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27 Cards in this Set
- Front
- Back
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neuromuscular blocking drugs are used for
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muscle paralysis in surgery or mechanical ventilation
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name a depolarising neurmuscular blocking drug
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succinylcholine
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name 6 nondepolarizing neuromuscular blocking drugs
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tubocurarine
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*mnemonic -- the "cur" drugs are nondepolarizing neuromuscular blocking agents, name 5
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atracurium, mivacurium, pancuronium, vecuronium, rapacuronium
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is succinylcholine depolarizing or nondepolarizing?
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depolarizing
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is tubocurarine depolarizing or nondepolarizing?
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nondepolarizing
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is atracurium depolarizing or nondepolarizing?
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nondepolarizing
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is mivacurium depolarizing or nondepolarizing?
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nondepolarizing
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is pancuronium depolarizing or nondepolarizing?
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nondepolarizing
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is vacuronium depolarizing or nondepolarizing?
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nondepolarizing
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is rapacuronium depolarizing or nondepolarizing?
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nondepolarizing
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what is tubocurarine used for
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nondepolarizing neuromuscular blockade
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what agents are used to reverse neuromuscular blockade by succinylcholine?
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cholinesterase inhibitors in phase II (ex -- neostigmine)
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what phase of succinylcholine neuomuscular bloackade is reversible?
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phase II (repolarized but blocked)
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what agents are used to reverse pahse I neuromuscular blockade by succinylcholine?
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phase I Succinylcholine neuromuscular blockade cannot be reversed
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what phase of succinylcholine neuomuscular bloackade is irreversible?
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phase I Succinylcholine neuromuscular blockade cannot be reversed
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what is atracurium used for
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nondepolarizing neuromuscular blockade
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what is the effect of cholinesterase inhibitors on succinylcholine neuromuscular blockade?
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phase I: cholinesterase inhibitors potentiates the blockade phase II: cholinesterase inhibitors reverse the blockade
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what cholinesterase inhibitor is used to reverse phase II of succinylcholine neuromuscular blockade?
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neostigmine
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what is mivacurium used for
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nondepolarizing neuromuscular blockade
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what is dantrolene used for
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treat malignant hyperthermia and neuroleptic malignant syndrome
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what causes malignant hyperthermia
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use inhalation anesthetics and succinylcholine together
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what inhalation anesthetic DOES NOT cause malignanat hyperthermia?
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N2O
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what is dantrolene used for
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treat malignant hyperthermia and neuroleptic malignant syndrome
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what is neuroleptic malignant syndrome
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a toxicity of antipsychotic drugs
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what drug is used to treat malignant hyperthermia
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dantrolene
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what is the mechanism of dantrolene
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prevents release of Ca++ from saarcoplasmic reticulum of skeletal muscle
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