Muscle Tissue

Front 1

Muscle tissue is composed of cells that_________

Back 1

Optimize the universal cell property of contractility

Front 2

Microfilaments of actin enable______

Back 2

Cells to change shape and move

Front 3

Intermediate filaments________

Back 3

Reinforce the cell and anchor certain organelles

Front 4

Microtubules does 3 things, what are they?

Back 4

1. Give the cell rigidity

2. Provide anchors for organnelles

3. Act as tracks for organelle movement

Front 5

Prominent location of Smooth muscles include?

Back 5

1. Walls of GI tract

2. Walls of arteries and veins

3. Around glands

Front 6

Smooth muscle features :

Back 6

1. Slow, sustained contractions

2. Under autonomous (non-voluntary) control.

3. Contain actin and myosin filaments but lack sacomeres

4. Centrally located enlogated nucleus

Front 7

The repetitive functional subunit of the contractile apparatus the sacomere, extends from ________

Back 7

Z disc to Z disc and is about 2.5um long in resting muscle.

Front 8

H band is a :

Back 8

Lighter region on either side of the M line, which contains only thick filaments.

Front 9

Z line consists of proteins called _______ which interconnect __________ of the adjacent sacomeres.

Back 9

Actinins, thin filaments

Front 10

I band contains ________

Back 10

Thin filaments but not thick filaments

Front 11

Troponin binds tropomyosin to actin, it consists of three subunits:

Back 11

1. TnL : binds to actin

2. TnT : bonds to tropomyosin

3. TnC : binds calcium

- controlled by Ca2+

Front 12

The capillaries that penetrate the muscle are of the _________ type. A. Continuous B. Discontinuous

Back 12

Continuous

Front 13

The sarcoplasm is filled with long cylindrical filamentous bundles called_________

Back 13

Myofibrils

Front 14

The major protein of the M line is

Back 14

Creatine kinase

Front 15

Striated muscle filaments contain several protiens; the four main proteins are :

Back 15

-actin

-tropomyosin

-troponin

-myosin

Front 16

Thin filaments are composed of_______, _______and _______.

Back 16

Actin, tropomyosin and troponin

Front 17

T-tubule (transverse tubule) is a deep invagination of the sarcolemma (plasma memberane), only found in ______ and ________ muscle cells.

Back 17

Skeletal and Cardiac muscle cells

Front 18

In skeletal muscle cells, T-tubule invaginations are typically located at the junction overlap between ___ and ___ bands of the sacomere.

Back 18

A and I bands

Front 19

Cardiac has dyad which is composed of a T-tubule and a single terminal cisterna, and it occurs at the ___ line.

Back 19

Z line

Front 20

Skeletal muscle fibres are highly differentiated cells which are unable to undergo cell division. True/False

Back 20

True

Front 21

In adults, there are few remaining stem cells closely associated with muscle fibres which are referred to as _____

Back 21

Satellite cells

Front 22

Skeletal muscle cells are multinucleated. True/false

Back 22

True

Front 23

If the axons to a myofiber fail to develop, or are damaged the muscle cells will wither in the process known as

Back 23

Neurogenic atrophy

Front 24

What Is myasthenia gravis?

Back 24

Myasthenia gravis is an autoimmune disorder characterized by progressive muscular weakness caused by a reduction in the number of functionally active acetylcholine receptors in the sarcolemma of the myoneural junction.

This reduction is caused by circulating antibodies that bind to the acetylcholine receptors in the junctional folds and inhibit normal nerve muscle communication.

Front 25

Skeletal Muscle Longitudinal section features :

Back 25

- Peripheral Nuclei

- Striation

- No Branching

Front 26

Skeletal Muscle Longitudinal Section :

Back 26

- Peripheral Nuclei

- Massive Cytoplasm

Front 27

Smooth muscle fibres interlace to form sheets or layers rather than bundles. True/False

Back 27

True

Front 28

Smooth muscle have myofibrils and sacomere. True/False

Back 28

False

Front 29

Smooth muscle have actin and myosin. True/False

Back 29

True

Front 30

Gap junction link cells electrically. True/False

Back 30

True

Front 31

Smooth muscle cells are unable to undergo cell division. True/False

Back 31

False

Front 32

Smooth muscle cells cannot regenerate after damage. True/False

Back 32

False

Front 33

The intermediate filaments of Smooth muscle is known as _____

Back 33

Desmin

Front 34

_________ cells play a prominent role in wound healing where they proliferate and secrete collagen producing a fibrous scar.

Back 34

Myofibroblast

Front 35

___________ have processes which surround secretory portions of many exocrine glands.

Back 35

Myoepithelial cells

Contraction of these cells propels secretory product into the duct system.

Front 36

Smooth Muscle Longitudinal Section features :

Back 36

-Central Nuclei

-Meshwork apperance

-No Striations

Front 37

Smooth Muscle Cross Section features :

Back 37

- Central Nuclei

-low cytoplasm : Nucleus Ratio

Front 38

Cardiac myocytes are linked together end to end by special anchoring junctions called ________

Back 38

Intercalated discs

Front 39

Intercalated discs contain _______, ________ and ________ allowing passage of electrical excitation between cells and synchronous muscle contraction.

Back 39

Adherent junctions, desmosomes and gap junctions

Front 40

The T-tubule are more numerous and larger in skeletal muscle than in ventriclular muscle. True/False

Back 40

False

Front 41

Cardiac Muscle Longitudinal Section features :

Back 41

-Central Nuclei

-Striation

-Branching

-Intercalated Discs

Front 42

Cardiac Muscle Cross Section features :

Back 42

- Central Nuclei

- High Cytoplasm : Nucleus Ratio