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80 Cards in this Set

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Choice treatment for Neisseiria Gonnorhea

High dose of Ceftriaxone

Groups at high risk for chlamydia

Twenties


Women


AA and Hispanics

How is chlammydia transferred in children?

sexual assault and verticle transmission

Complications in women with Chlammydia

Cervicitis, urethritis, proctitis, conjuntivitis, infertillity issues, upper respiratory infection in re-infection

Symptoms of Chlammydia

Clear discharge in women


Enlarged sccrotum in Men


Urethritis, proctitis, conjunctivitis, epididitis, arthritis

Diagnosis of Chlammydia

vaginal and cervical swab, mucopurrulent cervical discharge, inflamed cervix, NAAT:GCCT nucleic amplified exam

Treatment of Chlammydia

Azithromycin 1 gram/ dose



Alternative treatment of Chlammydia

Doxycycline 100mg Twice a day for 7 days

Instructions for treatment of Chlammydia

`

Abstain from sex for 7 days


treat partners within last 3 months

Treatment for Lymphogranuloma Venereum (LGV)

Doxycline 100 (PO) for 21 days


or


Erythromycin 500 g Q6H (PO)

What classifies chlammydia as complicated?

Previous STD , Diabetes, Pregnancy

Treatment of Chlammydia in pregnancy

Azithromycin


or


Amoxicillin 500 mg Q8H for 7 days

Treatment for chlammydia in children

Ethylsuccinate 50 mg/kg/day


divided Q6H for 14 days

Folllow up in chlammydia

Prevention- frequent screening


find partners past 3 months


physical exams


Retest in 3 months

chlammydia follow up in Pregnancy

Re- test in 3 weeks after therapy


and again in 3 months

Gram stain of N. Gonorrhea

Gram negative dipplococci



Risks for Gonorrhea

less than 25 y/o, risky sexual behavior, African Americans, Penial , rectal, pharyngeal, conjunctivitis

Symptoms of Gonorrhea in Males

Urethritis, epididymitis, milky discharge, dysuria

Symptoms of Gonorrhea in females

Cervicitis, Batholins Abcess Glands, Skene's ,Fitz hugh Curtis syndrome(Perihepatitis)



Gonorrhea treatment?

Ceftriaxone 250mg (Rocephin) (IM) + AZT 2g/dose 1xday

Alternate dose of Gonorrhea tretment

Rocephin (ceftriaxone) 250 mg + Doxycycline 100mg for 7 days

Treatment Of gonorrhea in the pharynx

Ceftriaxone (Rocephin) 250 mg (IM) + (AZT 1g or Doxycycline 100 mg BID X 7days

Treatment of Syphyllis

Penicillin 2.4 million units injection

Bacterial Vaginosis treatment

Metrodinazole

Anaerobes below the belt treatment

Flagyl

Anaerobes above the belt

Clindamycin


Risks for Herpes

ages 14-50


women



First Herpes infection

Primary (most severe)

Symptoms of Herpes

vessicles, Headache, fever, malaise, myalgia, (2-4 wk durations

Lifecycle of herpes outbreak

Papule-vesicle-pustule-ulcer-crust -healed

Prodromal symptoms

12-24hrs prior, localized tingling/itching (4-6 days)



Location of herpes and shedding

Vulva, penile, and perianal

When lesion are present what diseases do you test for?

Herpes and Syphillis

Treatment of Herpes (Class)

Antivirals


Acyclovir, valcyclovir, famiclovir

Acyclovir Dosage

Primary; Oral- 400mg Q8H 7-10days


Suppressive therapy: 400 mg BID


Episodal:

Valacyclovir Dosage

Primary: 1g PO BID 7 days


Suppressive : 500mg -1g QD


Episodic: 500-1g Q12-24 5 days

Famicloyvir Dosage

Primary:: 250 mg Q8H 7-10 days


Suppressive 250 mg BID


Episodic: 125-1000mg Q12-24H (divided dose) 2-4 days

Acyclovir Treatment for Herpes in AIDs

400-800 mg (PO)


Episodic : 400mg Q8H 5-10days

Famocyclovir Treatment for Herpes in AIDs

500mg (PO) Q12H


Episodic ; 500mg Q12H 5-10 days

Vacyclovir Treatment of Herpes in AIDS

500mg (PO) Q12H


Episodic 1g Q12H 5-10 days




Treatment in pregnancy

acyclovir

which drug reduces sexual transmission

Valcyclovir

What are the three types of vaginosis?

Bacterial Vaginosis (BV)


Vulvo vaginal Candidias (VVC)


Trichomonias (STD)

Normal Vaginal discharge

Clear to white


odorless


viscous


Ph 3.8-4.2

Signs and symptoms of vaginitis

discharge, itching, irritation, odor

Signs and symptoms Bacterial Vaginosis

Discharge:thin, milky, malodorous, (fishy)


pH >4.5 , possitive kOH "whiff"


high WBC



Diagnosing Vaginitis

Patient history, inspection, appearrance of d/c, collect specimenfor examination



signs and symptoms of candidias

itch, dysuria, thick (clumpy white), erythyma, inflammation, pH <4.5, negative whiff test


few to many WBC, psuedomonas hyphae

signs and symptoms of trichomatis

itchy, discharge, asymptomatic, frothy, gray/yellow d/c, malodorous, cervical petchiae, strawberry cervix, pH >4.5, positive whiff test,


Motile flagellated protozoa, many wbc

Causes of Bacterial Vaginosis

Premature Ruptured membrane, pre-mature delivery, HIV, Gonnorhea, HSV-2, post op infections, re-occurring BV.

Risks of Bacterial Vaginosis

African American, 2 or more sex partners in 6 months, douching, unprotected, decrease in lactobaccilli

Which antifungal is contraindicated in pregnancy

Fluconazole

Treatment of Bacterial Vaginosis

Metrodinazole 500 mg (PO) BID for 7 days


or gel (.75%) Q12-24H


Clindamycin cream 2% 5g @ bedtime for 7 days

TReatment of Bacterial Vaginosis in pregnancy

Clindamycin 300 mg (BID) 7 days

Organism responsible for Vulvovaginal Candidias

caused by candida Albicans

Symptoms of VVC

Vulvar pruritis, cottage cheese d/c, Satellite lesions (sometimes), dysuria, Dysparenuria,

Diagnosis of VVC

psuedohyphae, and/or budding yeasts, pH 4.0-4.5

Uncomplicated VVC

Sporadic , mild to moderate, non immunocomprimised

OTC Treatment of uncomplicated VVC

Clotrimazole 1% cream 5g intravaginally 7-14 days


or Clotrimazole 2% for 3 days

Prescrption Treatment of uncomplicated VVC

Butaconazole 2% cream 1 dose intravagin.


Nystatin 100,000 sub units vag. tablet QD 14days


Fluconazole PO 150mg 1 dose

complicated VVC

RecurrentVVC


Svere VVC, Non- albicans organism, diabetic, immunosuppressed

Treatment for reoccuring VVC

Fluconazole 100-150-200 mg PO repeated every 3 days for 7 days


or topical for 7-14 days

Treatment of severe VVC

Fluconazole 150mg Q3dys for 7-14 daysPO



Non-albicans VVC Treatment

Boric Acid 600 mg Gel Cap QD 14 days

Treatment of VVC in immunocomprimised

Topical Fluconazole 7-14 days

Risk factors fot trichomonias

Multiple sex partners, low economic,history of STD, unprotected sex

Symptoms of Trichomonias

gray/yellow/green discharge, pruritis, Cervical petachiae (strawberry cervix),can be asymptommatic. in men : gonnococcal urethritis



Diagnosis

Motile trichomonads onn wet mount

Treatment for Trichomonias

Metronidazole 2g (PO) 1 dose *pregnant


or Tinidazole 2g (PO) 1 dose

Syphillis organism

Treponema Pallidum (STI)

Syphillis transmission

Sexually transmitted and vertically transmitted (enters through skin and mucous membranes and abrasions during sex.) Most contagious in the primary stage. travels via blood stream with abillity to cross BBB. at any stage.

Primary Syphillis

Chancre stage. very contagioius. macule -papule- ulcer


heals in 3-6 weeks


lymphadenopathy


may not show positve for syphillis in testing

Secondary Syphillis

Lesions appear weeks after primary chancre.


Lasts from weeks to months


Rash Lyphadenopathy Malaise Alopecia

Latent Syphillis

Supressed, no lesions present. can happen anytime Early< 1 yr


Late >1 yr (gummatous lesions, cardiac syphillis)

Neurosyphillis

CNS invasion can happen at any stage lasting from months to years, asymptomatic

Congenital Syphillis

When T pallidum is transmitted to the baby, can cause infant death, cam be transmitted at any stage of pregnancy,


early < 2y/o late > 2y/o



Treatment of syphillis

Benzanthine Pen G 2.4 million units (IM) one dose


in PCN allergy Doxycycline 100 mg (PO) BID x 14 days

Late Latent and Tertiary Syphillis treatment

Benzanthine Penicillin G 7.2 million units(IM) divided into 3 doses once a week




PCN allergy Doxyclycline 100 mg BID PO 28days

Treatment of Neurosyphillis

Aqueous Crystalline Pen G 18-24 million units/day divided Q6H continous IV 10-14 days

Jarisch Herxeimher Reaction

fever malaise n/v chills rash, occurs 24 hrs after therapy


tx with anti pyretics