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7 Cards in this Set
- Front
- Back
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Pathology of ms |
Demyelination of focal areas |
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Features of ms |
Weakness Numbness Tinglingling Urinary urgence Blurry vision |
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Tests for ms |
Mri ( most accurate) with gadolinum to see active ms Evoked response potentials (slow,abnormal) Csf (mild pleocystosis) protein level should not exceed 100mg/dl Elevated iGg index(oligoclonal bands) |
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Tx of ms |
Disease modifying agents Interferon beta 1a Interferon beta 1b Glatiramir acetate (co polymer 1) Fingolimod Dalfampridine Decreasing acute exacerbations Interferon beta 1b Mitoxantrone(cardiotoxic) Also Methotrexate Ivig Azathioprone
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Which drugs not used in first time tx of ms |
Mitoxantrone Cyclophosphamide Natalizumab |
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Which drugs stop exacerbation of ms |
Glucocorticoids Plasma exchange |
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Which drugs are. Used to treat the complications of ms |
Spasticity beclofentizanidine,diazipam for Trigeminal neuralgia Carbamezepine ,gabapentin,pregabalin,tca antidepressants Bladder hyperactivity oxybutynin Urinary retension bethanechol Fatigue amantadine,fluoxetine. Erectile dysfunction. Sildenafil acetate |
