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10 Cards in this Set
- Front
- Back
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Name two categories of drugs used to treat MS.
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Immunomodulators and Immunosuppressants
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When should an immunosuppressant be stopped?
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If the pt. has a toxic reaction or no response to the drug.
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What is the major complication of Natalizumab?
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Fatal brain infection
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How are most immunomodulators administered?
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Self injection; you must do patient education.
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How can acute exacerbation of MS be treated?
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With corticosteroids or IV Immunoglobulin
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What are adverse effects of Interferon beta?
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Flu-like symptoms, hepatotoxicity, injection-site reactions, thyroid issues, depression/suicidal thoughts
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Why are immunomodulators preferred over immunosuppressants?
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Immunosuppressants are more toxic
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What are side effects of Mitoxantrone?
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Blue/Green tint to urine and/or sclera and/or skin, immunosuppression, heart failure, infection, liver failure
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When would the nurse hold a Mitoxantrone dose?
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If the ejection fraction of the heart is less than 50% or if other signs of CHF are present.
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What labs will be ordered before EACH DOSE of Mitoxantrone?
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CBC, Liver function tests: ALT, AST, ALP, also get the Ejection Fraction.
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