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7 Cards in this Set
- Front
- Back
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What is the initiating event of puberty?
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Increased GnRH pulsing which stimulates LH & FSH secretion
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What is the first manifestation of gonadal axis function:
In males? In females? |
Testicular growth (onset at 11.5)
Breast budding (thelarche) |
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True or False
hCG administration in a patient who has vanishing testes syndrome WILL increase testosterone levels |
False
It will NOT, it will only increase if they have cryptorchidism |
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What is the main mechanism by which OCP's work?
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Decreasing LH & FSH
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If a male patient comes in with low levels of GnRH, FSH, LH, and sex hormones but does NOT lack any sense of smell what does he most likely have?
Is this primary or secondary hypogonadism? |
Abnormal Kisspeptin signaling (KISS1) = isolated gonadotropin deficiency
Secondary hypogonadism |
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In a patient that has complete pituitary dysfunction, what is the order in which the hormones decrease?
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1st GnRH & GH
2nd TSH 3rd ACTH |
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What are two medications known to produce androgen resistance = high testosterone, low sperm, and low LH?
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Cimetidine
Spironolactone |
