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443 Cards in this Set

  • Front
  • Back
upper respiratory system
above larynx
lower respiratory system
below larynx
conducting portion
from nasal cavity to terminal bronchioles
respiratory portion
respiratory bronchioles and alveoli
alveoli
air filled pockets within lungs for gas exchange
pulmonary ventilation
air movement in and out of lungs
external respiration
gas exchange between blood and air at lungs' alveoli
internal respiration
gas exchange between blood and tissue cells
respiratory epithelium
for efficient gas exchange; very thin and high surface area
respiratory mucosa
epithelial layer that lines conducting portion of respiratory system
lamina propria
underlying layer of areolar tissue that supports the respiratory epithelium; include mucous glands and smooth muscle
nasal hairs
first part of filtration system found in nasal vestibule
nasal cavity
clean and moistened by paranasal sinuses and tears that secrete mucous; has the olfactory region in the superior portion; separated by nasal septum
nasal septum
separates the nasal cavity into left and right
hard palate
forms floor of nasal cavity, separates nasal and oral cavities
soft palate
extends posterior to hard palate, divides superior nasopharynx from lower pharynx
nasal mucosa
functions to warm and humidify air for arrival at lower respiratory organs
pharynx
chamber shared by digestive and respiratory systems; extends from internal nares to entrances to larynx and esophagus
nasopharynx
superior portion of pharynx, contains pharyngeal tonsils and openings to left and right auditory tubes
oropharynx
middle portion of pharynx that communicates with oral cavity
laryngopharynx
inferior portion of pharynx that extends from hyoid bone to entrance of larynx and esophagus
thyroid cartilage
Adam's apple; hyaline cartilage that forms anterior and lateral walls of larynx
cricoid cartilage
hyaline cartilage that forms posterior larynx
epiglottis
elastic cartilage that prevents entrance of bolus into respiratory tract
vestibular ligaments
lie within vestibular folds to protect vocal folds
phonation
sound production at the larynx
articulation
modification of sound by other structures
trachea
aka windpipe that extends from the cricoid cartilage into mediastinum; surrounded by cartilaginous disks
extrapulmonary bronchi
branches outside the lungs
intrapulmonary bronchi
branches within the lungs
carina
where the trachea bifrucates and split into primary bronchi
primary bronchus
one that goes into each lung branching off from trachea at the carina
hilum
where pulmonary nerves, blood vessels, and lymphatics enter a groove into an organ, anchored by connective tissue
root of lung
complex of connective tissue, nerves, and vessels in hilum
base of lungs
inferior portion of each lungs rest on superior of diaphragm
secondary bronchus
aka lobar bronchii; branch that comes off the primary bronchus
bronchitis
inflammation of bronchial walls causing constriction and breathing difficulty
bronchiole
has no cartilage and is dominated by smooth muscle
bronchiodialation
dilation of bronchial airways by sympathetic autonomic nervous system activation, reduces resistance
bronchiolconstriction
constricts bronchioles by histamine release
asthma
excessive stimulation and bronchioconstriction that restricts airflow
pulmonary surfactant
oily secretion of phospholipids and proteins that decreases alveolar surface tension allowing the lungs to expand
respiratory distress
difficult respiration due to alveolar collapse when pneumocytes do not produce enough surfactant
pneumonia
inflammation of lobules causing fluid to leak into alveoli compromising the function of the respiratory membrane
high altitude pulmonary edema
results from a high blood pressure in the lungs causing smooth muscle to constrict causing leakage in the lungs; tolerability and symptoms varies from person to person due to their fitness, acclimation, and genetics
pleural fluid
lubricates space between parietal and visceral pleura surrounding lungs
atmospheric pressure
weight of air that drives oxygen into lungs
respiratory cycle
cyclical changes in interapleural pressure operate the respiratory pump
tidal volume
amount of air moved in and out of lungs in a single respiratory cycle
pnemothorax
injury to chest wall that allows air into pleural cavity
alelectasis
aka collapsed lung; result of pnemothorax
quiet breathing
eupena, involves active inhalation and passive exhalation
deep breathing
use of diaphragm
shallow breathing
use of rib cage
elastic rebound
occurs when inhalation muscles relax allowing muscles and lungs to recoil returning body to original position
hyperpnea
aka forced breathing that involves active inhalation and exhalation; maximum levels occur in exhaustion
respiratory minute volume
amount of air moved per minute to measure pulmonary ventilation
alveolar ventilation
amount of air reaching alveoli each minute; calculated as [(tidal volume) - (anatomic dead space)] times (respiratory rate)
anatomic dead space
volume of air remaining in conducting passages that does not reach alveoli
sudden infant death syndrome
SIDS, may result from connection problems between pacemaker complex and respiratory center
cranial nerve IX
glossopharyngeal nerve that is stimulated by changes in blood pH or the pressure of oxygen
cranial nerve X
vagus nerve from aortic bodies stimulated by blood pH or pressure of oxygen
hypercapnia
increase in arterial carbon dioxide pressure that stimulates breathing
hypoventilation
abnormally low respiration rate
hyperventilation
excessive breathing that causes low pressures of carbon dioxide which stimulates chemoreceptors to decrease respiratory rate
barocepter reflexes
affected by blood pressure; when it falls, respiration increases
Herring-Breor reflexes
involved in forced breathing to prevent over-expansion of lungs
protective reflexes
triggered by receptors in respiratory tract to cough, sneeze and laryngeal spasm when exposed to chemical irritants and mechanical stimuli
apnea
suspended respiration followed by explosive exhalation to clear airways by sneezing or coughing
laryngeal spasm
temporary closure of airways to prevent foreign particles and substances from entering
emphysema
breakdown of alveolar walls, affects individuals over age 50, dependent on exposure to respiratory irritants such as cigarette smoke
nervous system
includes all neural tissues in the body, including brain, spinal cord
neurons
cells that send and receive signals as the functional unit; perform all communication, information processing and control functions of the nervous system
neuroglia
aka glial cells; cells that support and protect neurons
central nervous system
brain and spinal cord enclosed in bony coverings
peripheral nervous system
includes nerves and ganglia
nerve
bundle of axons in connective tissue for the PNS; examples include spinal and cranial nerves
ganglion
swelling masses of cell bodies in a nerve surrounded by neuroglia; for the PNS
cranial nerves
connect to brain
spinal nerves
exiting spinal cord
afferent division
sensory; carries sensory information from PNS sensory to CNS
visceral motor division
has effectors of cardiac, smooth muscle and glands
receptors
detect changes or responds to stimuli
effector
responds to efferent signals, organs that carry out responses
somatic nervous system
controls skeletal muscle contractions
autonomic nervous system
controls subconscious actions of smooth and cardiac muscles and gradular secretions
sympathetic division
has a stimulating effect
parasympathetic division
has a relaxing effect
sensory neuron
afferent neuron; detects changes in body and external environment; information transmitted into brain or spinal cord
interneuron
association neurons that integrate information in-between sensory and motor pathways; found in brain, spinal cord, and autonomic ganglia; involved in higher function of memory, planning, and learning
motor neuron
efferent neuron; sends signals out to muscles and gland cells
excitability
aka irritability; ability to change and respond to changes in body and stimuli
conductivity
produce travelling electrical signals
secretition
release of chemical neurotransmitters when stimulated by an electrical signal
soma
cell body of neuron that has a single central nucleus with large nucleolus
dendrite
receive signals and branch off the cell body
neurofilaments
act as microfilaments
neurotubules
replacement of microtubules
neurofibrils
bundles of neurofilmanets that provide support for dendrites and axon
Nissel bodies
dense areas of RER and ribosomes that make neural tissue appear gray
dendrititic spine
fine processes on a dendrite that receive information from other neurons; 80-90% of neuron surface area
nerve fiber
propagates signal to target cell
axon hillock
where the cell body meets the axon and attaches to initial segment
axoplasm
cytoplasm of axon that contains neurotubules, neurofibrils, enzymes, and organelles
axolemma
specialized cell membrane that covers axoplasm
multipolar neuron
most common in CNS, includes all skeletal muscle motor neurons; many dendrites to one axon
bipolar neuron
one way directional flow that has one dendrite to one axon; found in olfactory, retina, ear and other special sensory organs
unipolar neuron
found in sensory neuron of PNS; sensory from skin and organs to spinal cord
anaxonic neuron
more rare; many dendrites to no axons; help in visual processes and found in brain and senses organs
fast anterograde axonal transport
moves in either direction up to 400 mm/day for organelles, enzymes, vesicles, and small molecules
fast retrograde
moves recycled materials and pathogens
slow axonal transport
aka plasmic flow; moves cytoskeletal and new axoplasmic materials at 10 mm/day during repair and regeneration in damaged axons
neuroglia
half the volume of the nervous system that preserves physical and biochemical structure of neural tissue and are essential to survival and function of neurons
ependymal cells
cells with highly branched processes; contact neuroglia directly; form epithelium called ependyma; line central canal and ventricles of the brain to secrete CSF, circulate and monitor CSF, and contains some stem cells for repair
cerebral spinal fluid
provides nutrients to brain, provides cushion
astrocytes
large cell bodies with many processes that maintain conditions of central nervous system with cerebral spinal fluid, conversion of glucose to lactate, development of new nerves, and brain blood barrier
oligodendrocytes
smaller cell bodies that wrap around axons to form myelin sheaths
microglia
smallest neuroglia that come from monocytes and are found in areas of infection, trauma, or stroke
Schwann cells
myelinate fibers of PNS
satellite cells
cells found in neuroglia, but function is unknown
myelin
insulating layer around a nerve fiber; composed of 20% protein and 80% lipids; white matter
nodes of ranvier
gaps between myelin segments
initial segment
area between first Schwann cell
trigger zone
area between initial segment and axon hillock where signal begins
slow signals
provide information to stomached and dilate pupil
fast signals
supply skeletal muscles and transport sensory signals for vision and balance
presynaptic neuron
first neuron that releases neurotransmitters to stimulate the second neuron
postsynaptic neuron
second neuron that receives neurotransmitters to start action potential and responds
synaptic cleft
gap between presynaptic membrane and post synaptic membrane
synaptic knob
expanded area of axon of presynaptic neuron that releases neurotransmitters
synaptic vesicles
storage area in neurons for neurotransmitters
neurotransmitters
chemical messengers that are released at the presynaptic membrane to affect receptors at the post synaptic membrane; broken down by enzymes and reassembled at synaptic knob
electrical synapse
direct physical contact between cells locked by gap junctions; allow ions to pass between cells and are found in brain, eye, and ciliary ganglia
chemical synapse
signal transmitted across a gap by chemical neurotransmitters; found in most synapses between neurons; cells are not in direct contract
neuromuscular junction
synapse between neuron and muscle
neuroglandular junction
synapse between neuron and gland
connexons
gap junctions that interlock electrical synapses
excitatory neurotransmitter
causes depolarization of post synaptic membranes and promotes action potentials
inhibitory neurotransmitter
cause hyperpolarization of post synaptic membranes; suppresses action potentials
cholinergic synapse
any synapse that releases acetylcholine
acetylcholine
a neurotransmitter that usually promotes action potentials; inhib8its at neuromuscular junctions
axodendritic synapse
axon connects to dendrite
axosomatic synapse
axon connects directly to soma
axoaxonic synapse
axon connects to another axon
neuromodulator
other chemicals released by synaptic knob that are long term, have multiple steps, may act with or without a neurotransmitter
norepinephrine
released by adrenergic synapses as a an excitatory and depolarizing effect; widely distributed in brain and portions of autonomic nerve system
dopamine
CNS neurotransmitter that may be excitatory or inhibitory; involved in Parkinson's disease or cocaine use
serotonin
CNS neurotransmitter that affects attention and emotional states
Gama aminobutyric acid
inhibitory effect, function is not well known
monoamines
synthesized by replacing amino acids with another functional group, includes catecholamine and indolamines
catecholamines
epi, NE, and dopamine
indolamines
serotonin and histamine
neuropeptides
chains of 2-40 amino acids that are stored in secretory granules called dense core vesicles; act at lower concentrations and have longer lasting effects; some released from non-neural tissue and may function as hormones
neural pool
interneurons that share specific body function
discharge zone
single cell can produce firing
facilitated zone
single cell can only make it easier for a post synaptic cell to fire
diverging circuit
one input, lots of outputs; found in stretch reflex
converging circuit
input from many fibers to one neuron
reverberating circuits
neurons stimulate each other in linear sequence but one cell restimulates the first cell to start the process over
parallel after discharge circuit
higher order pathway that has input neurons that undergo several pathways and continues stimulation after initial input firing has ceased
engram
aka memory trace; physical basis of memory as a synaptic pathway
immediate memory
ability to hold something in thoughts for a few seconds; used in reading, sense of present; uses reverberating circuits
short term memory
lasts from a few seconds to a few hours; uses reverberating circuits; facilitation makes memory retention easier
tetanic stimulation
rapid repetitive signals that cause calcium to build up increasing likelihood of firing neuron; used as part of facilitation
post-tetanic potentiation
jogging memory; calcium levels in synaptic knob remain elevated; little stimulation required for memory recovery
declarative long term memory
retention of facts as text
procedural long term memory
retention of motor skills
long term memory
physical remodeling of synapses with new branches of axons or dendrites; molecular changes for the long term such as more neurotransmitter receptors, more proteins, nitric oxide, and more neurotransmitters
Alzheimer's disease
memory loss for recent events, moody and combative, loss of ability to walk, talk, or eat; diagnosis confirmed at autopsy by atrophy of gyri in cerebral cortex, presence of neurofibrillary tangles and senile plaques; also degeneration of cholinergic neurons, deficiency of ACh and nerve growth factor
Parkinson's disease
chronic and progressive degenerative disease of brain that impairs motor control, speech, and other functions; degeneration of dopamine releasing neurons; involuntary muscle contractions like pill rolling motion, facial rigidity, slurred speech, illegible handwriting, and slow gait; treated by dopamine precursors, MAO inhibitor to slow neural degeneration, or surgical techniques, usually drugs and physical therapy
rabies
retrograde flow from the bite of an animal that moves into peripheral tissues; from there, virus enters synaptic knobs and peripheral axons, then moves to CNS and is then fatal
primary tumor
75% of tumors; originate in CNS; in adults results from division of abnormal neuroglia; children receive tumors from division of stem cells until age 4
secondary tumor
tumor that originates from metastasis of cancer cells that originate elsewhere
tumor
abnormal growth of tissue with various symptoms depending on location; treated with radiation, surgery, or a combination of the two
medullary cone
aka conus medullaris; tapered end tip of spinal cord
cauda equina
from L2 to S5 nerve; roots resemble horse's tail
enlargement
amounts of gray matter in segments involved with sensory and motor nerves of limbs
cervical enlargement
nerves of shoulder and upper limbs
lumbar enlargement
nerves of pelvis and lower limbs
denticulate ligaments
stabilize spinal cord from side to side; extend from pia mater to dura mater
ventral root
contains axons of motor neurons
dorsal root
contains axons of sensory neurons
dorsal root ganglia
contains cell bodies of sensory neurons
spinal nerves
where dorsal and ventral roots join
mixed nerve
a nerve that carries both afferent and efferent fibers
spinal meninges
specialized protective membranes that isolate spinal cord from surroundings
meningitis
viral or bacterial infections of meninges causing inflammation; creates symptoms of neck problems, fatigue, and high fever
dura mater
tough collagenous membrane surround by epidural space, filled with fat and blood vessels
arachnoid mater
layer of simple squamous epithelium lining dura mater and loose mesh of fibers filled with cerebral spinal fluid
pia mater
delicate membrane adherent to spinal cord; filium terminale and denticulate ligaments anchor the spinal cord
spina bifida
failure of vertebral arch to close covering spinal cord; folic acid consumption for mother decreases risk; congenital defect in 1 baby out of 1000
gray matter
neuron cell bodies with little myelin; area of integration and command initiation; organized into nuclei
white matter
myelinated axons that carry information from place to place; organized into columns
white columns
aka funiculi; bundles of myelinated axons that carry signals up and down to and from brainstem
tracts
aka fasciculi; fibers with similar origin, destination, and function; found in the CNS; bundles of axons
nuclei
functional groups of gray matter as a collection of cell bodies in the CNS, specifically deep in the brain
poliomyelitis
caused by polio virus spread by fecally contaminated water; weakness progresses to paralysis and respiratory arrest; destruction of motor neurons and skeletal muscle atrophy
amylotrophic lateral sclerosis
aka Lou Gehrig's disease; sclerosis of spinal cord due to astrocyte failure to reabsorb glutamate neurotransmitters; leads to paralysis and muscle atrophy; not infectious
epineurium
outer layer that covers nerves; dense network of collagen fibers
perineurium
middle layer that surrounds fascicle; divides nerves into fascicles; blood vessels penetrate only to perineurium
endoneurium
inner layer that separates individual nerve fibers surrounds individual axons
dorsal ramus
contains somatic and visceral motor fibers, innervates the back
ventral ramus
larger branch, innervates ventrolateral structures and limbs
interoceptors
sense internal environment
exteroceptors
sense external environment
proprioreceptors
senses body position in space, found in joints, used to detect movement
dermatome
bilateral region of skin monitored by specific pair of spinal nerves
peripheral neuropathy
regional loss of sensory or motor function causing pain and numbness in hands and feet; caused by trauma, compression, infections, metabolic problems, and exposure to toxins; treated with medication and symptoms improves over time
shingles
skin eruptions along path of nerve caused by varicella-zoster virus that remains for life in dorsal root ganglia; occurs after age 50 if immune system is compromised; no special treatment
nerves plexus
complex interwoven network of nerve fibers formed from blended fibers of ventral rami of adjacent spinal nerves; controls skeletal muscles of neck and limbs
cervical plexus
includes ventral rami of spinal nerves C1-C5; innervates neck, thoracic cavity, and diaphragmatic muscles
brachial plexus
includes ventral rami of spinal nerves C5-T1; innervates pectoral girdles and upper limbs
lumbar plexus
includes ventral rami of spinal nerves T12-L4
sacral plexus
includes ventral rami of spinal nerves L4-S5
sciatica
disturbance of sciatic nerve causing shooting pains down leg
innate reflexes
basic neural reflexes, formed before birth
acquired reflexes
rapid automatic reflexes, learned motor patterns
somatic reflexes
involuntary control of nervous system such as superficial reflexes of skin, mucous membranes, and stretch or deep tendon reflexes
visceral reflexes
autonomic reflexes that control systems other than muscular system
monosynaptic reflex
sensory neuron synapses directly onto motor neuron
polysynaptic reflex
at least interneuron between sensory and motor neuron
spinal reflex
reflex occurs in spinal cord
cranial reflex
reflex occurs in brain
muscle spindles
bundles of small specialized interfusal muscle fibers innervated by sensory and motor neurons surrounded by extrafusal muscle fibers that maintain tone and contract muscles
postural reflexes
stretch reflex that maintains normal upright posture where a stretched muscle responds by contracting automatically maintaining balance
tendon reflex
prevents skeletal muscles from developing too much tension and breaking tendons
withdrawal reflex
move body part away from pain or pressure stimulus; strength and extent of response dependent on intensity and location of stimulus
flexor reflex
polysynaptic reflex arc; neural circuitry in spinal cord controls sequence and duration of muscle contractions
ipsilateral reflex arc
stretch, tendon, and withdrawal reflex occurs on the same side of body as stimulus
contralateral reflex arc
reflex arc where response occurs on the opposite side of the stimulus
Babinski reflex
stroking the soles of the foot; normal for infants, may indicate CNS damage in adults
spinal cord trauma
occurs in traffic accidents, leads to paralysis, poses risk of respiratory failure, spinal shock, post-traumatic infarction
neurological assessment
evaluates mental status, cranial nerve function, sensory function, reflex function, autonomic status, and cerebral vasculature by looking at special senses, general senses, motor function, deep tendon reflexes, and level of consciousness
cerebellum
muscle coordination; coordinates somatic motor process; contains 50% of the neurons; connected to brainstem by peduncles; work at evaluating sensory input, timekeeping, pitch and planning tasks
cerebrum
conscious thought processes; intellectual functions; memory storage and processing; 83% of brain volume; composed of four lobes
diencephalon
composed of the thalamus and hypothalamus
thalamus
relay and process centers for sensory information from cerebellum to motor cortex; emotion and memory function
hypothalamus
centers controlling emotions, autonomic functions and hormone production, such as autonomic NS, thermoregulation, food and water intake, sleep and circadian rhythms, and memory
mesencephalon
processing of visual and auditory data, generate somatic motor reflexes, maintains consciousness
pons
relays sensory information to cerebellum and thalamus, subconscious motor centers like posture, sleeping, hearing, balance, taste, ye movements, facial expression, facial sensation, respiration, swallowing, and bladder control; bulge in brainstem
medulla oblongata
relays sensory information to thalamus and brain stem, autonomic centers for visceral functions such as cardiac centers, vasomotor centers, respiratory centers, and reflex centers
rostral
towards the forehead
caudal
towards the spinal cord
gyri
folds and protrusions of the brain
sulci
grooves of the brain
cortex
surface layer of gray matter of the brain
epidural hemorrhage
blood forced between dura mater and cranium
subdural hemorrhage
more common to occur; blood forced between dura and arachnoid mater; gradual, variable, hard to diagnose
choroid plexus
produces cerebral spinal fluid
blood brain barrier
isolates CNS from general circulation by using tight junctions; prevents diffusion of materials between endothelial cells; allows only small lipid soluble materials like oxygen, carbon dioxide, nicotine and anesthetics through
blood-CSF barrier
prevents free access of substances to CNS; found at the choroid plexus using tight junctions
superior peduncle
output to midbrain, thalamus, and cortex
middle peduncle
input from cerebral cortex and inner ear
inferior peduncle
spinocerebellar tracts for proprioception
tegmentum
connects to cerebellum and helps control fine movements through red nucleus
substantia nigra
sends inhibitory signals to basal ganglia and thalamus
central gray matter
responsible for pain awareness
superior colliculus
tracks moving objects, blinking, pupillary and head turning reflexes
inferior colliculus
reflex of turning head to sounds
reticular formation
clusters of gray matter scattered throughout pons, midbrain, and medulla; regulate balance and posture, as well as cardiac and vasomotor centers; regulate sleep and conscious attention
frontal lobe
responsible for voluntary motor functions, planning, mood, smell, and social judgment
parietal lobe
receives and integrates sensory information, such as touch, pressure, and pain
occipital lobe
visual center of brain
temporal lobe
areas for hearing, smelling, learning, memory, and emotional behavior
projection tract
from brain to spinal cord, forms internal capsule
commissural tract
cross to opposite hemisphere e.g. corpus callosum and anterior and posterior commisures
association tracts
connects lobes and gyri within a hemisphere
stellate cells
cells with dendrites that project in all directions
pyramidal cells
axons pass out of these areas
basal nuclei
masses of gray matter deep to cortex; includes caudate nucleus, putamen, and globus pallidus
limbic system
includes amygdala, hippocampus, and cingualte gyrus
electroencephalogram
records voltage changes from postsynaptic potentials in cerebral cortex
alpha wave
occurs when awake or resting with eyes closed
beta wave
eyes open, performing mental tasks, intense concentration
theta wave
sleep or emotional stress; found in children and frustrated adults
delta wave
deep sleep wave
sleep paralysis
inhibition of muscular activity
REM sleep
rapid eye movement under eyelids; vital signs increase; EEG resembles awake person; dreams and penile erection occur
agnosia
results from lesion to temporal lobe; causes inability to recognize objects
prosopagnosia
inability to recognize faces
anterograde amnesia
no new memories form, usually an issue with the hippocampus
retrograde amnesia
can't remember old memories
hippocampus
organizes sensory and cognitive information into a new memory
amygdala
emotional memory
prefrontal cortex
controls expression of emotion
homunculus
map of the brain that shows receptors dedicated to specific parts of the body
Wernicke area
permits recognition of spoken and written language, creates plans of speech
Broca area
generates motor signals for larynx, tongue, cheeks, and lips; transmits to primary motor cortex for action
cerebral lateralization
separation of hemispheres to favor particular skills
aphasia
language deficit from lesions in same hemisphere as Wernike or Brocca area
nonfluent aphasia
lesion to Brocca area resulting in slow speech, difficulty in choosing words
fluent aphasia
lesion to Wernike area resulting in normal and excessive speech, but it makes little sense
anomic aphasis
speech and understanding are normal, but text and pictures make no sense
left hemisphere
categorical hemisphere that is specialized for language, sequential and analytical reasoning
right hemisphere
representational hemisphere for perceiving information more hollistically, perception of spatial relationship, patterns, comparison of special sense, imagination, and insight, music and artistic skills
olfactory nerve
1 responsible for sense of smell
optic nerve
2 provides vision and damage causes blindness in visual field
oculomotor nerve
3 responsible for eye movement, opening of eyelid, constriction of pupil and focusing; damage causes drooping eyelid, dilated pupils, double vision, difficulty in focusing, and inability to move eyes in certain directions
trochlear nerve
4 eye movement of the superior oblique muscle; damage causes double vision and inability to rotate eye inferiorly
trigeminal nerve
5 sensory to face, such as touch, pain, and temperature, and muscles of mastication; damage produces loss of sensation and impaired chewing
abducens nerve
6 produces eye movement via lateral rectus muscle; damage results in inability to rotate eye laterally
facial nerve
7 motor - facial expressions, salivary glands, tears, nasal and palatine glands; sensory - taste on anterior 2/3 of tongue; damage produces sagging facial muscles and disturbed sense of taste (no sweet and salty)
vestibulocochlear nerve
8 provides hearing and sense of balance; damage produces deafness, dizziness, nausea, and loss of balance
glossopharyneal nerve
9 responsible for swallowing, salivation, gagging, control of blood pressure, and respiration; also sense 1/3 of tongue; damage results in loss of bitter and sour taste and impaired swallowing
vagus nerve
10 travels from cranium to many viscera such as lungs, heart, liver, stomach, spleen, kidney, and intestines; responsible for swallowing, speech, and regulation of viscera; damage causes hoarseness or loss of voice, impaired swallowing and can be fatal if both nerves are cut
accessory nerve
11 swallowing, head, neck, and shoulder movement; damage causes impaired head, neck, shoulder movement; head turns toward injured side
hypoglossal nerve
12 tongue movements for speech, food manipulation and swallowing; if both are damaged - can't protrude tongue
trigeminal neuraglia
aka tic doulereux; recurring episodes of intense stabbing pain in trigeminal area such as the mouth or nose; pain triggered by touch, drinking, or washing face; treatment may require cutting nerve
bell's palsy
disorder of facial nerve causes paralysis of facial muscles on one side; may appear abruptly with full recovery within 3-5 weeks
preganglionic fibers
in brain and spinal cord, axons of preganglionic neurons, leave CNS and synapse on ganglionic neurons of the ANS visceral motor neurons
autonomic ganglia
ganglionic neurons innervate visceral effectors such as smooth muscle, cardiac muscle, glands, and adipose tissue
post ganglionic fibers
axons of ganglionic neurons in the ANS's visceral motor system, leave collateral ganglia, extend through abdominopelvic cavity
enteric nervous system
third division of ANS, extensive network in digestive tract walls, complex visceral reflexes
collateral ganglia
anterior to vertebral bodies, contain ganglionic neurons that innervate tissues in abdominopelvic cavity
splanchnic nerve
formed by preganglioninc fibers that innervate collateral ganglia in the dorsal wall of abdominal cavity, originate as paired ganglia
celiac ganglion
pair of interconnected masses of gray matter that may form single mass or many interwoven masses that innervate stomach, liver, gallbladder, pancreas, and spleen
suprarenal medullae
very short axons that release neurotransmitters into bloodstream, function as hormones to affect target cells throughout body
ganglionic neurons
release neurotransmitters at specific target organs
telodendria
sympathetic varicosities that resemble strings of pearl that have neurotransmitter vesicles for the sympathetic system
alpha 1
alpha receptor that releases intracellular calcium ions from reserves in endoplasmic reticulum, has an excitatory effect on target cell
alpha 2
lowers cAMP levels in cytoplasm, inhibitory effect on cell, helps coordinate sympathetic and parasympathetic activities
beta receptors
affect membranes in many organs, triggers metabolic changes in target cell, stimulation increase intracellular cAMP levels
beta 1
increases metabolic activity
beta 2
triggers relaxation of smooth muscles along respiratory tract
beta 3
leads to lipolysis
lipolysis
break down triglycerides in adipocytes
cholinergic sympathetic terminals
innervate sweat glands of skin and blood vessels of skeletal muscles and brain; stimulate sweat gland secretion and dilate blood vessels
nitroxidergic synapses
release nitric oxide as neurotransmitter; neurons innervate smooth muscle in walls of blood vessels in skeletal muscle and the brain; produce vasodilatation and increased blood flow
autonomic nuclei
contained in mesencephalon, pons, and medulla oblongata
terminal ganglion
of the parasympathetic system; near target organ, usually paired
intramural ganglion
of the parasympathetic system; embedded in tissues of target organs as clusters of ganglion cells
anabolic system
stimulation increases nutrient content of food and allows cells to absorb more nutrients
muscarinic receptors
at cholinergic neuromuscular or neuroglandular junctions for the parasympathetic and a few cholinergic junctions of the sympathetic system, contain G proteins, have a longer lasting effect than nicotine receptors, can be excitable or inhibited
nicotinic receptors
on surfaces of ganglion cell and exposure to Ach causes excitation of ganglionic nerve or muscle fiber
nicotine
binds to nicotinic receptors and target autonomic ganglia and skeletal neuromuscular junctions; can cause vomiting, diarrhea, high blood pressure, rapid heart rate, sweating, profuse salivation, convulsions, and may result in coma or death
muscarine
binds to muscarinc receptors; targets parasympathetic neuromuscular or neuroglandular junctions; can cause salivation, nausea, vomiting, diarrhea, constriction of respiratory passages, low blood pressure, and slow heart rate
dual innervation
when the parasympathetic and sympathetic systems compete for control over a common visceral organ
autonomic plexus
nerve networks in the thoracic and abdominopelvic cavities that are formed by sympathetic postganglionic fibers and parasympathetic preganglionic fibers
cardiac and pulmonary plexuses
autonomic fibers entering thoracic cavity intersect for control of heart and lungs
esophageal plexus
descending branch of vagus nerve meet the splanchnic nerves
celiac plexus
innervates viscera within abdominal cavity
hypogastric plexus
innervates digestive, urinary, and reproductive organs of pelvic cavity
autonomic tone
background level of activity that can be affected by dual innervation
long reflexes
autonomic equivalents of polysynaptic reflexes; visceral sensory neurons deliver information to CNS along dorsal root of spinal nerves and ANS carries motor commands to visceral effectors; found in the majority of organs
short reflexes
bypass CNS by using sensory neurons and interneurons located within autonomic ganglia; controls simple motor response with localized effects; found in the digestive system
sympathomimetrics
enhance activity of sympathetic system, stimulates receptors or increase NE release
sympatholytics
suppress sympathetic activity by blocking receptors or inhibit NE release
parasympathomimetrics
enhance parasympathetic activity
parsympatholytics
suppress parasympathetic activity
Prozac
blocks reuptake of serotonin to prolong its mood elevating effect
MAO inhibitors
interferes with breakdown of monoamine neurotransmitters
caffeine
competitively competes with adenosine at the receptor site to prevent sleepiness
sensory transduction
convert stimulus energy into nerve energy
receptor potential
local electrical change in receptor cell
adaptation
conscious sensation declines with continued stimulation
intensity
frequency, based on the number of fibers and which fibers
duration
change in firing frequency over time
phasic receptor
burst of activity and quickly adapt, such as the smell and hair receptors
tonic receptor
adapt slowly, generate impulses continually, such as proprioceptors
general senses
widely distributed throughout the body
special senses
senses limited to the head
unencapsulated nerve endings
dendrites are not wrapped in connective tissue
hair receptors
monitor movements of hair
encapsulated nerve endings
dendrites wrapped by glial cells or connective tissue
tactile corpuscles
phasic receptors for light touch and texture
krause end bulb
phasic receptor for touch in mucous membranes
lamellated corpuscles
phasic receptors that respond to deep pressure, stretch, tickle, and vibrations
ruffini corpuscles
tonic receptors that respond to heavy touch, pressure, joint movements, and skin stretching
1st order neuron
afferent neuron that detects touch, pressure, and proprioception on large, flat, myelinated axon and heat and cold on small unmyelinated slow fibers
2nd order neuron
decussation to opposite side in spinal cord or medulla/pons end in thalamus, except for proprioception (cerebellum)
3rd order neuron
thalamus to primary somesthetic cortex of cerebrum
nocioreceptors
allow awareness of tissue injuries, found in all tissues except the brain
somatic pain
comes from skin, muscles, and joints
visceral pain
pain that comes from stretch, chemical irritants, or ischemia of viscera
spinoreticular tract
pain signals reach reticular formation, hypothalamus, and limbic system triggering visceral, emotional, and behavioral reactions
referred pain
misinterpreted pain that is assume from the brain, usually a slow and deep pressure
endogenous opiods
include painkillers, analgesics, enkephalins, endorphins, and dynorphins produced by CNS under stress to act as neuromodulators to block transmission of pain
spinal gating
stopping pain signals from the dorsal horn
gustation
sensation of taste resulting from action of chemicals on taste buds
filiform
type of lingual papillae that senses texture
fungiform
papillae found at the tips and sides of tongue
foliate
papillae without any taste sensation
vallate
aka circumvallate; conbtains 1/2 of taste buds, found at rear of tongue
umami
taste of amino acids (MSG)
mouth feel
detected by lingual nerves in papilla that senses for texture, aroma, temperature, and appearance
sound
audible vibrations of molecules
pinna
fleshy auricle directs air vibration down external auditory meatus
cerumen
earwax formed from glandular secretitions and dead cells
auditory tube
aka eustachian tube connects to nasopharynx and helps with equalizing air pressure on tympanic membrane
bony labyrinth
passageways in temporal bone that make up the inner ear
inner hair cell
stereocilia in the organ corti that assist in hearing
outer hair cell
adjust cochlear responses to different frequencies and increases auditory precision
tympanic membrane
has 18x the area of the oval window; used to transfer sound to the ossicles to the endolymph
tensor tympani
muscle that tenses tympanic membrane to prevent hearing loss during loud sounds
stapedius muscle
reduces mobility of stapes in response to slowly building sounds
equilibrium
control of coordination and balance
static equilibrium
perceived by macula in response to head orientation
dynamic equilibrium
perception of motion or acceleration using macula or cristae
macula
hair cells with stereocilia and kinocilium buried in otolith membrane
otoliths
add to the density and inertia to enhance the sense of gravity and motion
cristae ampullaris
hair cells buried In a mound of gelatinous membrane; orientation causes ducts to be stimulated by rotation in different planes
vestibular cortex
awareness of spatial orientation and movement
vision
perception of light emitted or reflected from objects in the environment
eyebrows
provide facial expression
eyelids
aka palpebra, block foreign objects, help with sleep, moisten eyes; consist of orbicularis oculi muscle and tarsal plate
tarsal glands
secrete oil to prevent tear evaporation
eyelashes
keep debris from eye
conjunctiva
transparent mucous membrane that lines eyelids and covers anterior surface of eyeball except cornea; richly innervated and vascular so heals quickly
lacrimal apparatus
provides tears to wash away foreign particles, help with diffusion of gas and contains antibacterial enzyme
fibrous layer
outer tunic layer that contains sclera and cornea
vascular layer
middle tunic that contains choroid, ciliary body, and iris
internal layer
layer that contains retina and optic nerve
cornea
transparent cover on anterior surface of eyeball
aqueous humor
serous fluid posterior to cornea, anterior to lens; produced by ciliar body and flows to posterior chamber through pupil to anterior chamber and is reabsorbed by the canal of Schelmm
lens
changes shape to help focus light
vitrous humor
jelly filled space between lens and retina
cataracts
clouding of the lens caused by aging, diabetes, smoking, and UV light
glaucoma
death of retinal cells due to elevated pressure within the eye, leads to obstruction of scleral venous sinuses, colored halos, and dimness of vision
retina
forms as an outgrowth of the diencephalon, attached at optic disc, pressed against rear of eyeball by vitreous
detached retina
caused by a blow to the head or lack of vitreous humor, results in blurry areas in the field of vision, disrupts blood supply and can lead to blindness
macula lutea
cells on visual axis of eye that are visual under an opthalmoscopic exam
fovea centralis
center of macula; finely detailed images due to packed receptor cells
optic disc
blind spot formed where the optic nerve exits the posterior surface of the eyeball leading to no receptor cells
pupillary constrictor
smooth muscle encircles the pupil caused by parasympathetic stimulation
pupillary dilator
spoke like myoepithelial cells dilate pupil during sympathetic stimulation
photopupillary reflex
both pupils constrict if one eye is illuminated as a type of consensual reflex
principle of refraction
light striking the cornea is bent unless it enters at a 90 degree angle
near response
allows eyes to focus on nearby objects due to convergence of eyes and constriction of pupil
emmetropia
2 planes looking at distant objects
hyperopia
focal point forms past the fovea, farsighted, eyeball is too short; corrected with convex lenses
myopia
focal point forms too soon, nearsighted, eyeball is too long; corrected with concave lenses
rod cells
used during night vision, photoreceptor that has an outer segment with a stack of coin-like membranous discs studded with rhodopsin pigment molecules
cone cells
used for color vision, has an outer segment tapered to a point
rhodopsin
pigment in rods that have absorption peak at 500 nm, has the opsin and retinal portion; converts from cis to trans
photopsin
pigment in cones that have different amino acids that determine wavelength of light absorbed
duplicity theory
states that a single type of receptor is incapable of providing high sensitivity and high resolution
scotopic system
used for night vision, involves neuronal convergence for motion detection
photoptic system
used in day vision, no neuronal convergence
blue cones
have peak sensitivity at 420 nm
green cones
have peak sensitivity at 531 nm
red cones
have peak in the orange yellow range at 558 nm
color blindness
lack of a photopsin, sex linked recessive disease that causes one to be unable to distinguish red-green
depth perception
ability to judge distance to objects by using two images