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25 Cards in this Set

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MC soft tissue tumor
lipoma
lipoma:
-site?
subcutis of trunk+proximal extremities

(makes sense: you get fat in your trunk [stomach, boobs] + prox ext [thighs])
resembles mature fat?
lipoma (vs liposarcoma)
resembles fetal fat?
liposarcoma (vs lipoma)

hallmark of liposaracoma=
lipoblast (mimics fetal fat cell)
reactive pseudo-sarcomatous proliferation
nodular fasciiitis
clinnically alarming b/c rapid growth
nodular fasciitis (benign0
nodular fasciitis:
sote?
subcutaneous or intramuscular nodule
-in forearm, chest, back
myositis ossificans:
-def?
-site?
ossifying benign fibrous lesion

site=prox ext: intramuscular=pretty unique (muscle="myo"sitis)

(or subcutaneous)
superficial fibromatoses
1.palmar: Dupuytren's contracture
2.plantar
3.penile: Peyronie's Dz
deep seated fibromatosis
AKA desmoid

extraabdominal: trunk+prox ext
abdominal: ant abdom wall after pregnancy
intraabdominal: mesentary or pelvis,
assoc w/Gardner's syndrome=
FAP+desmoid
desmoid?
=deep seated fibromatosis
(extraabdominal, abdominal, intra-ab)
"herringbone pattern"
fibrosarcoma
Malignant Fibrous Histiocytoma
"Mother Fucking Ho"

-aggressive adult sarcoma, but deceptively circumscribed
MC soft tissue sarcoma of childhood and adolescents
rhabdomyosarcoma
tadpole cells
=rhabdomyoblast

(rhabdomyosarcoma)
"strap cells"
=rhabdomyoblast

(rhabdomyosarcoma)
rhabdomyosarcoma:
types?
=SkM

1.embryonal=MC
age: <10 y/o
site:
*(face) orbit, nasal cavity, parotid
*(groin) prostate, testicle

Type: sarcoma botryoides:
*grape
*Path: cambium layer (submucosal hypercellular zone of tumor cells)

2. alveolar
age: adolescents
site: deep muscles of extremities
grape-like appearance
sarcoma botryoides
(type of embryonal rhabdomyosarcoma)
submucosal hypercellular zone of tumor cells
=cambium layer (seen in sarcoma botryoides, which is a subtype of embryonic rhabdomyosarcoma)

EXAM: prognosis=best for embryonal (vs. alveolar)
EXAM-what has better prognosis:
embryonic rhabdomyosarcoma or alveolar?
embryonic
leiomyoma:
site?
arise from arrector pili muscle (superficial leiomyomas)
leiomyosarcoma:
site?
retroperitoneum and extremities: skin and deep soft tissues
synovial sarcoma
-near large joints, esp KNEE
-not of synovial cell origin

-cytokeratin +

types: monophasic spindle cell variant> biphasic (gland like)

genetics: t(X:18)
cytokeratin +
synovial sarcoma
t(X; 18)
synovial sarcoma