Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
what does articular cartilage contain
|
water (inc w/ OA)
collagen (type II - 90-95%; tensile strength) proteoglycans (regulate/retain water) |
|
|
how articular cartilage works
|
elastohydrodynamic lubrication (micro thin layers of synovial fuilds keep bones from touching)
|
|
|
how/why articular cartilage fails
|
- inc water content
- proteoglycans altered & shortened - collagen matrix disrupted - proteoglycans binding inc & aggrecan mol. inc in size - metalloproteinases lvl inc |
|
|
MCC cause of articular cartilage failure
|
OA
|
|
|
cure for OA?
|
nah
hardware can be placed, but it will eventually fail |
|
|
radiographic markers of OA
|
osteophytes
subchondral cysts subchondral sclerosis jt space narrowing |
|
|
how this failure is managed medically
|
med tx - PT is CI
|
|
|
how failure is managed sx'ly
|
osteomy - re-align malaligned jt
arthrodesis - fusion of affected jt; useful conditions where arthroplasty is CI (infxn; neuropathic arthropathy) 0 total jt arthroplasty - does NOT cure arthritis |
