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443 Cards in this Set
- Front
- Back
upper respiratory system
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above larynx
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lower respiratory system
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below larynx
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conducting portion
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from nasal cavity to terminal bronchioles
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respiratory portion
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respiratory bronchioles and alveoli
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alveoli
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air filled pockets within lungs for gas exchange
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pulmonary ventilation
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air movement in and out of lungs
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external respiration
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gas exchange between blood and air at lungs' alveoli
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internal respiration
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gas exchange between blood and tissue cells
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respiratory epithelium
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for efficient gas exchange; very thin and high surface area
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respiratory mucosa
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epithelial layer that lines conducting portion of respiratory system
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lamina propria
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underlying layer of areolar tissue that supports the respiratory epithelium; include mucous glands and smooth muscle
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nasal hairs
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first part of filtration system found in nasal vestibule
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nasal cavity
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clean and moistened by paranasal sinuses and tears that secrete mucous; has the olfactory region in the superior portion; separated by nasal septum
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nasal septum
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separates the nasal cavity into left and right
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hard palate
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forms floor of nasal cavity, separates nasal and oral cavities
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soft palate
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extends posterior to hard palate, divides superior nasopharynx from lower pharynx
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nasal mucosa
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functions to warm and humidify air for arrival at lower respiratory organs
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pharynx
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chamber shared by digestive and respiratory systems; extends from internal nares to entrances to larynx and esophagus
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nasopharynx
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superior portion of pharynx, contains pharyngeal tonsils and openings to left and right auditory tubes
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oropharynx
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middle portion of pharynx that communicates with oral cavity
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laryngopharynx
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inferior portion of pharynx that extends from hyoid bone to entrance of larynx and esophagus
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thyroid cartilage
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Adam's apple; hyaline cartilage that forms anterior and lateral walls of larynx
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cricoid cartilage
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hyaline cartilage that forms posterior larynx
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epiglottis
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elastic cartilage that prevents entrance of bolus into respiratory tract
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vestibular ligaments
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lie within vestibular folds to protect vocal folds
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phonation
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sound production at the larynx
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articulation
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modification of sound by other structures
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trachea
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aka windpipe that extends from the cricoid cartilage into mediastinum; surrounded by cartilaginous disks
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extrapulmonary bronchi
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branches outside the lungs
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intrapulmonary bronchi
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branches within the lungs
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carina
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where the trachea bifrucates and split into primary bronchi
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primary bronchus
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one that goes into each lung branching off from trachea at the carina
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hilum
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where pulmonary nerves, blood vessels, and lymphatics enter a groove into an organ, anchored by connective tissue
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root of lung
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complex of connective tissue, nerves, and vessels in hilum
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base of lungs
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inferior portion of each lungs rest on superior of diaphragm
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secondary bronchus
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aka lobar bronchii; branch that comes off the primary bronchus
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bronchitis
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inflammation of bronchial walls causing constriction and breathing difficulty
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bronchiole
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has no cartilage and is dominated by smooth muscle
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bronchiodialation
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dilation of bronchial airways by sympathetic autonomic nervous system activation, reduces resistance
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bronchiolconstriction
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constricts bronchioles by histamine release
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asthma
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excessive stimulation and bronchioconstriction that restricts airflow
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pulmonary surfactant
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oily secretion of phospholipids and proteins that decreases alveolar surface tension allowing the lungs to expand
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respiratory distress
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difficult respiration due to alveolar collapse when pneumocytes do not produce enough surfactant
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pneumonia
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inflammation of lobules causing fluid to leak into alveoli compromising the function of the respiratory membrane
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high altitude pulmonary edema
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results from a high blood pressure in the lungs causing smooth muscle to constrict causing leakage in the lungs; tolerability and symptoms varies from person to person due to their fitness, acclimation, and genetics
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pleural fluid
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lubricates space between parietal and visceral pleura surrounding lungs
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atmospheric pressure
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weight of air that drives oxygen into lungs
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respiratory cycle
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cyclical changes in interapleural pressure operate the respiratory pump
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tidal volume
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amount of air moved in and out of lungs in a single respiratory cycle
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pnemothorax
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injury to chest wall that allows air into pleural cavity
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alelectasis
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aka collapsed lung; result of pnemothorax
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quiet breathing
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eupena, involves active inhalation and passive exhalation
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deep breathing
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use of diaphragm
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shallow breathing
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use of rib cage
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elastic rebound
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occurs when inhalation muscles relax allowing muscles and lungs to recoil returning body to original position
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hyperpnea
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aka forced breathing that involves active inhalation and exhalation; maximum levels occur in exhaustion
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respiratory minute volume
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amount of air moved per minute to measure pulmonary ventilation
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alveolar ventilation
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amount of air reaching alveoli each minute; calculated as [(tidal volume) - (anatomic dead space)] times (respiratory rate)
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anatomic dead space
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volume of air remaining in conducting passages that does not reach alveoli
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sudden infant death syndrome
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SIDS, may result from connection problems between pacemaker complex and respiratory center
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cranial nerve IX
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glossopharyngeal nerve that is stimulated by changes in blood pH or the pressure of oxygen
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cranial nerve X
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vagus nerve from aortic bodies stimulated by blood pH or pressure of oxygen
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hypercapnia
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increase in arterial carbon dioxide pressure that stimulates breathing
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hypoventilation
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abnormally low respiration rate
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hyperventilation
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excessive breathing that causes low pressures of carbon dioxide which stimulates chemoreceptors to decrease respiratory rate
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barocepter reflexes
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affected by blood pressure; when it falls, respiration increases
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Herring-Breor reflexes
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involved in forced breathing to prevent over-expansion of lungs
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protective reflexes
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triggered by receptors in respiratory tract to cough, sneeze and laryngeal spasm when exposed to chemical irritants and mechanical stimuli
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apnea
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suspended respiration followed by explosive exhalation to clear airways by sneezing or coughing
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laryngeal spasm
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temporary closure of airways to prevent foreign particles and substances from entering
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emphysema
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breakdown of alveolar walls, affects individuals over age 50, dependent on exposure to respiratory irritants such as cigarette smoke
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nervous system
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includes all neural tissues in the body, including brain, spinal cord
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neurons
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cells that send and receive signals as the functional unit; perform all communication, information processing and control functions of the nervous system
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neuroglia
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aka glial cells; cells that support and protect neurons
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central nervous system
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brain and spinal cord enclosed in bony coverings
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peripheral nervous system
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includes nerves and ganglia
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nerve
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bundle of axons in connective tissue for the PNS; examples include spinal and cranial nerves
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ganglion
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swelling masses of cell bodies in a nerve surrounded by neuroglia; for the PNS
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cranial nerves
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connect to brain
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spinal nerves
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exiting spinal cord
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afferent division
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sensory; carries sensory information from PNS sensory to CNS
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visceral motor division
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has effectors of cardiac, smooth muscle and glands
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receptors
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detect changes or responds to stimuli
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effector
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responds to efferent signals, organs that carry out responses
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somatic nervous system
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controls skeletal muscle contractions
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autonomic nervous system
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controls subconscious actions of smooth and cardiac muscles and gradular secretions
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sympathetic division
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has a stimulating effect
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parasympathetic division
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has a relaxing effect
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sensory neuron
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afferent neuron; detects changes in body and external environment; information transmitted into brain or spinal cord
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interneuron
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association neurons that integrate information in-between sensory and motor pathways; found in brain, spinal cord, and autonomic ganglia; involved in higher function of memory, planning, and learning
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motor neuron
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efferent neuron; sends signals out to muscles and gland cells
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excitability
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aka irritability; ability to change and respond to changes in body and stimuli
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conductivity
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produce travelling electrical signals
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secretition
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release of chemical neurotransmitters when stimulated by an electrical signal
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soma
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cell body of neuron that has a single central nucleus with large nucleolus
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dendrite
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receive signals and branch off the cell body
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neurofilaments
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act as microfilaments
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neurotubules
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replacement of microtubules
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neurofibrils
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bundles of neurofilmanets that provide support for dendrites and axon
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Nissel bodies
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dense areas of RER and ribosomes that make neural tissue appear gray
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dendrititic spine
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fine processes on a dendrite that receive information from other neurons; 80-90% of neuron surface area
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nerve fiber
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propagates signal to target cell
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axon hillock
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where the cell body meets the axon and attaches to initial segment
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axoplasm
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cytoplasm of axon that contains neurotubules, neurofibrils, enzymes, and organelles
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axolemma
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specialized cell membrane that covers axoplasm
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multipolar neuron
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most common in CNS, includes all skeletal muscle motor neurons; many dendrites to one axon
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bipolar neuron
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one way directional flow that has one dendrite to one axon; found in olfactory, retina, ear and other special sensory organs
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unipolar neuron
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found in sensory neuron of PNS; sensory from skin and organs to spinal cord
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anaxonic neuron
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more rare; many dendrites to no axons; help in visual processes and found in brain and senses organs
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fast anterograde axonal transport
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moves in either direction up to 400 mm/day for organelles, enzymes, vesicles, and small molecules
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fast retrograde
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moves recycled materials and pathogens
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slow axonal transport
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aka plasmic flow; moves cytoskeletal and new axoplasmic materials at 10 mm/day during repair and regeneration in damaged axons
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neuroglia
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half the volume of the nervous system that preserves physical and biochemical structure of neural tissue and are essential to survival and function of neurons
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ependymal cells
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cells with highly branched processes; contact neuroglia directly; form epithelium called ependyma; line central canal and ventricles of the brain to secrete CSF, circulate and monitor CSF, and contains some stem cells for repair
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cerebral spinal fluid
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provides nutrients to brain, provides cushion
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astrocytes
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large cell bodies with many processes that maintain conditions of central nervous system with cerebral spinal fluid, conversion of glucose to lactate, development of new nerves, and brain blood barrier
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oligodendrocytes
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smaller cell bodies that wrap around axons to form myelin sheaths
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microglia
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smallest neuroglia that come from monocytes and are found in areas of infection, trauma, or stroke
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Schwann cells
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myelinate fibers of PNS
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satellite cells
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cells found in neuroglia, but function is unknown
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myelin
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insulating layer around a nerve fiber; composed of 20% protein and 80% lipids; white matter
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nodes of ranvier
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gaps between myelin segments
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initial segment
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area between first Schwann cell
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trigger zone
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area between initial segment and axon hillock where signal begins
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slow signals
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provide information to stomached and dilate pupil
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fast signals
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supply skeletal muscles and transport sensory signals for vision and balance
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presynaptic neuron
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first neuron that releases neurotransmitters to stimulate the second neuron
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postsynaptic neuron
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second neuron that receives neurotransmitters to start action potential and responds
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synaptic cleft
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gap between presynaptic membrane and post synaptic membrane
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synaptic knob
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expanded area of axon of presynaptic neuron that releases neurotransmitters
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synaptic vesicles
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storage area in neurons for neurotransmitters
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neurotransmitters
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chemical messengers that are released at the presynaptic membrane to affect receptors at the post synaptic membrane; broken down by enzymes and reassembled at synaptic knob
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electrical synapse
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direct physical contact between cells locked by gap junctions; allow ions to pass between cells and are found in brain, eye, and ciliary ganglia
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chemical synapse
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signal transmitted across a gap by chemical neurotransmitters; found in most synapses between neurons; cells are not in direct contract
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neuromuscular junction
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synapse between neuron and muscle
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neuroglandular junction
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synapse between neuron and gland
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connexons
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gap junctions that interlock electrical synapses
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excitatory neurotransmitter
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causes depolarization of post synaptic membranes and promotes action potentials
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inhibitory neurotransmitter
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cause hyperpolarization of post synaptic membranes; suppresses action potentials
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cholinergic synapse
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any synapse that releases acetylcholine
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acetylcholine
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a neurotransmitter that usually promotes action potentials; inhib8its at neuromuscular junctions
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axodendritic synapse
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axon connects to dendrite
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axosomatic synapse
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axon connects directly to soma
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axoaxonic synapse
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axon connects to another axon
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neuromodulator
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other chemicals released by synaptic knob that are long term, have multiple steps, may act with or without a neurotransmitter
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norepinephrine
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released by adrenergic synapses as a an excitatory and depolarizing effect; widely distributed in brain and portions of autonomic nerve system
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dopamine
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CNS neurotransmitter that may be excitatory or inhibitory; involved in Parkinson's disease or cocaine use
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serotonin
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CNS neurotransmitter that affects attention and emotional states
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Gama aminobutyric acid
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inhibitory effect, function is not well known
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monoamines
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synthesized by replacing amino acids with another functional group, includes catecholamine and indolamines
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catecholamines
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epi, NE, and dopamine
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indolamines
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serotonin and histamine
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neuropeptides
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chains of 2-40 amino acids that are stored in secretory granules called dense core vesicles; act at lower concentrations and have longer lasting effects; some released from non-neural tissue and may function as hormones
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neural pool
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interneurons that share specific body function
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discharge zone
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single cell can produce firing
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facilitated zone
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single cell can only make it easier for a post synaptic cell to fire
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diverging circuit
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one input, lots of outputs; found in stretch reflex
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converging circuit
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input from many fibers to one neuron
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reverberating circuits
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neurons stimulate each other in linear sequence but one cell restimulates the first cell to start the process over
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parallel after discharge circuit
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higher order pathway that has input neurons that undergo several pathways and continues stimulation after initial input firing has ceased
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engram
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aka memory trace; physical basis of memory as a synaptic pathway
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immediate memory
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ability to hold something in thoughts for a few seconds; used in reading, sense of present; uses reverberating circuits
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short term memory
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lasts from a few seconds to a few hours; uses reverberating circuits; facilitation makes memory retention easier
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tetanic stimulation
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rapid repetitive signals that cause calcium to build up increasing likelihood of firing neuron; used as part of facilitation
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post-tetanic potentiation
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jogging memory; calcium levels in synaptic knob remain elevated; little stimulation required for memory recovery
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declarative long term memory
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retention of facts as text
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procedural long term memory
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retention of motor skills
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long term memory
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physical remodeling of synapses with new branches of axons or dendrites; molecular changes for the long term such as more neurotransmitter receptors, more proteins, nitric oxide, and more neurotransmitters
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Alzheimer's disease
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memory loss for recent events, moody and combative, loss of ability to walk, talk, or eat; diagnosis confirmed at autopsy by atrophy of gyri in cerebral cortex, presence of neurofibrillary tangles and senile plaques; also degeneration of cholinergic neurons, deficiency of ACh and nerve growth factor
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Parkinson's disease
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chronic and progressive degenerative disease of brain that impairs motor control, speech, and other functions; degeneration of dopamine releasing neurons; involuntary muscle contractions like pill rolling motion, facial rigidity, slurred speech, illegible handwriting, and slow gait; treated by dopamine precursors, MAO inhibitor to slow neural degeneration, or surgical techniques, usually drugs and physical therapy
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rabies
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retrograde flow from the bite of an animal that moves into peripheral tissues; from there, virus enters synaptic knobs and peripheral axons, then moves to CNS and is then fatal
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primary tumor
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75% of tumors; originate in CNS; in adults results from division of abnormal neuroglia; children receive tumors from division of stem cells until age 4
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secondary tumor
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tumor that originates from metastasis of cancer cells that originate elsewhere
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tumor
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abnormal growth of tissue with various symptoms depending on location; treated with radiation, surgery, or a combination of the two
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medullary cone
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aka conus medullaris; tapered end tip of spinal cord
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cauda equina
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from L2 to S5 nerve; roots resemble horse's tail
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enlargement
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amounts of gray matter in segments involved with sensory and motor nerves of limbs
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cervical enlargement
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nerves of shoulder and upper limbs
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lumbar enlargement
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nerves of pelvis and lower limbs
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denticulate ligaments
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stabilize spinal cord from side to side; extend from pia mater to dura mater
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ventral root
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contains axons of motor neurons
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dorsal root
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contains axons of sensory neurons
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dorsal root ganglia
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contains cell bodies of sensory neurons
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spinal nerves
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where dorsal and ventral roots join
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mixed nerve
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a nerve that carries both afferent and efferent fibers
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spinal meninges
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specialized protective membranes that isolate spinal cord from surroundings
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meningitis
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viral or bacterial infections of meninges causing inflammation; creates symptoms of neck problems, fatigue, and high fever
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dura mater
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tough collagenous membrane surround by epidural space, filled with fat and blood vessels
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arachnoid mater
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layer of simple squamous epithelium lining dura mater and loose mesh of fibers filled with cerebral spinal fluid
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pia mater
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delicate membrane adherent to spinal cord; filium terminale and denticulate ligaments anchor the spinal cord
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spina bifida
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failure of vertebral arch to close covering spinal cord; folic acid consumption for mother decreases risk; congenital defect in 1 baby out of 1000
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gray matter
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neuron cell bodies with little myelin; area of integration and command initiation; organized into nuclei
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white matter
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myelinated axons that carry information from place to place; organized into columns
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white columns
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aka funiculi; bundles of myelinated axons that carry signals up and down to and from brainstem
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tracts
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aka fasciculi; fibers with similar origin, destination, and function; found in the CNS; bundles of axons
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nuclei
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functional groups of gray matter as a collection of cell bodies in the CNS, specifically deep in the brain
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poliomyelitis
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caused by polio virus spread by fecally contaminated water; weakness progresses to paralysis and respiratory arrest; destruction of motor neurons and skeletal muscle atrophy
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amylotrophic lateral sclerosis
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aka Lou Gehrig's disease; sclerosis of spinal cord due to astrocyte failure to reabsorb glutamate neurotransmitters; leads to paralysis and muscle atrophy; not infectious
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epineurium
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outer layer that covers nerves; dense network of collagen fibers
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perineurium
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middle layer that surrounds fascicle; divides nerves into fascicles; blood vessels penetrate only to perineurium
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endoneurium
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inner layer that separates individual nerve fibers surrounds individual axons
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dorsal ramus
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contains somatic and visceral motor fibers, innervates the back
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ventral ramus
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larger branch, innervates ventrolateral structures and limbs
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interoceptors
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sense internal environment
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exteroceptors
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sense external environment
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proprioreceptors
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senses body position in space, found in joints, used to detect movement
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dermatome
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bilateral region of skin monitored by specific pair of spinal nerves
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peripheral neuropathy
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regional loss of sensory or motor function causing pain and numbness in hands and feet; caused by trauma, compression, infections, metabolic problems, and exposure to toxins; treated with medication and symptoms improves over time
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shingles
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skin eruptions along path of nerve caused by varicella-zoster virus that remains for life in dorsal root ganglia; occurs after age 50 if immune system is compromised; no special treatment
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nerves plexus
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complex interwoven network of nerve fibers formed from blended fibers of ventral rami of adjacent spinal nerves; controls skeletal muscles of neck and limbs
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cervical plexus
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includes ventral rami of spinal nerves C1-C5; innervates neck, thoracic cavity, and diaphragmatic muscles
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brachial plexus
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includes ventral rami of spinal nerves C5-T1; innervates pectoral girdles and upper limbs
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lumbar plexus
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includes ventral rami of spinal nerves T12-L4
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sacral plexus
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includes ventral rami of spinal nerves L4-S5
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sciatica
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disturbance of sciatic nerve causing shooting pains down leg
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innate reflexes
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basic neural reflexes, formed before birth
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acquired reflexes
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rapid automatic reflexes, learned motor patterns
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somatic reflexes
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involuntary control of nervous system such as superficial reflexes of skin, mucous membranes, and stretch or deep tendon reflexes
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visceral reflexes
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autonomic reflexes that control systems other than muscular system
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monosynaptic reflex
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sensory neuron synapses directly onto motor neuron
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polysynaptic reflex
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at least interneuron between sensory and motor neuron
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spinal reflex
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reflex occurs in spinal cord
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cranial reflex
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reflex occurs in brain
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muscle spindles
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bundles of small specialized interfusal muscle fibers innervated by sensory and motor neurons surrounded by extrafusal muscle fibers that maintain tone and contract muscles
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postural reflexes
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stretch reflex that maintains normal upright posture where a stretched muscle responds by contracting automatically maintaining balance
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tendon reflex
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prevents skeletal muscles from developing too much tension and breaking tendons
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withdrawal reflex
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move body part away from pain or pressure stimulus; strength and extent of response dependent on intensity and location of stimulus
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flexor reflex
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polysynaptic reflex arc; neural circuitry in spinal cord controls sequence and duration of muscle contractions
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ipsilateral reflex arc
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stretch, tendon, and withdrawal reflex occurs on the same side of body as stimulus
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contralateral reflex arc
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reflex arc where response occurs on the opposite side of the stimulus
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Babinski reflex
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stroking the soles of the foot; normal for infants, may indicate CNS damage in adults
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spinal cord trauma
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occurs in traffic accidents, leads to paralysis, poses risk of respiratory failure, spinal shock, post-traumatic infarction
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neurological assessment
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evaluates mental status, cranial nerve function, sensory function, reflex function, autonomic status, and cerebral vasculature by looking at special senses, general senses, motor function, deep tendon reflexes, and level of consciousness
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cerebellum
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muscle coordination; coordinates somatic motor process; contains 50% of the neurons; connected to brainstem by peduncles; work at evaluating sensory input, timekeeping, pitch and planning tasks
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cerebrum
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conscious thought processes; intellectual functions; memory storage and processing; 83% of brain volume; composed of four lobes
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diencephalon
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composed of the thalamus and hypothalamus
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thalamus
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relay and process centers for sensory information from cerebellum to motor cortex; emotion and memory function
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hypothalamus
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centers controlling emotions, autonomic functions and hormone production, such as autonomic NS, thermoregulation, food and water intake, sleep and circadian rhythms, and memory
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mesencephalon
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processing of visual and auditory data, generate somatic motor reflexes, maintains consciousness
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pons
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relays sensory information to cerebellum and thalamus, subconscious motor centers like posture, sleeping, hearing, balance, taste, ye movements, facial expression, facial sensation, respiration, swallowing, and bladder control; bulge in brainstem
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medulla oblongata
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relays sensory information to thalamus and brain stem, autonomic centers for visceral functions such as cardiac centers, vasomotor centers, respiratory centers, and reflex centers
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rostral
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towards the forehead
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caudal
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towards the spinal cord
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gyri
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folds and protrusions of the brain
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sulci
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grooves of the brain
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cortex
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surface layer of gray matter of the brain
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epidural hemorrhage
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blood forced between dura mater and cranium
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subdural hemorrhage
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more common to occur; blood forced between dura and arachnoid mater; gradual, variable, hard to diagnose
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choroid plexus
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produces cerebral spinal fluid
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blood brain barrier
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isolates CNS from general circulation by using tight junctions; prevents diffusion of materials between endothelial cells; allows only small lipid soluble materials like oxygen, carbon dioxide, nicotine and anesthetics through
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blood-CSF barrier
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prevents free access of substances to CNS; found at the choroid plexus using tight junctions
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superior peduncle
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output to midbrain, thalamus, and cortex
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middle peduncle
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input from cerebral cortex and inner ear
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inferior peduncle
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spinocerebellar tracts for proprioception
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tegmentum
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connects to cerebellum and helps control fine movements through red nucleus
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substantia nigra
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sends inhibitory signals to basal ganglia and thalamus
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central gray matter
|
responsible for pain awareness
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superior colliculus
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tracks moving objects, blinking, pupillary and head turning reflexes
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inferior colliculus
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reflex of turning head to sounds
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reticular formation
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clusters of gray matter scattered throughout pons, midbrain, and medulla; regulate balance and posture, as well as cardiac and vasomotor centers; regulate sleep and conscious attention
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frontal lobe
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responsible for voluntary motor functions, planning, mood, smell, and social judgment
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parietal lobe
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receives and integrates sensory information, such as touch, pressure, and pain
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occipital lobe
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visual center of brain
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temporal lobe
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areas for hearing, smelling, learning, memory, and emotional behavior
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projection tract
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from brain to spinal cord, forms internal capsule
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commissural tract
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cross to opposite hemisphere e.g. corpus callosum and anterior and posterior commisures
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association tracts
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connects lobes and gyri within a hemisphere
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stellate cells
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cells with dendrites that project in all directions
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pyramidal cells
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axons pass out of these areas
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basal nuclei
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masses of gray matter deep to cortex; includes caudate nucleus, putamen, and globus pallidus
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limbic system
|
includes amygdala, hippocampus, and cingualte gyrus
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electroencephalogram
|
records voltage changes from postsynaptic potentials in cerebral cortex
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alpha wave
|
occurs when awake or resting with eyes closed
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beta wave
|
eyes open, performing mental tasks, intense concentration
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theta wave
|
sleep or emotional stress; found in children and frustrated adults
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delta wave
|
deep sleep wave
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sleep paralysis
|
inhibition of muscular activity
|
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REM sleep
|
rapid eye movement under eyelids; vital signs increase; EEG resembles awake person; dreams and penile erection occur
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|
agnosia
|
results from lesion to temporal lobe; causes inability to recognize objects
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prosopagnosia
|
inability to recognize faces
|
|
anterograde amnesia
|
no new memories form, usually an issue with the hippocampus
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retrograde amnesia
|
can't remember old memories
|
|
hippocampus
|
organizes sensory and cognitive information into a new memory
|
|
amygdala
|
emotional memory
|
|
prefrontal cortex
|
controls expression of emotion
|
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homunculus
|
map of the brain that shows receptors dedicated to specific parts of the body
|
|
Wernicke area
|
permits recognition of spoken and written language, creates plans of speech
|
|
Broca area
|
generates motor signals for larynx, tongue, cheeks, and lips; transmits to primary motor cortex for action
|
|
cerebral lateralization
|
separation of hemispheres to favor particular skills
|
|
aphasia
|
language deficit from lesions in same hemisphere as Wernike or Brocca area
|
|
nonfluent aphasia
|
lesion to Brocca area resulting in slow speech, difficulty in choosing words
|
|
fluent aphasia
|
lesion to Wernike area resulting in normal and excessive speech, but it makes little sense
|
|
anomic aphasis
|
speech and understanding are normal, but text and pictures make no sense
|
|
left hemisphere
|
categorical hemisphere that is specialized for language, sequential and analytical reasoning
|
|
right hemisphere
|
representational hemisphere for perceiving information more hollistically, perception of spatial relationship, patterns, comparison of special sense, imagination, and insight, music and artistic skills
|
|
olfactory nerve
|
1 responsible for sense of smell
|
|
optic nerve
|
2 provides vision and damage causes blindness in visual field
|
|
oculomotor nerve
|
3 responsible for eye movement, opening of eyelid, constriction of pupil and focusing; damage causes drooping eyelid, dilated pupils, double vision, difficulty in focusing, and inability to move eyes in certain directions
|
|
trochlear nerve
|
4 eye movement of the superior oblique muscle; damage causes double vision and inability to rotate eye inferiorly
|
|
trigeminal nerve
|
5 sensory to face, such as touch, pain, and temperature, and muscles of mastication; damage produces loss of sensation and impaired chewing
|
|
abducens nerve
|
6 produces eye movement via lateral rectus muscle; damage results in inability to rotate eye laterally
|
|
facial nerve
|
7 motor - facial expressions, salivary glands, tears, nasal and palatine glands; sensory - taste on anterior 2/3 of tongue; damage produces sagging facial muscles and disturbed sense of taste (no sweet and salty)
|
|
vestibulocochlear nerve
|
8 provides hearing and sense of balance; damage produces deafness, dizziness, nausea, and loss of balance
|
|
glossopharyneal nerve
|
9 responsible for swallowing, salivation, gagging, control of blood pressure, and respiration; also sense 1/3 of tongue; damage results in loss of bitter and sour taste and impaired swallowing
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|
vagus nerve
|
10 travels from cranium to many viscera such as lungs, heart, liver, stomach, spleen, kidney, and intestines; responsible for swallowing, speech, and regulation of viscera; damage causes hoarseness or loss of voice, impaired swallowing and can be fatal if both nerves are cut
|
|
accessory nerve
|
11 swallowing, head, neck, and shoulder movement; damage causes impaired head, neck, shoulder movement; head turns toward injured side
|
|
hypoglossal nerve
|
12 tongue movements for speech, food manipulation and swallowing; if both are damaged - can't protrude tongue
|
|
trigeminal neuraglia
|
aka tic doulereux; recurring episodes of intense stabbing pain in trigeminal area such as the mouth or nose; pain triggered by touch, drinking, or washing face; treatment may require cutting nerve
|
|
bell's palsy
|
disorder of facial nerve causes paralysis of facial muscles on one side; may appear abruptly with full recovery within 3-5 weeks
|
|
preganglionic fibers
|
in brain and spinal cord, axons of preganglionic neurons, leave CNS and synapse on ganglionic neurons of the ANS visceral motor neurons
|
|
autonomic ganglia
|
ganglionic neurons innervate visceral effectors such as smooth muscle, cardiac muscle, glands, and adipose tissue
|
|
post ganglionic fibers
|
axons of ganglionic neurons in the ANS's visceral motor system, leave collateral ganglia, extend through abdominopelvic cavity
|
|
enteric nervous system
|
third division of ANS, extensive network in digestive tract walls, complex visceral reflexes
|
|
collateral ganglia
|
anterior to vertebral bodies, contain ganglionic neurons that innervate tissues in abdominopelvic cavity
|
|
splanchnic nerve
|
formed by preganglioninc fibers that innervate collateral ganglia in the dorsal wall of abdominal cavity, originate as paired ganglia
|
|
celiac ganglion
|
pair of interconnected masses of gray matter that may form single mass or many interwoven masses that innervate stomach, liver, gallbladder, pancreas, and spleen
|
|
suprarenal medullae
|
very short axons that release neurotransmitters into bloodstream, function as hormones to affect target cells throughout body
|
|
ganglionic neurons
|
release neurotransmitters at specific target organs
|
|
telodendria
|
sympathetic varicosities that resemble strings of pearl that have neurotransmitter vesicles for the sympathetic system
|
|
alpha 1
|
alpha receptor that releases intracellular calcium ions from reserves in endoplasmic reticulum, has an excitatory effect on target cell
|
|
alpha 2
|
lowers cAMP levels in cytoplasm, inhibitory effect on cell, helps coordinate sympathetic and parasympathetic activities
|
|
beta receptors
|
affect membranes in many organs, triggers metabolic changes in target cell, stimulation increase intracellular cAMP levels
|
|
beta 1
|
increases metabolic activity
|
|
beta 2
|
triggers relaxation of smooth muscles along respiratory tract
|
|
beta 3
|
leads to lipolysis
|
|
lipolysis
|
break down triglycerides in adipocytes
|
|
cholinergic sympathetic terminals
|
innervate sweat glands of skin and blood vessels of skeletal muscles and brain; stimulate sweat gland secretion and dilate blood vessels
|
|
nitroxidergic synapses
|
release nitric oxide as neurotransmitter; neurons innervate smooth muscle in walls of blood vessels in skeletal muscle and the brain; produce vasodilatation and increased blood flow
|
|
autonomic nuclei
|
contained in mesencephalon, pons, and medulla oblongata
|
|
terminal ganglion
|
of the parasympathetic system; near target organ, usually paired
|
|
intramural ganglion
|
of the parasympathetic system; embedded in tissues of target organs as clusters of ganglion cells
|
|
anabolic system
|
stimulation increases nutrient content of food and allows cells to absorb more nutrients
|
|
muscarinic receptors
|
at cholinergic neuromuscular or neuroglandular junctions for the parasympathetic and a few cholinergic junctions of the sympathetic system, contain G proteins, have a longer lasting effect than nicotine receptors, can be excitable or inhibited
|
|
nicotinic receptors
|
on surfaces of ganglion cell and exposure to Ach causes excitation of ganglionic nerve or muscle fiber
|
|
nicotine
|
binds to nicotinic receptors and target autonomic ganglia and skeletal neuromuscular junctions; can cause vomiting, diarrhea, high blood pressure, rapid heart rate, sweating, profuse salivation, convulsions, and may result in coma or death
|
|
muscarine
|
binds to muscarinc receptors; targets parasympathetic neuromuscular or neuroglandular junctions; can cause salivation, nausea, vomiting, diarrhea, constriction of respiratory passages, low blood pressure, and slow heart rate
|
|
dual innervation
|
when the parasympathetic and sympathetic systems compete for control over a common visceral organ
|
|
autonomic plexus
|
nerve networks in the thoracic and abdominopelvic cavities that are formed by sympathetic postganglionic fibers and parasympathetic preganglionic fibers
|
|
cardiac and pulmonary plexuses
|
autonomic fibers entering thoracic cavity intersect for control of heart and lungs
|
|
esophageal plexus
|
descending branch of vagus nerve meet the splanchnic nerves
|
|
celiac plexus
|
innervates viscera within abdominal cavity
|
|
hypogastric plexus
|
innervates digestive, urinary, and reproductive organs of pelvic cavity
|
|
autonomic tone
|
background level of activity that can be affected by dual innervation
|
|
long reflexes
|
autonomic equivalents of polysynaptic reflexes; visceral sensory neurons deliver information to CNS along dorsal root of spinal nerves and ANS carries motor commands to visceral effectors; found in the majority of organs
|
|
short reflexes
|
bypass CNS by using sensory neurons and interneurons located within autonomic ganglia; controls simple motor response with localized effects; found in the digestive system
|
|
sympathomimetrics
|
enhance activity of sympathetic system, stimulates receptors or increase NE release
|
|
sympatholytics
|
suppress sympathetic activity by blocking receptors or inhibit NE release
|
|
parasympathomimetrics
|
enhance parasympathetic activity
|
|
parsympatholytics
|
suppress parasympathetic activity
|
|
Prozac
|
blocks reuptake of serotonin to prolong its mood elevating effect
|
|
MAO inhibitors
|
interferes with breakdown of monoamine neurotransmitters
|
|
caffeine
|
competitively competes with adenosine at the receptor site to prevent sleepiness
|
|
sensory transduction
|
convert stimulus energy into nerve energy
|
|
receptor potential
|
local electrical change in receptor cell
|
|
adaptation
|
conscious sensation declines with continued stimulation
|
|
intensity
|
frequency, based on the number of fibers and which fibers
|
|
duration
|
change in firing frequency over time
|
|
phasic receptor
|
burst of activity and quickly adapt, such as the smell and hair receptors
|
|
tonic receptor
|
adapt slowly, generate impulses continually, such as proprioceptors
|
|
general senses
|
widely distributed throughout the body
|
|
special senses
|
senses limited to the head
|
|
unencapsulated nerve endings
|
dendrites are not wrapped in connective tissue
|
|
hair receptors
|
monitor movements of hair
|
|
encapsulated nerve endings
|
dendrites wrapped by glial cells or connective tissue
|
|
tactile corpuscles
|
phasic receptors for light touch and texture
|
|
krause end bulb
|
phasic receptor for touch in mucous membranes
|
|
lamellated corpuscles
|
phasic receptors that respond to deep pressure, stretch, tickle, and vibrations
|
|
ruffini corpuscles
|
tonic receptors that respond to heavy touch, pressure, joint movements, and skin stretching
|
|
1st order neuron
|
afferent neuron that detects touch, pressure, and proprioception on large, flat, myelinated axon and heat and cold on small unmyelinated slow fibers
|
|
2nd order neuron
|
decussation to opposite side in spinal cord or medulla/pons end in thalamus, except for proprioception (cerebellum)
|
|
3rd order neuron
|
thalamus to primary somesthetic cortex of cerebrum
|
|
nocioreceptors
|
allow awareness of tissue injuries, found in all tissues except the brain
|
|
somatic pain
|
comes from skin, muscles, and joints
|
|
visceral pain
|
pain that comes from stretch, chemical irritants, or ischemia of viscera
|
|
spinoreticular tract
|
pain signals reach reticular formation, hypothalamus, and limbic system triggering visceral, emotional, and behavioral reactions
|
|
referred pain
|
misinterpreted pain that is assume from the brain, usually a slow and deep pressure
|
|
endogenous opiods
|
include painkillers, analgesics, enkephalins, endorphins, and dynorphins produced by CNS under stress to act as neuromodulators to block transmission of pain
|
|
spinal gating
|
stopping pain signals from the dorsal horn
|
|
gustation
|
sensation of taste resulting from action of chemicals on taste buds
|
|
filiform
|
type of lingual papillae that senses texture
|
|
fungiform
|
papillae found at the tips and sides of tongue
|
|
foliate
|
papillae without any taste sensation
|
|
vallate
|
aka circumvallate; conbtains 1/2 of taste buds, found at rear of tongue
|
|
umami
|
taste of amino acids (MSG)
|
|
mouth feel
|
detected by lingual nerves in papilla that senses for texture, aroma, temperature, and appearance
|
|
sound
|
audible vibrations of molecules
|
|
pinna
|
fleshy auricle directs air vibration down external auditory meatus
|
|
cerumen
|
earwax formed from glandular secretitions and dead cells
|
|
auditory tube
|
aka eustachian tube connects to nasopharynx and helps with equalizing air pressure on tympanic membrane
|
|
bony labyrinth
|
passageways in temporal bone that make up the inner ear
|
|
inner hair cell
|
stereocilia in the organ corti that assist in hearing
|
|
outer hair cell
|
adjust cochlear responses to different frequencies and increases auditory precision
|
|
tympanic membrane
|
has 18x the area of the oval window; used to transfer sound to the ossicles to the endolymph
|
|
tensor tympani
|
muscle that tenses tympanic membrane to prevent hearing loss during loud sounds
|
|
stapedius muscle
|
reduces mobility of stapes in response to slowly building sounds
|
|
equilibrium
|
control of coordination and balance
|
|
static equilibrium
|
perceived by macula in response to head orientation
|
|
dynamic equilibrium
|
perception of motion or acceleration using macula or cristae
|
|
macula
|
hair cells with stereocilia and kinocilium buried in otolith membrane
|
|
otoliths
|
add to the density and inertia to enhance the sense of gravity and motion
|
|
cristae ampullaris
|
hair cells buried In a mound of gelatinous membrane; orientation causes ducts to be stimulated by rotation in different planes
|
|
vestibular cortex
|
awareness of spatial orientation and movement
|
|
vision
|
perception of light emitted or reflected from objects in the environment
|
|
eyebrows
|
provide facial expression
|
|
eyelids
|
aka palpebra, block foreign objects, help with sleep, moisten eyes; consist of orbicularis oculi muscle and tarsal plate
|
|
tarsal glands
|
secrete oil to prevent tear evaporation
|
|
eyelashes
|
keep debris from eye
|
|
conjunctiva
|
transparent mucous membrane that lines eyelids and covers anterior surface of eyeball except cornea; richly innervated and vascular so heals quickly
|
|
lacrimal apparatus
|
provides tears to wash away foreign particles, help with diffusion of gas and contains antibacterial enzyme
|
|
fibrous layer
|
outer tunic layer that contains sclera and cornea
|
|
vascular layer
|
middle tunic that contains choroid, ciliary body, and iris
|
|
internal layer
|
layer that contains retina and optic nerve
|
|
cornea
|
transparent cover on anterior surface of eyeball
|
|
aqueous humor
|
serous fluid posterior to cornea, anterior to lens; produced by ciliar body and flows to posterior chamber through pupil to anterior chamber and is reabsorbed by the canal of Schelmm
|
|
lens
|
changes shape to help focus light
|
|
vitrous humor
|
jelly filled space between lens and retina
|
|
cataracts
|
clouding of the lens caused by aging, diabetes, smoking, and UV light
|
|
glaucoma
|
death of retinal cells due to elevated pressure within the eye, leads to obstruction of scleral venous sinuses, colored halos, and dimness of vision
|
|
retina
|
forms as an outgrowth of the diencephalon, attached at optic disc, pressed against rear of eyeball by vitreous
|
|
detached retina
|
caused by a blow to the head or lack of vitreous humor, results in blurry areas in the field of vision, disrupts blood supply and can lead to blindness
|
|
macula lutea
|
cells on visual axis of eye that are visual under an opthalmoscopic exam
|
|
fovea centralis
|
center of macula; finely detailed images due to packed receptor cells
|
|
optic disc
|
blind spot formed where the optic nerve exits the posterior surface of the eyeball leading to no receptor cells
|
|
pupillary constrictor
|
smooth muscle encircles the pupil caused by parasympathetic stimulation
|
|
pupillary dilator
|
spoke like myoepithelial cells dilate pupil during sympathetic stimulation
|
|
photopupillary reflex
|
both pupils constrict if one eye is illuminated as a type of consensual reflex
|
|
principle of refraction
|
light striking the cornea is bent unless it enters at a 90 degree angle
|
|
near response
|
allows eyes to focus on nearby objects due to convergence of eyes and constriction of pupil
|
|
emmetropia
|
2 planes looking at distant objects
|
|
hyperopia
|
focal point forms past the fovea, farsighted, eyeball is too short; corrected with convex lenses
|
|
myopia
|
focal point forms too soon, nearsighted, eyeball is too long; corrected with concave lenses
|
|
rod cells
|
used during night vision, photoreceptor that has an outer segment with a stack of coin-like membranous discs studded with rhodopsin pigment molecules
|
|
cone cells
|
used for color vision, has an outer segment tapered to a point
|
|
rhodopsin
|
pigment in rods that have absorption peak at 500 nm, has the opsin and retinal portion; converts from cis to trans
|
|
photopsin
|
pigment in cones that have different amino acids that determine wavelength of light absorbed
|
|
duplicity theory
|
states that a single type of receptor is incapable of providing high sensitivity and high resolution
|
|
scotopic system
|
used for night vision, involves neuronal convergence for motion detection
|
|
photoptic system
|
used in day vision, no neuronal convergence
|
|
blue cones
|
have peak sensitivity at 420 nm
|
|
green cones
|
have peak sensitivity at 531 nm
|
|
red cones
|
have peak in the orange yellow range at 558 nm
|
|
color blindness
|
lack of a photopsin, sex linked recessive disease that causes one to be unable to distinguish red-green
|
|
depth perception
|
ability to judge distance to objects by using two images
|