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32 Cards in this Set

  • Front
  • Back
Tests with the lowest likelihood of affecting diagnosis or management of syncope (4)
CT head, doppler US, EEG, cardiac enzyme
highest contraceptive efficacy (typical failure rate <1%) with the lowest cost
IUD
NOTE: Initiate treatment for dysmenorrhea without further evaluation,
unless pelvic pathology is suspected.
Treatment of allergic conjunctivitis
ral antihistamines, topical antihistamines, and artificial tears; antibiotic treatment is not indicated.
when should imaging be considered in the diagnosis of sinusitis
immunocompromised patients at risk for unusual organisms, such as fungal or pseudomonal sinusitis
NOTE: In patients with dental infections without cellulitis or systemic symptoms, antibiotic therapy is
not necessary if dental intervention can be performed within several days.
when is blood transfusion indicated
symptomatic anemia, preop Hb <6, postop Hb <7; significant cardiovascular disease and Hb bet 6-10
refers to the degree to which the investigators' conclusions (usually implying cause and effect) are supported by the study
Internal validity
refers to the generalizability of the study
External validity
the probability of detecting a difference between two groups when a true difference exists
Power
error is not random, but is applied differentially to one group
bias
bias that occurs when patients chosen for a study group have characteristics that can affect the results of the study
selection bias
a third factor that influences both exposure (treatment) and outcome
confounder
Two types of observational studies
cohort studies and case-control studies
study compares the outcomes of groups with and without exposures or treatments not initiated by the investigator
cohort study
study retrospectively compares the experience of patients who have a disease with those who do not have the disease
case-control study
patients with disease may be more likely to remember previous exposures
recall bias
study assesses for both exposure and disease at the same time point (rather than prospectively or retrospectively)
cross-sectional study
a report of clinical outcomes in a group of patients; the absence of a control group prevents any conclusions about the effectiveness of the treatment
case series
studies compare outcomes, in aggregate, of two different populations
Epidemiologic studies
erroneously assuming that population-level associations imply individual-level associations.
ecologic fallacy
quality sources of evidence (highest to lowest) (5)
meta-analysis, qualitative systematic reviews, RCTs, cohort studies, case-control studies
summarize existing experimental or observational studies in a rigorous way
systematic reviews
Systematic reviews that quantitatively combine data
meta-analyses
research intended to produce evidence that can help patients, physicians, and policy makers better understand the effectiveness, benefits, and harms of treatments or procedures.
Comparative effectiveness research (CER)
NOTE: PPV increases with increasing prevalence of disease;
NPV increases with decreasing prevalence of disease.
relative comparisons in statistics
relative risk, odds ratio, and hazard ratio
reciprocal of the ARR
NNT
reciprocal of the absolute risk increase
number needed to harm (NNH)
an indicator of the ability of a test to detect a disease if it is present
sensitivity
reflects how effectively a test can exclude illness in a patient without the disease
specificity
ratio of the probability of a particular test result (positive or negative) among patients with a disease to the probability of that same result among patients without the disease
likelihood ratio