neurone=recombines

What are the similarities between a neuromuscular junction and a synapse?

- neurotransmitters transported by diffusion


- receptors on binding with NT=influx Na+


- Na+/K+ pump=repolarise axon


- enzyme breakdown NT

What are the differences between a neuromuscular junction and a synapse?

- only excitatory


- only links neurones to muscles


- only motor neurones involved


- AP ends here


- ACh binds to receptors on muscle fibre membrane