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12 Cards in this Set
- Front
- Back
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6 drugs commonly associated with hypersensitivity reactions |
penicillins sulfa drugs allopurinol phenytoin lamotrigine NSAIDs |
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the same drugs that cause hypersens reactions are the same ones that cause |
hemolysis (penicillins) interstitial nephritis (NSAIDs) drug-induced thrombocytopenia (penicillins) |
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the mildest reaction on the spectrum is |
morbilliform rash |
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next is |
erythema multiforme |
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treatment for morbilliform rash is |
just stop the drug
there is nothing serious and the mucous membranes are not involved |
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widespread target lesions mostly on the trunk with no mucous membrane involvement |
EM |
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2 other causes of EM |
HSV and Mycoplasma |
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treatment for EM |
can just watch it or give prednisone |
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first involvement of the mucous membranes up to 10% of bodily surface
sloughing of respiratory epithelium |
SJS |
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treatment for SJS |
IVIG is the mainstay |
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involves more than 30% of body surfaces and adds a positive Nikolsky sign with skin coming off in sheets |
TEN |
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treatment for TEN |
IVIG
steroids are NOT helpful (similar to GBS) |
