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8 Cards in this Set
- Front
- Back
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What is Waldenstrom? |
it's overproduction of IgM (Not A or G) from malignant B cells leading to hyperviscosity syndrome |
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What are symptoms of hyperviscosity? |
lethargy blurry vision and vertigo engorged blood vessels in the eye mucosal bleeding Raynaud's phenomenon |
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Do you see bony lesions with Waldenstrom? |
no, apparently it doesn't produce the OAF associated with MM
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one lab value in Waldenstrom that is helpful |
SPEP showing IgM spike |
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best initial therapy for Waldenstrom? |
plasmapharesis- similar to blast crisis, you have to draw off some of the protein |
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Long term mgmt is with... |
Rituximab |
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Or the other options are |
prednisone and cyclophosphamid |
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And then the other two drugs that can also be used in MM as well as WAldenstrom? |
bortezomib and lenalidomide |
